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About Our Research
Anesthesiology has been undergoing major changes globally, expanding roles beyond the operating room in offering high quality personalized services in peri-operative health, pain management, critical care and other medical disciplines. Research has been a major factor underlining these changes and will continue to be an essential force driving the evolution of the specialty.
Stanford Anesthesia research includes a wide spectrum of programs in basic, translational, clinical, health service, and medical education areas. Project fields range from subcellular mechanisms of anesthesia, pain, and opioid addiction, tissue/organ injury, novel anesthesia agents, techniques and devices, treatment effectiveness, epidemiology, patient safety, health economics and other areas. Interdisciplinary collaborations are increasingly a feature. Our department has been among the top five NIH funded anesthesia departments since 2011, with current external research grants and contracts totaling $17 million annually.
Stanford Anesthesia pays special attention to research training for the next generation of anesthesiologists and has established a research-training continuum bridging between medical student and faculty stages. We place special emphasis on supporting the residency-fellowship-junior faculty period. A key part of this support is the Fellowship in Anesthesia Research and Medicine (FARM) program and our two NIH supported T32 training grants.
In the Press
- – LWW
Microglial Modulation as a Target for Chronic Pain: From... : Anesthesia & Analgesia
With a widespread opioid epidemic and profound biopsychosocial implications, chronic pain is a multifaceted public health issue requiring urgent attention. The treatment of chronic pain is particularly important to anesthesiologists given our unique role as perioperative physicians and pain medicine specialists.
- – Scope
Make it stop: New frontiers in pain research offer hope - Scope
A Stanford anesthesiologist is working to understand why pain becomes agonizing and chronic by examining the role of cells known as microglia.
- The Bertaccini, Gross, Heifets and MacIver Laboratories recently characterized some novel potential anesthetics that were developed from molecular models of anesthetic binding sites on GABA receptors. These new anesthetics produce rapid and stable anesthesia in rodents but were without the hemodynamic and respiratory depression produced by propofol/barbiturates. Our first report of this work garnered a ‘best in show’ award and the International Anesthesia Research Society annual meeting.
- Tawfik finally joins Twitter! Follow her to learn more about the work her lab is doing trying to understand the switch from acute to chronic pain! @TawfikLab
- Is overlapping surgery associated with worse outcomes for patients? Assistant Professors Eric Sun and Bassam Kadry as well as current resident (CA-3) Chris Rishel recently published a paper in JAMA on this topic. Link to paper: https://jamanetwork.com/journals/jama/fullarticle/2725689.
- The Eric Gross Lab is developing precision medicine for anesthesia and analgesia through a NIH NIGMS R35 grant. We are developing tools to study the alcohol flushing response and the impact of ALDH2*2 (rs671) on anesthesia and analgesia.
- E-cigarette addiction is the newest epidemic facing the United States, particularly amongst the youth of our society. The Eric Gross Lab is looking at how genetics coupled with e-cigarette exposure may effect the cardiopulmonary system.