Clinical Trials

BOOST3 – Brain Oxygen Optimization in Severe TBI Phase 3
BOOST3 is a study to learn if either of two strategies for monitoring and treating patients with traumatic brain injury (TBI) in the intensive care unit (ICU) is more likely to help them get better. More information:
Protocol ID: 49130
PI: Karen G. Hirsch, MD
Study Coordinator: Elizabeth Osborn

CERIBELL Stroke Study
The primary objective of this study is to acquire EEG data in suspected stroke patients, immediately following diagnostic brain imaging to detect potential EEG signals that differ among emergent large vessel occlusion stroke (ELVO), intracranial hemorrhage (ICH), and non-stroke patients (stroke mimics).
Protocol ID: 47822
PI: Anna Finley Caulfield, MD

ICECAP - Influence of Cooling duration on Efficacy in Cardiac Arrest Patients
The purpose of this study is to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration of induced hypothermia for neuroprotection in comatose survivors of cardiac arrest.
Protocol ID: 56493
PI: Karen Hirsch, MD

PRECICECAP - PREcision Care In Cardiac ArrEst -ICECAP
In partnership with the ICECAP trial, this project will use novel data-driven approaches to collect high resolution monitoring data from patients in the critical care unit and will use that multi-parametric data to develop newly defined patient sub-groups with differing clinical trajectories and responses to therapies.
Protocol ID: 58318
PI: Karen Hirsch, MD