Stanford Movement Disorders Center News
Women get Alzheimer’s more often than men: Five things the science tells us
Two-thirds of Americans living with Alzheimer's disease are women. Stanford Medicine neurologists Victor Henderson and Michael Greicius explain what science tells us about why, from the outsized impact of the APOE4 gene variant in women to the unresolved role of estrogen and hormone replacement therapy, and what still needs further study.
A Pacemaker for the Brain: Treating Parkinson's by Responding to the Brain's Rhythms in Real Time
Neurologist Helen Bronte-Stewart has spent two decades studying what goes wrong in the brains of people with Parkinson's disease. In a Q&A, she explains how that work led to adaptive deep brain stimulation (aDBS), an FDA-approved therapy that continuously monitors the brain's electrical activity and adjusts stimulation in real time, and what it means to finally see it reaching patients around the world after years of lab research.
Helen Bronte-Stewart Featured in CNN Article on Adaptive Deep Brain Stimulation for Parkinson's Disease
Helen Bronte-Stewart, MD, was recently featured in a CNN article on how adaptive deep brain stimulation is improving the lives of people with Parkinson's disease, told through the story of Keith Krehbiel, the first patient enrolled in the pivotal international clinical trial she led at Stanford.
Pioneering Adaptive Deep Brain Stimulation Technology for Parkinson’s Disease
Neurologist Helen Bronte-Stewart has led groundbreaking research that culminated in the FDA's recent approval of adaptive deep brain stimulation (aDBS), a personalized treatment for Parkinson’s disease. This innovative technology adjusts electrical pulses based on individual brain signals, offering a more effective and tailored approach to managing symptoms for millions affected by the condition.
Revolutionizing Parkinson's Care: QDG Health's 30-Second Test Transforms Treatment Paradigms
As the prevalence of Parkinson’s disease surges, QDG Health introduces an innovative health management system that leverages a simple 30-second finger-tapping assessment to deliver real-time, AI-informed insights into patient motor symptoms. Developed by Dr. Helen Bronte-Stewart at Stanford, this breakthrough technology promises to streamline clinical trials, enhance remote monitoring, and ultimately elevate the standard of care for individuals living with Parkinson's.
Why detecting the earliest biological signs of Parkinson’s disease is so crucial
Parkinson's disease is the second most common neurodegenerative disease, behind Alzheimer's disease, and affects nearly a million people in the United States. A new test can detect the biological signature of Parkinson’s disease before symptoms arise. Dr. Kathleen Poston explains why early diagnosis opens the door to better therapies.
Interview with Helen Bronte-Stewart, principal investigator, QDG
Helen Bronte-Stewart discusses Quantitative Digitography (QDG), a unique, remote technology that provides health care providers with quantitative, validated measures of all motor symptoms of Parkinson’s disease. Data from alternating finger tapping on the digitography device is analyzed in our HIPAA-compliant cloud-based service, and metrics are available to the provider in the electronic medical record in real time.
The future of movement disorders
Helen Bronte-Stewart is a neurologist and an expert in movement disorders, like Parkinson’s. She says new approaches, such as closed-loop deep-brain stimulation, and new digital health technologies that chart subtle changes in movement are reshaping the field, leading to new understandings and new treatments for this once-untreatable disease. To modulate behavior, you first have to measure it, Bronte-Stewart tells host Russ Altman. It’s the future of movement disorders in this episode of Stanford Engineering’s The Future of Everything podcast.
Parkinson's Disease Biomarker Found
In an enormous leap forward in the understanding of Parkinson’s disease (PD), researchers have discovered a new tool that can reveal a key pathology of the disease: abnormal alpha-synuclein — known as the “Parkinson’s protein” — in brain and body cells. The breakthrough, announced last night as it was published in the scientific journal The Lancet Neurology, opens a new chapter for research, with the promise of a future where every person living with Parkinson’s can expect improved care and treatments — and newly diagnosed individuals may never advance to full-blown symptoms.
Deep sequencing of sncRNAs reveals hallmarks and regulatory modules of the transcriptome during Parkinson’s disease progression
A study led by Andreas Keller, visiting faculty at Stanford, along with Kathleen Poston and Tony Wyss-Coray, reports the longitudinal profiling of circulating small noncoding RNAs in the blood of patients with Parkinson's and identifies several microRNAs as potential diagnostic and prognostic biomarkers.
How hacking the human heart could replace pill popping
A new generation of “smart” implantable devices could replace traditional medication to treat a range of chronic conditions, including cardiac disease. Twitter: @geditorial_uk
Stanford announces new Lewy Body Dementia (LBD) Research Center of Excellence
In December 2017 researchers from across the country joined in the first-ever comprehensive network of research centers to conduct LBD clinical trials, provide community outreach, and expand professional continuing medical education. Representing 24 of medicine’s most prestigious academic medical research centers, these Research Centers of Excellence will help to streamline and standardize LBD science while connecting patients and families with the latest opportunities to participate in LBD clinical trials.
Parkinson's patients take to the dance floor
Finding the rhythm is half the fun of dancing, but it takes a little more effort when your body is wracked by Parkinson's Disease. But in a brand new dance studio at Stanford's Neuroscience Health Center, patients are able to hit the floor with the help of professional dancer Damara Vita Ganley and a program designed to help them get in touch with their bodies.
