Bio

Clinical Focus


  • Sleep Medicine
  • Autonomic Disorders
  • Neurology

Professional Education


  • Board Certification, Sleep Medicine, American Board of Psychiatry and Neurology (2013)
  • Board Certification: Neurology, American Board of Psychiatry and Neurology (2011)
  • Fellowship, Stanford University Medical Center, Sleep Medicine (2013)
  • Fellowship, Beth Israel Deaconess Medical Center/Harvard Medical School, Autonomic Disorders and Clinical Neurophysiology (2012)
  • Residency, New York University, Neurology (2011)
  • Internship, Washington Hospital Center/Georgetown University (2008)
  • Medical Education:University of Florida College of Medicine (2007) FL
  • Fellowship:Stanford University Medical Center (2013) CA
  • Fellowship:Beth Israel Deaconess Medical Center (2012) MA
  • Internship:Washington Hospital Center (2008) DC
  • Residency:New York Medical College (2011) NY

Research & Scholarship

Current Research and Scholarly Interests


Sleep disorders in patients with postural tachycardia syndrome, REM behavior disorder, autonomic dysfunction in sleep

Publications

Journal Articles


  • Kleine-Levin Syndrome: A Review Nature and Science of Sleep Miglis, M., Guilliminault, C. 2014 ; 6: 19-26
  • Seropositive myasthenia and autoimmune autonomic ganglionopathy: Cross reactivity or subclinical disease? AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL Miglis, M. G., Racela, R., Kaufmann, H. 2011; 164 (1-2): 87-88

    Abstract

    Autoimmune autonomic ganglionopathy (AAG) and myasthenia gravis (MG) are both autoimmune channelopathies mediated by antibodies directed against nicotinic acetylcholine receptors. While both diseases target acetylcholine receptors, skeletal muscle and ganglionic receptor subtypes have key immunologic and genetic distinctions, and reports of patients with both AAG and MG are rare. We report a patient with antibody-confirmed AAG and elevated levels of ACh binding antibodies that did not meet clinical or electrodiagnostic criteria for MG. We presume that his skeletal muscle nAChR seropositivity was a false positive, perhaps due to the cross reactivity of the patient's ganglionic nAChR antibodies with skeletal nAChR subtypes.

    View details for DOI 10.1016/j.autneu.2011.06.005

    View details for Web of Science ID 000295346500013

    View details for PubMedID 21745762

  • Intracranial Venous Thrombosis After Placement of a Lumbar Drain NEUROCRITICAL CARE Miglis, M. G., Levine, D. N. 2010; 12 (1): 83-87

    Abstract

    Lumbar drains are frequently used in clinical neuroscience and are often managed in the neurointensive care unit. Complications are generally rare, and intracranial venous thrombosis (IVT) and infarction has not been reported.We report the case of a 45-year-old woman who developed a cerebrospinal fluid (CSF) leak after spinal surgery. Fifteen hours after placement of a lumbar drain she developed pure alexia and color agnosia caused by left lateral sinus thrombosis with hemorrhagic infarction in the posterior inferior left temporal lobe. We review the literature on the association of IVT with injury to the spinal dura, and we propose a mechanism whereby the lumbar drain may facilitate its development.We found 29 cases in which spinal dural injury was followed by IVT. The association is not coincidental, because nearly all cases were associated with post-dural puncture headache, which occurs in only a minority of cases of dural puncture. Injury to the spinal dura alters the distribution of craniospinal elasticity causing profound intracranial CSF hypotension on assuming the erect posture. This causes acute dilation of cerebral veins resulting in both orthostatic headache and venous stasis. We propose that placement of the lumbar drain and elevation of the head of the bed aggravated intracranial CSF hypotension and facilitated IVT.When a lumbar drain is placed for treatment of a spinal CSF leak, the patient should remain flat in bed. Any patient with post-dural injury headache that intensifies after an initial plateau, persists for longer than a week, or loses its orthostatic character should be evaluated for intracranial sinus or venous thrombosis.

    View details for DOI 10.1007/s12028-009-9278-9

    View details for Web of Science ID 000275742800015

    View details for PubMedID 19834826

  • A piece of my mind. Annie. JAMA Miglis, M. 2009; 306 (18): 1960-1.

    View details for DOI 10.1001/jama.2011.1627

  • Effect of taurine on platelets and the plasma coagulation system PLATELETS Miglis, M., Wilder, D., Reid, T., Bakaltcheva, I. 2002; 13 (1): 5-10

    View details for Web of Science ID 000173601100001

    View details for PubMedID 11918831

Books and Book Chapters


  • Right sided headache Case Based Neurology Miglis, M., Graber, J. Demo. 2013; 1: 261-5

Presentations


  • Sleep Disorders in Patients with Postural Tachycardia and Ehlers-Danlos Syndrome

    Sleep Medicine Grand Rounds

    Time Period

    1/8/2013

    Presented To

    Weill Cornell Medical Center

    Location

    New York, NY

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