Neurology & Neurological Sciences News
Depression can be a very serious problem after stroke. This study will help us develop new and better treatments for those who aren't completely treated by current anti-depressants.
Congratulations, Chinyere Agbaegbu Iweka, PhD, on receiving a Simons Foundation Independence Award for her work "Circadian regulation of immune cell metabolism and the effect on cognitive flexibility in the aging brain"
Congratulations, Cellas Hayes, PhD on your 2023 Stanford Postdoc JEDI Champion award! The JEDI Champion Awards are a recognition of current Stanford postdoctoral scholars who have championed initiatives, activities, or efforts that advance justice, equity, diversity, & inclusion at Stanford and beyond.
Lawrence Steinman, MD and his collaborators recently identified a molecule that could be targeted by drug developers to treat ALS. The protein, alpha 5 integrin, is related to another integrin (alpha 4), a type of protein that helps immune cells move and bind to their surroundings like Velcro.
Welcome Anthony Omuro, MD
The Department of Neurology and Neurological Sciences would like to welcome our newly appointed chair, Antonio Omuro, MD, who will join our department in February 2024.
A massive study of medical and genetic data shows that people with a particular version of a gene involved in immune response had a lower risk of Alzheimer’s and Parkinson’s disease.
Which comes first: Depression or dementia? A team of scientists led by Victor Henderson, MD found that the risk of dementia more than doubles for people previously diagnosed with depression.
Congratulations to Juliet Knowles, MD, PhD for receiving a McKnight Foundation 2023 Neurobiology of Brain Disorders Award for her work "Neuron-to-OPC synapses in adaptive and maladaptive myelination"
The Certificate of Special Congressional Recognition
Jeff Dunn, MD was awarded The Certificate of Special Congressional Recognition by Rep. Mike Thompson for advancing the care and research of Multiple Sclerosis.
Congratulations, Yi Li, MD, PhD, for receiving an American Epilepsy Society Junior Investigator Award for her work titled "Genetic impact of women with epilepsy on their children’s cognitive outcome".
Helen Bronte-Stewart discusses Quantitative Digitography (QDG), a unique, remote technology that provides health care providers with quantitative, validated measures of all motor symptoms of Parkinson’s disease. Data from alternating finger tapping on the digitography device is analyzed in our HIPAA-compliant cloud-based service, and metrics are available to the provider in the electronic medical record in real time.
June is Migraine Awareness Month. WebMD Podcast. Dr. John Whyte sits down with two migraine experts, Dr. Cynthia E Armand, clinical director of Montefiore Headache Center and fellowship director of the Montefiore Headache Program, and Dr. Addie Peretz, board-certified neurologist and clinical assistant professor at Stanford Medicine, to discuss diagnostic criteria, cardiovascular risks, the impact of social determinants of health, support during reproductive years, and new treatment options to empower long-term migraine sufferers.
Can Young-Blood Infusions Reverse the Aging Process? A diverse group of researchers are attempting to identify anti-aging components in blood that may help our brains remain younger and fitter as we age.
The goal of the Moonshot initiative -- named after President John F. Kennedy's audacious 1961 vow to put a human on the moon -- is to cut the death rate from cancer by at least 50% over the next 25 years. How? By bridging chasms between scientific research and therapeutic solutions, beginning with a focus on cancer's most deadly forms.
2 million young adults suffer from strokes ever year. Maarten Lansberg, MD, PhD, professor at the Stanford Stroke Center, provides insight about risk factors.
Helen Bronte-Stewart is a neurologist and an expert in movement disorders, like Parkinson’s. She says new approaches, such as closed-loop deep-brain stimulation, and new digital health technologies that chart subtle changes in movement are reshaping the field, leading to new understandings and new treatments for this once-untreatable disease. To modulate behavior, you first have to measure it, Bronte-Stewart tells host Russ Altman. It’s the future of movement disorders in this episode of Stanford Engineering’s The Future of Everything podcast.
In the first of its kind, a group of investigators at Stanford Healthcare mapped the pathways for seizure propagation through the brain’s switchboard (thalamus) in patients with presumed refractory temporal lobe epilepsy by recording simultaneously from multiple sites within this structure. Their findings - now published by Teresa Wu and colleagues in Brain – reveals a novel and surprising finding: In more than half of the patients, seizures do not spread the way we thought they did! They concluded that personalized targeting of the thalamus for neuromodulation in each patient may lead to better treatment outcomes in these patients.
In an enormous leap forward in the understanding of Parkinson’s disease (PD), researchers have discovered a new tool that can reveal a key pathology of the disease: abnormal alpha-synuclein — known as the “Parkinson’s protein” — in brain and body cells. The breakthrough, announced last night as it was published in the scientific journal The Lancet Neurology, opens a new chapter for research, with the promise of a future where every person living with Parkinson’s can expect improved care and treatments — and newly diagnosed individuals may never advance to full-blown symptoms.
New research shows that Multiple Sclerosis may be caused by Epstein Barr virus infection. Learn more in this informative Grand Rounds lecture at the Seattle Science Foundation by Jeffrey Dunn, MD.
Three years after the official declaration of a pandemic, 65 million people - one in 10 who had Covid-19 - still have symptoms. Some are so ill they are yet to return to work. Michelle Monje-Deisseroth, MD, PhD and other researchers around the world try to unravel the cause behind long COVID which is associated with around 200 symptoms including persistent cognitive impairment.
A genetic risk factor found virtually exclusively among people of at least partial African ancestry substantially boosts the risk of incurring Alzheimer’s disease — but only sometimes.
The Phil and Penny Knight Initiative for Brain Resilience is proud to announce the recipients of its inaugural 2022 Innovation and Catalyst Grants.
In this newsletter, we hope to review the many facets of how diversity and inclusion are actively being promoted throughout the culture and mission of our Department of Neurology. We encourage participation and engagement by all!
NBC's Today Show highlights Dr. Mitchell Miglis and the Stanford Autonomic Division's ongoing research efforts in Long-COVID. Dr. Miglis' team is currently recruiting patients who developed Postural Tachycardia Syndrome (POTS) after COVID, as well as those who had COVID and fully recovered, and those who never had COVID, for an NIH-sponsored study to better understand the mechanisms of Long-COVID dysautonomia. If interested, please email: firstname.lastname@example.org.
Paul George taps into the bioelectrical language of the injured brain to reawaken the healing potential of neural stem cells. Inspired by his patients, he looks for innovative strategies that may one day help patients recover from neurodegenerative diseases such as stroke. In this episode, Iris Kulbatski from The Scientist’s Creative Services Team spoke with George to learn more about what being a scientist means to him.
Brain fog isn’t like a hangover or depression. It’s a disorder of executive function that makes basic cognitive tasks absurdly hard.
Lab-grown clusters of human brain cells integrate so well into young rats’ brains they enable researchers to study neurodevelopmental disorders’ molecular and circuit underpinnings.
Join Chris Hemsworth and our very own Sharon Sha, MD, MS, in exploring the boundaries of human potential in #LimitlessWithChrisHemsworth, a Disney+ Original series from National Geographic, streaming November 16 on Disney+.
Stanford researchers Rob Cowan and Danielle DeSouza, collaborating with colleagues at the University of Maryland recently published in the Journal of Neuroscience a ground-breaking study looking at fMRI correlates of migraine chronification in subsets of patients with episodic and chronic migraine. The study identified, for the first time, distinct subgroups within the migraine population which may lead to novel biomarkers and more patient-centered treatment strategies.
Women with epilepsy experience more anxiety and depression symptoms during and after pregnancy than other women, according to a new study led by researchers at Stanford Medicine.
Stanford Medicine researchers tracked memory formation in real time, watching how muscle memory is created.
What can we all be doing in the here and now to keep our brains in shape? Stanford Medicine neuroscientist Tony Wyss-Coray, PhD, discusses his findings in the field of cognitive rejuvenation.
Q&A with Sharon Sha MD, MS: Dr. Sha weighs in on how the brain controls our movements, behavior, thoughts and memories -- and how that changes when things go awry.
Listen to Niushen Zhang, MD, FAHS, Division Chief of the Stanford Headache division and Clinical Assistant Professor of Neurology & Neurological Sciences, discuss lifestyle modifications including aerobic exercise, sleep quality, behavioral therapies, nutrition and other strategies to combat migraine.
The funding, from Cancer Grand Challenges, will help the researchers address difficult problems in cancer prevention, treatment-resistant cancers and therapies for pediatric solid tumors.
Researchers found that damage to the brain’s white matter after COVID-19 resembles that seen after cancer chemotherapy, raising hope for treatments to help both conditions.
Researchers, led by Michael Greicius, MD, MPH have discovered that a rare mutation inherited with the APOE4 gene variant protects against Alzheimer's, shedding new light on ways to counteract high-risk genes for the disease.
Katrin Andreasson discusses how immune cells can cause harmful brain inflammation and contribute to the development of neurodegenerative diseases like Alzheimer’s disease.
Excellence in Workplace Award
Congratulations, Rebecca Miller-Kuhlmann, MD, on your Excellence in Workplace Award! This award is presented to a physician whose efforts demonstrably improves the “practice life” and satisfaction of providers in the delivery of clinical care. This individual strives to enhance work-life balance and highlights the importance of wellness and fulfillment at work.
Congratulations, Juliet Knowles, MD, PhD, on your 2022 McCormick Faculty Award. This award was established to support the advancement of women in medicine and/or medical research directly, or by supporting the mentoring, training and encouragement of women pursuing the study of medicine, in teaching medicine, and engaging in medical research.
Even a mild SARS-CoV-2 infection can cause inflammation that disrupts neural communication, says Stanford neurologist Michelle Monje. Her concern is that Covid-19 may leave millions dealing with cognitive problems, from a loss of mental sharpness to lapses in memory, that prevent them from returning to their previous level of function.
Scientists have been trying to unravel the mysteries of why memory diminishes with age for decades. Now they have discovered a possible remedy — cerebrospinal fluid from younger brains.
NIH U19 grant award
Congratulations to Drs. Michelle Monje, Mike Lim, and Reena Thomas for their successful U19 grant award from the NIH. In a collaborative effort with the Harvard brain tumor program, this grant will allow for the evaluation of multiple novel therapeutics for patients afflicted by glioblastoma brain tumors. The correlative studies proposed will also advance precision medicine and our scientific understanding of the disease to ultimately improve treatment of adult glioblastoma brain tumors. This grant also means that Stanford has become a member of the prestigious new National Cancer Institute “Glioblastoma Therapeutic Network”, a national clinical trial consortium for adult brain tumors that will increase the cutting edge clinical trial options for Stanford patients.
ACNS Distinction in Service Award
Congratulations, Dr. Courtney Wusthoff, the inaugural recipient of the ACNS Distinction in Service Award! This award was created by the American Clinical Neurophysiology Society (ACNS) to recognize a mid-career ACNS member who has demonstrated outstanding service to the field of clinical neurophysiology at the institutional or national level.
2022 ACNS Young Investigator Travel Award
Thomas Hirschauer MD, PhD, Clinical Neurophysiology/Intraoperative Neuromonitoring Fellow at Stanford, received the ACNS Young Investigator Travel Award for his work "Multimodal Intraoperative Neurophysiologic Monitoring for the Detection of Cerebral Ischemia During Carotid Endarterectomy"
Second cohort of CZ Biohub Investigators includes 33 Stanford faculty
Dr. Katrin Andreasson was selected from nearly 700 applicants as a Chan Zuckerberg Biohub Investigator. The Investigator Program, open to faculty members at Stanford University, UC San Francisco, and UC Berkeley, awards $1 million in unrestricted funds over five years to each Investigator, with the goal of building engaged, collaborative communities of Bay Area scientists to undertake creative and innovative research that will help solve the biggest challenges in biomedicine.
Stanford University researchers who study three-dimensional structures of biological molecules, aggressive brain cancers and how to heal diseased hearts are among 33 scientists from 21 institutions announced as new Howard Hughes Medical Institute investigators. The Stanford faculty members are Kristy Red-Horse, associate professor of biology at the School of Humanities and Sciences, Rhiju Das, associate professor of biochemistry, and Michelle Monje, associate professor of neurology.
Dunlevie Family University Fellow in Undergraduate Education
Congratulations to Paul Graham Fisher, MD, Professor of Neurology & Neurological Sciences for his reappointment to another 5 year term as Dunlevie Family University Fellow in Undergraduate Education. Fisher teaches the popular undergraduate classes “Cancer Epidemiology” and “The Human Organism” in Human Biology. He was the Bing Director of Human Biology from 2012 through 2019.
Kelley M. Skeff GME Professionalism Award
Congratulations, Nick Murray, MD for winning the inaugural Kelley M. Skeff GME Professionalism Award! This award, named in honor of Dr. Kelley Skeff (prior Stanford internal medicine residency program director and internationally known leader in education), recognizes high levels of excellence and compassion in professional behavior through collaborative work with colleagues, faculty and staff from across the institution. Congrats, Dr. Murray!
Oscar Salvatierra Award
Congratulations to Jeffrey Dunn, MD, inaugural award winner of the Oscar Salvatierra Award for Exceptional Service to Stanford medical students and the Stanford University School of Medicine. Dr. Dunn built the Neurology clerkship into a model of national excellence and the highest rated clerkship in the SOM for more than a decade, inspiring more than a thousand medical students during his tenure.
Congratulations to Reena Thomas, MD, PhD for receiving the Stanford Award for Excellence in Promotion of Diversity and Societal Citizenship. This award was established to recognize individuals that have made significant contributions to the promotion of the principles of diversity and societal citizenship at the Stanford School of Medicine.
Stanford neuro-oncologist Michelle Monje teamed up with Craig Thomas at the National Center for Advancing Translational Sciences and Kathy Warren from NCI (now at DFCI) to perform high-throughput drug screening of patient-derived cultures of diffuse intrinsic pontine glioma, the leading cause of brain tumor-related death in children. The study, led by MD PhD student and future neurologist Grant L. Lin, uncovered a promising two-drug combination that shows benefit in preclinical studies and will advance to clinical trial soon. The mechanism of drug-drug synergy was determined to be metabolic collapse, highlighting a key avenue for future strategies in this lethal childhood brain cancer. Stanford neurologist Kati Andreasson’s lab contributed importantly to the metabolic mechanistic studies.