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Christopher Lock
Clinical Associate Professor, Neurology & Neurological Sciences
Print Profile
Email Profile
Bio
Bio
Publications
Clinical Focus
Multiple Sclerosis
Neuroimmunology
Clinical Neurophysiology
Academic Appointments
Clinical Associate Professor,
Neurology & Neurological Sciences
Administrative Appointments
Clinical Trials Director, Stanford Multiple Sclerosis and Neuroimmunology Program (2015 - Present)
Member, SHC Pharmacy and Therapeutics Specialty Drug Sub-Committee (2016 - 2017)
Honors & Awards
Entrance Scholarship, Westminster Hospital Medical School, London, UK (1974)
Neuroimmunology Fellow, National Multiple Sclerosis Society (1997-2000)
Boards, Advisory Committees, Professional Organizations
Director, San Francisco Neurological Society (2024 - Present)
Board Member, California Neurological Society (2023 - Present)
Member, American Academy of Neurology (1994 - Present)
Professional Education
Residency: Stanford University Dept of Neurology (1997) CA
Board Certification: American Board of Psychiatry and Neurology, Neurology (2020)
Fellowship: Stanford University Neuroimmunology and Multiple Sclerosis Fellowship (2000) CA
Internship: Stanford University Internal Medicine Residency (1994) CA
Medical Education: Westminster Medical School (1980) England
Contact
Academic
lock@stanford.edu
Clinical (Primary)
This is the primary clinic for this clinical provider. For additional clinical locations and information, please visit the link(s) listed below in the 'Additional Clinical Info' section.
Stanford Neuroscience Health Center
213 Quarry Rd
MC 5957 Fl 2
Palo Alto CA 94304
Tel: (650) 723-6469
Fax: (650) 498-6045
Additional Clinical Info
Stanford Health Care
Links
Curriculum Vitae DOC
NIH Biosketch PDF
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Publications (30)
All Publications
(30)
Featured Publications
(15)
Journal Articles
(22)
Conference Proceedings
(8)
Profiles With Related Publications
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Marion S. Buckwalter, MD, PhD
Professor of Neurology and Neurological Sciences (Adult Neurology) and of Neurosurgery
Clinical Focus
Neurologic Critical Care, Neurocritical Care
Research Interests
The goal of the Buckwalter Lab is to improve how people recover after a stroke. We use basic and clinical research to understand the cells, proteins, and genes that lead to successful recovery of function, and also how complications develop that impact quality of life after stroke. Ongoing projects are focused on understanding how inflammatory responses are regulated after a stroke and how they affect short-term brain injury and long term outcomes like dementia and depression.
103
Total Publications
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Alma-Martina Cepika
Instructor, Pediatrics - Stem Cell Transplantation
47
Total Publications
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Yueh-hsiu Chien
Professor of Microbiology & Immunology
Research Interests
Contribution of T cells to immunocompetence and autoimmunity; how the immune system clears infection, avoids autoimmunity and how infection impacts on the development of immune responses.
108
Total Publications
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Edgar Engleman
Professor of Pathology and of Medicine (Immunology and Rheumatology)
Research Interests
Dendritic cells, macrophages, NK cells and T cells; functional proteins and genes; immunotherapeutic approaches to cancer, autoimmune disease, neurodegenerative disease and metabolic disease.
290
Total Publications
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C. Garrison Fathman
Professor of Medicine (Immunology and Rheumatology), Emeritus
Research Interests
My lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity. We have identified and characterized a gene (GRAIL) that seems to control regulatory T cell (Treg) responsiveness by inhibiting the Treg IL-2 receptor desensitization. We have characterized a gene (Deaf1) that plays a major role in peripheral tolerance in T1D. Using PBC gene expression, we have provisionally identified a signature of risk and progression in T1D.
326
Total Publications
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Jorg Goronzy
Professor of Medicine (Immunology and Rheumatology), Emeritus
487
Total Publications
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May Han, MD
Associate Professor of Neurology and Neurological Sciences (Adult Neurology)
Clinical Focus
Neuroimmunology, Multiple sclerosis (MS), Neuromyelitis optica, High risk MS, MS pregnancy, Clinical Neurophysiology
97
Total Publications
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Siddhartha Jaiswal
Associate Professor of Pathology
Clinical Focus
Transfusion Medicine, Genomics and Molecular Pathology, Anatomic and Clinical Pathology
Research Interests
We identified a common disorder of aging called clonal hematopoiesis of indeterminate potential (CHIP). CHIP occurs due to certain somatic mutations in blood stem cells and represents a precursor state for blood cancer, but is also associated with increased risk of cardiovascular disease and death. We hope to understand more about the biology and clinical implications of CHIP using human and model system studies.
76
Total Publications
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Patricia Jones
The Dr. Nancy Chang Professor, Emerita
Research Interests
Dr. Jones' research focused on genetic, molecular, and cellular mechanisms that regulate immune responses. She hHer most recent work was centered on the regulation of innate immune responses that are triggered by conserved microbial components. As these responses can be harmful they are highly regulated in their occurrence, magnitude, and duration. Her lab discovered a novel mechanism that negatively regulates innate responses, mediated by the phosphatase calcineurin.
31
Total Publications
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Tobias Lanz
Assistant Professor of Medicine (Immunology and Rheumatology)
34
Total Publications
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David B. Lewis
Naddisy Foundation Professor of Pediatric Food Allergy, Immunology, and Asthma
Clinical Focus
Primary Immunodeficiency, Pediatrics
Research Interests
My laboratory is focused on defining cellular and molecular mechanisms that limit T cell responses to vaccines and pathogens during normal early postnatal development and in cases of inherited genetic immunodeficiencies. We are also determinomg how these limitations in immunity can be overcome by using novel approaches for vaccine adjuvants for influenza vaccine and by using catalytically inactive Cas proteins for inducing endogenous gene expression.
179
Total Publications
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Jonathan Maltzman
Associate Professor of Medicine (Nephrology)
75
Total Publications
Publication Topics For This Person
4-Aminobutyrate Transaminase
Acute Disease
Amino Acid Sequence
Antibodies, Monoclonal
Antigen Presentation
Antigen-Presenting Cells
Antigens, CD
Aquaporin 4
Arthritis, Experimental
Arthritis, Rheumatoid
Astrocytes
Autoantigens
Autoimmune Diseases
Autoimmunity
Autopsy
Encephalomyelitis, Autoimmune, Experimental
Flow Cytometry
Histocompatibility Antigens Class II
Inflammation
Interferon-gamma
Interleukin-17
Lymphocyte Activation
Mice, Inbred C57BL
Mice, Knockout
Mice, Transgenic
Molecular Sequence Data
Multiple Sclerosis
Myelin Basic Protein
Oligonucleotide Array Sequence Analysis
T-Lymphocytes