Child Neuro Studies

Sunflower Syndrome - Self-Induced Photosensitive Epilepsy
PI: Fiona Baumer, MD

Epileptic encephalopathy with continuous spike-and-wave during sleep (CSWS): a review of current treatment practices
PI: Fiona Baumer, MD

Cortical Excitability, Synaptic Plasticity and Learning in Benign Epilepsy with Centrotemporal Spikes (BECTS)
PI: Fiona Baumer, MD

Consortium for Standardizing TMS (Transcranial Mangetic Stimulation) Language Mapping Protocols and Establishing Best Practice Guidelines for Using TMS in Presurgical Evaluation of Language in Children
PI: Fiona Baumer, MD

Consequences of Prolonged Febrile Seizures in Childhood
PI: William Gallentine, DO

Novel Early Imaging Markers Following Febrile Status Epilepticus
PI: William Gallentine, DO

Open-Label Safety and Efficacy Study of Cenobamate (YKP3089) in Pediatric Subjects with Partial-onset (Focal) Seizures
PI: William Gallentine, DO

Brain Connectivity Changes in Benign Epilepsy with Centrotemporal Spikes and other Pediatric Epilepsy Syndromes
PI: Fiona Baumer, MD

Diagnostic, Prognostic, and Therapeutic Applications of TMS for Epilepsy
PI: Fiona Baumer, MD

A Multi-Center Examination of Pediatric Epilepsy Surgery Evaluation in the US
PI: Ann Hyslop, MD

Investigation of Keto-Amino Acids as Novel Therapeutics for Refractory Pediatric Epilepsy
PI: Juliet Knowles, MD, PhD

A Randomized, Double-Blind, Placebo-Controlled Study To Investigate The Efficacy And Safety Of Carisbamate (YKP509) As Adjunctive Treatment For Seizures Associated With Lennox-Gastaut Syndrome In Children And Adults, With Optional Open-Label Extension (SK-LGS)
PI: Brenda Porter, MD, PhD

Children with Lennox-Gastaut Syndrome (LGS) treated with Deep Brain Stimulation (DBS)
PI: Juliet Knowles, MD, PhD

White matter structure and function in children with Lennox-Gastaut Syndrome
PI: Juliet Knowles, MD, PhD

A Multimodal Biomarker-based Predictive Model for Infantile Spasms
PI: Ann Hyslop, MD

PERF Genetic Epilepsy Registry
PI: Juliet Knowles, MD, PhD

MRI Microstructure Mapping to Improve Detection of Focal Cortical Dysplasia
PI: Juliet Knowles, MD, PhD

Study of Oral MC-1 for the Treatment of Patients with PNPO Deficiency

A Natural History Study of Rare Neurogenetic Disorders
PI: Rebecca Levy, MD, PhD

A Retrospective Case Series of Timothy Syndrome
PI: Rebecca Levy, MD, PhD

SLC13A5 Deficiency:A Prospective Natural History Study
PI: Brenda Porter, MD, PhD

Pediatric Epilepsy Surgery: Decision-Making Survey in Patients with Tuberous Sclerosis
PI: Brenda Porter, MD, PhD

Preventing Epilepsy Using Vigabatrin in Infants with Tuberous Sclerosis Complex (PREVeNT Trial)
PI: Brenda Porter, MD, PhD

Stopping Tuberous Sclerosis Complex Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study (TSC-STEPS)
PI: Brenda Porter, MD, PhD

Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) Determinants in Tuberous Sclerosis Complex (TSC)
PI: Brenda Porter, MD, PhD

Project BIG: The Stanford Brain Immune Gut Research Initiative
PI: Keith Van Haren, MD

Biobank for Neuroinflammatory Disorders
PI: Keith Van Haren, MD

A phase 1-3, Double Bind, Randomized Placebo- Controlled Study to Evaluate the Efficacy, Safety, PharmacoKinetics and Pharmacodynamics Intrathecally Administered ION373 in Patients with Alexander Disease (Gene Transfer)
PI: Keith Van Haren, MD

A phase 3 Study of Lenti-D Drug Product After Myeloblative Conditioning Using Busulfan and Fludarabine in Subjetcs 17 Years of Age and Under With Cerebral Adrenoleukodystrophy (CALD) (BMT/GeneTransfer)
PI: Keith Van Haren, MD

The Effect of Vitamin D3 on Markers of Oxidative Stress in Boys with X-Linked Adrenoleukodystrophy (ALD)
PI: Keith Van Haren, MD

New Diagnostic Approaches in Leukodystrophy - The Myelin Disorders Biorepository and Natural History Project
PI: Keith Van Haren, MD

Continuation of the analysis of Cytokine Modulation with Tecfidera in Human Immune Cell Subsets using High Dimensional Flow Cytometry and CYTOF Mass Spectrometry
PI: Lawrence Steinman, MD

Single Cell RNA-seq and CITE-seq on B cells in the peripheral blood and CSF of MS patients prior and during therapy with ATA-188
PI: Lawrence Steinman, MD

Neonatal Seizure Registry

High Frequency Oscillations in Neonates

Neonatal Seizure Registry- Developmental functional Evaluation (NSR-DEV)

Continued Anticonvulsants After Resolution of Neonatal Seizures: A Patient-centered Comparative Effectiveness Study

Temporal-spatial quantification of neonatal seizure burden caused by arterial ischemic stroke

MRI and EEG findings in preterm neonates with HIE

Vascular Effects of Infection in Pediatric Stroke (VIPS II) Study
PI: Sarah Lee, MD

Stanford Children's Health Pediatric Stroke Database
PI: Sarah Lee, MD

International Pediatric Stroke Registry: Risk Factors and Outcome Observational Study
PI: Sarah Lee, MD

Seizures and Children 's Outcomes after Stroke (SCOUTS)
PI: Sarah Lee, MD

Leducq Trans-Atlantic Network of Excellence On Circadian Effects in Stroke (CIRCA-Stroke)
PI: Sarah Lee, MD

Focal Cerebral Arteriopathy Steroid Trial Pediatric Comparative Effectiveness Trial (FOCAS)
PI: Sarah Lee, MD

acutE Perfusion Imaging in Childhood LVO (EPIC-LVO): A Prospective Neuroimaging Pilot Study
PI: Sarah Lee, MD

Practices in the Evaluation of Pediatric Brain Death

Critical Care EEG Monitoring Research Consortium

Creation and Development of Pediatric Neurocritical Care Database

MEK Inhibitor Mirdametinib (PD-0325901) in Patients With Neurofibromatosis Type 1 Associated Plexiform Neurofibromas
PI: Cynthia Campen, MD

A Phase 2b Trial of MEK ½ Inhibitor (MEKi) PD-0325901 in Adult and Pediatric Patients with Neurofibromatosis Type 1 (NF1)-Associated Inoperable Plexiform Neurofibromas (PNs) that are Causing Significant Morbidity
PI: Cynthia Campen, MD

Developing Evidence-Based Criteria for Initiating Treatment for NF1-Associated Optic Pathway Glioma:  A Natural History Observational Study
PI: Cynthia Campen, MD

Neuroimaging Correlates of Neurocognitive Deficits in Children with NF1
PI: Cynthia Campen, MD

Optic Disc Drusen in children
PI: Shannon Beres, MD