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Discovery could limit toxic effect of chemo
Stanford researchers have found a way to predict who will suffer heart problems from a common breast-cancer drug, as well as identified an FDA-approved medication that could mitigate those side effects.
Molecular data categorizes breast cancers
Some breast cancers return decades later. Now, a researcher at Stanford, joined by collaborators at several other institutions, has subcategorized tumors to predict recurrence, guide treatment decisions and improve drug development.
Immune cell-based cancer diagnostics
Stanford scientists were able to engineer immune cells known as macrophages to detect and flag cancer in mice. The researchers hope the technique can be used for early cancer diagnostics in humans.
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A Legacy of Innovation
First synthesis of biologically active DNA in test tube
Nobel laureate Arthur Kornberg creates a strand of biologically active DNA, paving the way for studies of genetics.
First adult human heart transplant in the United States
Norman Shumway successfully transplants a heart into 54-year-old steelworker Mike Kasperak, who survives for 14 days.
First expression of a foreign gene implanted in bacteria by recombinant DNA methods
Geneticist Stanely Cohen transfers a foreign gene into bacterial cells, which then express the gene.
First successful human combined heart/lung transplant in the world (fourth attempted worldwide)
Mary Gohlke receives the world's first combined heart and lung transplant in a landmark operation led by surgeon Bruce Reitz.
Isolation of a gene coding for part of the T-cell receptor, a key to the immune system’s function
Immunologist Mark Davis characterizes the T-cell receptor, believed to regulate the body's response to infectious agents and cancerous diseases.
Isolation of pure hematopoietic stem cells from mice
Pathologist Irving Weissman isolates a rare mouse cell, known as the hematopoetic stem cell, which gives rise to all the cells of the blood and immune systems.
First use of gene expression profiling to predict cancer outcomes
Application and expansion of optogenetics, a technique to control brain cell activity with light
Bioengineer Karl Deisseroth and his team develop a technique known as optogenetics that allows them to genetically alter brain cell activity in mice with light.