Neurology & Neurological Sciences Clinical Trials

How to Participate

Sign up here to be added to a registry for clinical trials. This survey will ask you questions about yourself and contact information that takes about 10 minutes.  

Who We Are

Learn more about our clincial trials team

 

 

Learn More

For more details on all of our clinical trials visit the SOM Clinical Trial Database or  ClinicalTrials.gov

 

 

Clinical Trials

Central Neuroscience Trials Group

Our Central Neuroscience Trials Group provides professional clinical trial staff for Investigators from both Neurology and Neurosurgery Departments, including the divisions of NeuroImmunology, Headache, Autonomic Disorders, Epilepsy, Memory disorders, and Neuroradiology. Our team supports over 100 observational and interventional, industry sponsored, and investigator-initiated projects. Our goal is to facilitate the timely, safe, and successful implementation of Neuroscience clinical research.

Neuromuscular Clinical Research Group

The Neuromuscular Research Team includes 9 Neurologists, 3 Nurse Practitioners, 3 Clinical Evaluators (Physical Therapists), a Research Administrative Associate, a Research Administrator, a Clinical Research Manager, 14 Clinical Research Coordinators, 4 Assistant Clinical Research Coordinators, a Data Analyst, a Research Scientist, a Life Science Research Professional, and a Post-Doctoral Research Fellow. Our team is involved in both adult and pediatric research. We have about 60-70 research projects at any given time including industry-sponsored clinical trials, observational studies, investigator-initiated studies, and lab-based research projects. Our goal is the translation of research findings into new and more effective clinical interventions to control or cure neuromuscular diseases.

Stroke and Neurocritical Care Clinical Research Group

The Divisions of Vascular Neurology and Neurocritical Care conduct a wide range of patient-centered research trials investigating the complex mechanisms of ischemic and hemorrhagic stroke injury, treatment, diagnosis and recovery.  The Clinical Research Team consists of a Clinical Research Manager, 9 clinical research coordinators, a regulatory coordinator, data scientist and a data analyst supporting a variety of grant funded as well as industry and donor-sponsored research.  In addition, the Divisions have a dedicated Brain Imaging Core Lab with over 17 years of experience of image processing as well as organization and storage of thousands of large imaging files.

Neuro-Oncology Clinical Research Group

The Neuro-Oncology Research Group supports 9 Investigators (4 neuro-oncologists, 3 neurosurgeons and 2 radiation therapists). It is integrated into the Stanford Cancer Center’s Clinical Trials Office and works primarily in the Cancer Center Clinics.  There are 7 research coordinators, a regulatory specialist and an operations manager that support observational, interventional, industry sponsored, and investigator-initiated projects, currently numbering 26 total. The Group’s goals are to ensure, timely, safe, and successful implementation of neuro-oncology clinical research.

Neuro-Oncology (Adult)

Newly Diagnosed Glioma

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Optune® (TTFields, 200 kHz) concomitant with Maintenance Temozolomide and Pembrolizumab Versus Optune® Concomitant with Maintenance Temozolomide and Placebo for the Treatment of Newly Diagnosed Glioblastoma (EF-41/KEYNOTE D58)
PI: Lawrence Recht, MD
Research Coordinator: Sahara Rout
Contact: ssrout@stanford.edu
ClinicalTrials.gov#: NCT06556563

Phase II Safusidenib Erbumine in Patients With Isocitrate Dehydrogenase 1 (IDH1) Mutant Glioma
Research Coordinator: Lewis Naya
Contact: lnaya@stanford.edu
ClinicalTrials.gov#: NCT05303519

 

Recurrent High Grade Glioma

Phase I Clinical Trial of Locoregionally (LR) Delivered Autologous B7-H3 Chimeric Antigen Receptor T Cells (B7-H3CART) in Adults with Recurrent Glioblastoma Multiforme (GBM)
PI: Reena Thomas, MD PhD
ClinicalTrials.gov#: NCT05474378

A Phase I Study of Multiple Doses of Neural Stem Cell-Based Oncolytic Virotherapy (NSC-CRAd-S-pk7) Administered Intracerebrally to Patients with Recurrent High Grade Gliomas
PI: Melanie Hayden Gephart, MD
ClinicalTrials.gov#: NCT05139056
 

H3K27M Mutant Glioma

Phase 1 Clinical Trial of Autologous GD2 Chimeric Antigen Receptor (CAR) T Cells (GD2CART) for Diffuse Intrinsic Pontine Gliomas (DIPG) and Spinal Diffuse Midline Glioma (DMG)
PI: Michelle Monje, MD PhD
ClinicalTrials.gov #: NCT04196413
 

Brain and Spine Metastases 

A Randomized Phase III TriaL Comparing SingLe- Versus Multi-Fraction Spine STereotActic Radiosurgery for Patients with Spinal Metastases (ALL-STAR)
PI: Erqi Pollum, MD
ClinicalTrials.gov#: NCT06173401

Pediatric Clinical Research Group

The division of child neurology maintains a broad clinical research portfolio which typically includes 15-20 active studies in pediatric epilepsy, neurogenetics, pediatric stroke, leukodystrophies, and neonatal neurology. Our research team includes a full time clinical research manager, data analyst, research administrative associate, and three full time clinical research coordinators. 

Adult Clinical Trials

For questions about clinical trials please contact our research team at neurotrials@stanford.edu.

Pediatric Clinical Trials

To find out the current status of any pediatric study please contact us at: arushi.gehani@stanford.edu

For pediatric neuro-oncology studies, please contact: Neuroonc@stanfordchildrens.org