Research at the Stanford Stroke Center

The Stanford Stroke Center has consistently been one of the most prolific stroke research groups in the United States; faculty members have published more than 700 manuscripts based on clinical stroke research, as well as hundreds of basic science studies; the Center has maintained continuous NIH grant support for 28 years. Stroke Center faculty members have authored more than 25 national and international clinical guideline statements. Stanford has pioneered major advances in medical therapies for treating and preventing stroke, neurosurgical techniques for stroke prevention, and novel interventional neuroradiologic procedures for stroke patients. The Center developed the RAPID stroke imaging platform and designed and coordinated the three NIH-funded DEFUSE studies, which led to demonstrating the efficacy of both intravenous thrombolysis and endovascular thrombectomy in imaging-selected patients who presented late after stroke onset. The Neurocritical Care Program has made key advances in the diagnosis of intracerebral hemorrhage and the prognosis of coma. Stanford neuroscientists have helped clarify the basic mechanisms of stroke-induced brain injury and have pioneered several new imaging techniques that facilitate the identification of salvageable ischemic brain tissue in patients presenting with an acute stroke. Stroke recovery research, including participation in multiple early-phase clinical stem cell therapy trials and development of a new line of stem cells, has also been a focus area.


Research Programs