SCI Innovation Award

innovation award

Award information

In keeping with its core mission, the Stanford Cancer Institute has been dedicated to advancing cancer research through the SCI Innovation Awards program since 2013. The awards support projects focused on accelerating basic, translational, clinical, and population-based cancer research and projects focused on specific types of cancer, such as breast, colon, lung, pancreas, prostate, melanoma, and sarcoma cancers. We strongly encourage candidates of diverse backgrounds, women, and young investigators to apply.

Award Categories

  • Stanford Cancer Institute Nodal Awards - $50,000
    The SCI offers a funding mechanism that aims to catalyze the planning and execution of multi-PI grants from the National Cancer Institute, including R01s, P01s, and SPOREs. The funds are intended to be used to obtain proof of concept data and support planning activities.   
  • Stanford Cancer Institute Cancer Innovation Award - $50,000
    The SCI offers awards to support projects focused on the acceleration of basic, translational, clinical and population-based cancer research and collaborations leading to multi PI peer-reviewed funding.
  • Stanford Cancer Institute Pancreatic Cancer Innovation Award - $50,000
    The SCI offers awards leading to a greater understanding of pancreatic cancer, with the ultimate goal of improving the prevention or treatment of pancreatic cancer.
  • SCI Women’s Cancer Center Innovation Award - $50,000
    With support from the fundraising efforts of Under One Umbrella, the SCI and the Stanford Women’s Cancer Center offer awards for research projects related to women’s cancers.
  • Shmunis Family Innovation Awards in Cancer Therapeutics - $50,000
    The SCI is pleased to offer these new awards focused on cancer drug development and cancer therapeutics.  We encourage proposals that are “high-risk, high-reward drug development projects,” which enable researchers to develop therapeutic modalities that could lead to early-phase clinical trials and transformative new treatments for patients.
  • Behar Innovation Awards in Sarcoma Research - $50,000
    The SCI offers awards leading to a greater understanding of sarcoma, with the ultimate goal of improving the prevention or treatment of sarcoma.
  • Michael Toshio Cure for Cancer Catalyst Award - $100,000
    The SCI offers awards to support the development of investigator-initiated trials (IITs) that lead to transformative new treatments and interventions for patients. 

Project Priorities

  • Bold and creative research projects
  • Research related to cancer health equity
  • Research related to breast, colon, lung, pancreas, prostate, melanoma, and sarcoma
  • Multi-disciplinary collaboration, including collaborations involving Stanford faculty beyond the School of Medicine or inter-programmatic collaborations across the seven SCI research programs
  • Investigator-initiated clinical trial
  • Plans for submission of an external peer-reviewed (preferably NCI) application 

October 2024 Awardees

Stanford Cancer Institute Cancer Innovation Award

SCI Women’s Cancer Center Innovation Award

Shmunis Family Innovation Awards in Cancer Therapeutics

Michael Toshio Cure for Cancer Catalyst Award

  • Modulation of GVHD through the EPO/EPOR axis

    Robert Negrin, MD, professor of medicine (blood and marrow transplantation and cellular therapy), and Edgar Engleman, MD, professor of pathology and of medicine (immunology and rheumatology), received a Michael Toshio Cure for Cancer Catalyst Award.

Prior Awardees

SCI Innovation Awards

SCI Nodal Award

SCI Pancreatic Cancer Innovation Award

  • Rewiring RAS pathway mutations to activate programmed cell death in pancreatic cancer

    Gerald Crabtree, MD, David Korn, MD, Professor of Pathology and professor of developmental biology, and Nathanael Gray, PhD, Krishnan-Shah Family Professor of chemical and systems biology, were awarded an SCI Pancreatic Cancer Innovation Award for their project, “Rewiring RAS pathway mutations to activate programmed cell death in pancreatic cancer.”

SCI Women’s Cancer Center Innovation Award

Behar Innovation Award in Sarcoma Research

SCI Innovation Award

  • Degron-controlled base editors for massively scalable gene variant screens

    A $50,000 SCI Women's Cancer Center Innovation Award was awarded to Paul Blumenthal, MD, MPH, professor of obstetrics and gynecology, and his co-investigators Emily McClung, MD, clinical assistant professor of obstetrics & gynecology, and Michelle Khan, MD, MPH, clinical associate professor of obstetrics & gynecology, for their proposal entitled “Innovating for treatment of cervical pre-cancer: Novel use and application of trichoroacetic acid (TCA) to treat cervical dysplasia with an ultimate focus on low-resource settings.”

  • High-throughput engineering of receptors and signaling adapters to program anti-tumor macrophages

    A $50,000 SCI Women's Cancer Center Innovation Award was awarded to Paul Blumenthal, MD, MPH, professor of obstetrics and gynecology, and his co-investigators Emily McClung, MD, clinical assistant professor of obstetrics & gynecology, and Michelle Khan, MD, MPH, clinical associate professor of obstetrics & gynecology, for their proposal entitled “Innovating for treatment of cervical pre-cancer: Novel use and application of trichoroacetic acid (TCA) to treat cervical dysplasia with an ultimate focus on low-resource settings.”

  • Elucidating mechanisms of lymph node metastatic tolerance in high-risk resectable cholangiocarcinoma

    A $50,000 SCI Innovation Award was awarded to Lipika Goyal, MD, associate professor of medicine (oncology), Edgar Engleman, MD, professor of pathology and of medicine (immunology and rheumatology), Daniel Delitto, MD, PhD, assistant professor of surgery (general surgery), and Gregory Charville, PhD, assistant professor of pathology, for their proposal titled “Elucidating mechanisms of lymph node metastatic tolerance in high-risk resectable cholangiocarcinoma.”

  • Regulation of mRNA 3’ end formation by recurrent RNA splicing factor mutations

    A $50,000 SCI Women's Cancer Center Innovation Award was awarded to Fauzia Riaz, MD, clinical assistant professor of medicine (oncology), and Candice Thompson, MD, clinical assistant professor of surgery, and their collaborator Melinda Telli, MD, associate professor of medicine (oncology), for their proposal “Circulating tumor-DNA detection in early stage triple negative and HER2-positive breast cancer.”

  • Co-design of an educational intervention for melanoma prevention and awareness for teens

    A $50,000 SCI Innovation Award was awarded to Dawn Siegel, MD, clinical professor of dermatology, and Albert Chiou, MD, MBA, clinical associate professor of dermatology, for their proposal titled “Co-design of an educational intervention for melanoma prevention and awareness for teens.”

  • A synthetic GPCR platform for cell-based cancer therapy

    Alice Ting, PhD, professor of genetics, of biology, was awarded a $50,000 SCI Innovation Award for her proposal “A synthetic GPCR platform for cell-based cancer therapy.”

SCI Pancreatic Cancer Innovation Awards

  • Claudin-4-targeted imaging and readiothergnostics to treat pancreatic cancer

    A $50,000 SCI Pancreatic Cancer Innovation Award was awarded to Katherine Ferrara, PhD, professor of radiology, for her proposal “Claudin-4-targeted imaging and readiothergnostics to treat pancreatic cancer.”

  • Engineering of personalized medicine organoids for pancreatic ductal adenocarcinoma

    Sarah Heilshorn, PhD, director of the Geballe Laboratory for Advanced Materials (GLAM), professor of materials science and engineering, Calvin Kuo, MD, PhD, Maureen Lyles D'Ambrogio Professor, and Christina Curtis, PhD, professor of medicine (oncology) and of genetics, were awarded a $50,000 SCI Pancreatic Cancer Innovation Award for their proposal “Engineering of personalized medicine organoids for pancreatic ductal adenocarcinoma.”

SCI Women's Cancer Center Innovation Awards

Shmunis Family Innovation Awards in Cancer Therapeutics

  • From inhibition to activation: A novel siglec-based strategy for cancer immunotherapy

    Carolyn Bertozzi, PhD, Baker Family Director of Stanford ChEM-H, Anne T. and Robert M. Bass Professor in the School of Humanities and Sciences, was awarded a $50,000 Shmunis Family Innovation Award in Cancer Therapeutics for her project entitled “From inhibition to activation: A novel siglec-based strategy for cancer immunotherapy.”

  • Targeting hyperactive mTORC2 in lung cancer

    Kacper Rogala, PhD, assistant professor of structural biology and of chemical and systems biology, was awarded a $50,000 Shmunis Family Innovation Award in Cancer Therapeutics for his proposal titled “Targeting hyperactive mTORC2 in lung cancer.”

Behar Innovation Award in Sarcoma Research

SCI Nodal Award

SCI Innovation Awards

SCI Pancreatic Cancer Innovation Awards

  • Inserting a switch into IL-2 to develop PD-1-dependent immunotherapy

    A $50,000 Stanford Women's Cancer Center Innovation award was awarded to Danny Chou, PhD, Assistant Professor of Pediatrics and, by courtesy, of Chemical and Systems Biology, and his collaborator Everett Meyer, MD, PhD, Associate Professor of Medicine, for their project entitled “Inserting a switch into IL-2 to develop PD-1-dependent immunotherapy.”

  • Can changing cancer mindsets improve biomarkers of immune functioning?

    A $50,000 Stanford Women's Cancer Center Innovation award was awarded to Alia Crum, PhD, Associate Professor of Psychology and, by courtesy, of Medicine; Lidia Schapira, MD, Professor of Medicine (Oncology); Michael Snyder, PhD, Stanford W. Ascherman Professor of Genetics; and David Spiegel, MD, PhD, Jack, Lulu, and Sam Willson Professor of Medicine, Psychiatry and Behavioral Sciences, for their project entitled “Can changing cancer mindsets improve biomarkers of immune functioning? Piloting the effects of a novel digital intervention on direct-to-patient blood sampling and multiomics profiling.”

  • Feasibility of community based same day cervical cancer screening for refuge women in Tijuana, Mexico

    A $50,000 Stanford Women's Cancer Center Innovation award was awarded to Kay Daniels, MD, Clinical Professor, Obstetrics and Gynecology, and Paul Blumenthal, MD, MPH, Professor of Obstetrics and Gynecology, for their project entitled “Feasibility of community based same day cervical cancer screening for refuge women in Tijuana, Mexico.”

  • Novel strategies to improve ovarian cancer sensitivity to immunotherapy

    Oliver Dorigo, MD, PhD, Associate Professor of Obstetrics and Gynecology (Oncology), was awarded a $50,000 Stanford Women's Cancer Center Innovation award for his project entitled “Novel strategies to improve ovarian cancer sensitivity to immunotherapy.”

  • Disparities in second primary breast cancer and inflammatory biomarkers

    A $50,000 Stanford Women's Cancer Center Innovation award was awarded to Esther John, PhD, MSPH, Professor of Epidemiology and Population Health and of Medicine, and her collaborators, Allison Kurian, MD, Professor of Medicine (Oncology) and of Epidemiology and Population Health, and Holden Maecker, PhD, Professor of Microbiology and Immunology, for their project entitled “Disparities in second primary breast cancer and inflammatory biomarkers.”

  • The impact of multiraciality, comorbidity, and geography on cancer disparities among the Native Hawaiian and Other Pacific Islander Population in the United States

    A $50,000 Stanford Women's Cancer Center Innovation award was awarded to Erqi Pollom, MD, Associate Professor of Radiation Oncology and, by courtesy, of Neurosurgery, and her collaborators Manali Patel, MD, Assistant Professor of Medicine (Oncology), and Kekoa Taparra, MD, PhD, resident physician-scientist trainee in the Department of Radiation Oncology, for their project entitled “The impact of multiraciality, comorbidity, and geography on cancer disparities among the Native Hawaiian and Other Pacific Islander Population in the United States.”

  • Volume and Symmetry Outcomes in Unilateral Omentum-based Breast Reconstruction

    A $50,000 Stanford Women's Cancer Center Innovation award was awarded to Irene Wapnir, MD, Professor of Surgery, and her collaborator Dung Nguyen, MD, Pharm. D, Clinical Professor of Plastic & Reconstructive Surgery, for their project entitled “Volume and symmetry outcomes in unilateral omentum-based breast reconstruction.”

Shmunis Family Innovation Awards in Cancer Therapeutics

  • Harnessing an E3 ligase for pancreatic cancer therapy

    Steven Corsello, MD, Assistant Professor of Medicine (Oncology), was awarded a $50,000 Shmunis Family Innovation Awards in Cancer Therapeutics award for his project entitled “Harnessing an E3 ligase for pancreatic cancer therapy.”

Behar Innovation Award in Sarcoma Research

SCI Innovation Award

SCI Cancer Innovation Award

  • “Targeting Human Breast Cancer Metastases by a Novel Therapeutic Antibody” Shoshana Levy, PhD
  • “Engineering Next-generation Breast Cancer Cell Therapies: Targeting HER2 heterogeneity” Rogelio Hernandez-Lopez, PhD
  • “Neoadjuvant Pembrolizumab Cetuximab for Locally Advanced Betel Nut Induced Oral Cavity Cancer (NEOCORAL) Phase II Clinical Trial” Quynh Le, MD
  • "In Vivo Modeling of the Tumor Mutational Load and its Effect on Tumor Suppression and Response to Therapy" Dmitri Petrov, PhD; Monte Winslow, PhD
SCI Innovation Award

Under One Umbrella - Women’s Cancer Center Innovation Award

  • "Faster is Better: Artificial Intelligence Optimized Cervical Cancer Brachytherapy Treatment Customization" Elizabeth Kidd, MD; Thomas Niedermayr, PhD
  • "Establishing a Fallopian Tube Organoid System to Investigate Potential Pathogens in Ovarian Cancer” Bo Yu, MD

SCI Innovation Award

SCI Cancer Innovation Award

  • “ALCANCE Food for Health Equity” Patel, Manali; Goldman Rosas, Lisa
  • “Community Partnerships to Improve Cancer Survivorship Care for Adolescents/Young Adults in the San Joaquin Valley” Schapira, Lidia; Smith, Stephanie
  • “Multi-Tracer PET imaging for Prostate Cancer Detection Using Context-Aware Generative Models from a single PET” Levin, Craig
  • "Median Survival to Life Expectancy: How Cancer Trial-Reported Outcomes Relate to Clinical Benefit, Population Health, and Health Equity " Goldhaber-Fiebert, Jeremy; Owens, Doug; Caswell-Jim, Jennifer
SCI Innovation Award

Stanford Women’s Cancer Center Innovation Award

  • "Leveraging image-based sequencing to dissect multicellular regulation in ovarian cancer" Jerby, Livnat; Howitt, Brooke
  • "Tumor Infiltrating Lymphocytes and Breast Cancer Mortality in Racially/Ethnically Diverse Participants of the Northern California Breast Cancer Family Registry” Telli, Melinda; John, Esther
  • “Live cell imaging of the cytoskeleton during NK and ovarian tumor cell trogocytosis” Fantl, Wendy; Jackson, Peter
  • "Modeling endometrial cancer using genetically engineered primary organoids"  Kuo, Calvin
SCI Innovation Award

SCI Nodal Grant Award

“Bioengineering antibodies with phage display to overcome T cell exhaustion in tumors” Lim, Michael; Cochran, Jennifer

SCI Innovation Award

SCI Cancer Innovation Award

  • “A Multi-tiered Genomic and Transcriptomic Predictor of Response to Immunotherapy in Sarcomas” Nam Bui, MD (Everett Moding, MD, PhD)
  • “Which Men Benefit From Prostate Cancer Screening? A Machine Learning-Enhanced Regression Discontinuity Analysis to Identify Heterogeneous Treatment Effects in Stanford's and National Cancer Patient Cohorts” Tina Hernandez-Boussard, MD, PhD
  • “A Novel Approach to Enhance the Potency and Specificity of CAR T Cells for Solid Tumors” Robbie Majzner, MD
SCI Innovation Award

SCI Pancreatic Cancer Innovation Award

  • “A Conceptually New Approach to NET-Targeted Chemotherapeutic Delivery” Justin Annes, MD, PhD
  • “Targeting Pancreatic Cancer with ALDH1B1 Antagonists” James Chen, PhD
  • “Synthetic-Circuit-Mediated Immunotherapy Against KRAS-Driven Pancreatic Cancer” Xiaojing Gao, PhD
  • “Deciphering the Impact of Neoadjuvant Chemotherapy on the Antitumor Immunity and Antibody Delivery in Pancreatic Cancer Patients Using Single-Cell Spatial Mapping” George Poultside, MD (George Fisher, MD)
SCI Innovation Award

Stanford Women’s Cancer Center Innovation Award

  • "Comprehensive Molecular Profiling of Primary Angiosarcomas and Hemangiomas of the Breast to Aide in Diagnosis and Treatment" Gregory Bean, MD, PhD
  • "Preclinical Model for Evaluating FLASH Radiotherapy for Breast Cancer” Frederick Dirbas, MD (Ted Graves, PhD; Kathleen Horst, MD; Bill Loo, MD, PhD)
  • “Differential Compartmentalization of the Actin-Binding Protein CapG Increases Breast and Ovarian Cancer Cell Invasiveness” Oliver Dorigo, MD, PhD
  • "Revealing the Potential for mSWI/SNF as Biomarkers in Breast Cancers"  Capucine Van Rechem, PhD
SCI Innovation Award

SCI Nodal Grant Award

  • “Impact of COVID-19 on Cancer-Directed Management and Outcomes.” Sumit Shah, MD, PhD
  • “Determining and Targeting Mechanisms Controlling Cancer Cell Division” Jan Skotheim, PhD (Julien Sage, PhD)

SCI Innovation Award

SCI Cancer Innovation Award

  • “Synergizing CAR-T Cell Therapy with Radiation for the Treatment of Brain Tumors.” Edward Graves, PhD
  • “Universal Sterilization of Blood Products through Next-Generation Ultra-High Dose Rate Linear Accelerator Irradiation.” Tho D. Pham, MD; Bill Loo, MD, PhD; Edward Graves, PhD; Sami Tantawi, PhD
  • “A New Mechanism for Checkpoint Inhibition.” Christopher Garcia, PhD
  • “Defining the Relationship Between Somatic Symptoms and Fear of Cancer Recurrence to Improve Health Outcomes for Young Female Cancer Survivors: A Pilot Study.” Lidia Schapira, MD
SCI Innovation Award

SCI Pancreatic Cancer Innovation Award

  • “Investigation of the Epigenetic Enzyme NSD2 as a Therapeutic Target in Pancreatic Cancer.” OrGozani, MD, PhD
  • “Development of a More Effective KRAS-Based Vaccine for the Treatment of Pancreatic Cancer.” Albert J. Wong, MD
  • “Pancreatic Cancer Treatment by Disrupting Total EGFR Signaling Through AGR2 Inhibition.” Anson Lowe, MD
  • “Evaluating Treatment Trends, Care Fragmentation and Outcomes for Pancreatic Cancer in California.” Brendan C. Visser, MD
SCI Innovation Award

Stanford Women’s Cancer Center Innovation Award

  • "Identification of Critical Drivers in High Risk of Relapse Estrogen Receptor-Positive Patient-Derived Breast Cancer Organoids Using CRISPRi/a Screens" Christina Curtis, PhD; Michael Bassik, PhD
  • "Development of a Multi-omic Liquid Biopsy Assay for the Pre-operative Diagnosis of Uterine SmoothMuscle Tumors.” Matt van de Rijn, MD, PhD
  • “Tubal Origin of High-Grade Serous Carcinoma: A Closer Look at Early Events in Pathogenesis.” Brooke Howitt, MD
SCI Innovation Award

SCI Nodal Grant Award

  • “Integrated Sensor and Omics Monitoring to Evaluate CAR-T Adverse Events.” Surbhi Sidana, MD
  • “Elucidating Autoimmunityin Patients with Thymic Epithelial Tumors.” Sukhmani Padda, MD; Kenneth Weinberg, MD; Joseph P. Shrager, MD; William Robinson, MD, PhD
  • “Expanding the Reach of the Stanford Brain Metastases Consortium: Deep Profiling of Brain Metastases through Multiplexed Analysis and Multi-PI Collaborations.” Melanie Hayden Gephart, MD

SCI Cancer Innovation Award

  • “Uncovering the oxaliplatin mechanism of action”; Onn Brandman, PhD
  • “Development and Evaluation of the Healthy Futures Module: A Community Resource for Youth Tobacco/Vaping Cessation”; Bonnie Halpern-Felsher, PhD
  • “A federated deep learning system for AI cancer evaluation”; Daniel Rubin, MD, MS
  • “Quality of life, Cognitive Functioning, Access to Care and Financial Burden in Patients Receiving Chimeric Antigen Receptor T Cell Therapy”; Surbhi Sidana, MD,  Lori Muffly, MD, MS, Llana Yurkiewicz, MD
  • “Assessment of Molecular Response and Genomic Selection During Therapy with Chimeric Antigen Receptor T-cells from Circulating Tumor DNA” ; Brian Sworder, MD, PhD, Ash Alizadeh, MD, PhD, David Kurtz, MD, PhD
SCI Innovation Award

SCI Pancreatic Cancer Innovation Award

  • “The molecular basis of metabolic rewiring in pancreatic ductal adenocarcinoma”; Monther Abu-Remaileh, PhD
  • “ZDHHC5: a New Candidate Target for Pancreatic Cancer”; Scott Dixon, PhD

Stanford Women’s Cancer Center Innovation Award

  • “Integrative Systems analysis of BRCA-mutant and BRCA-wild type HGSC tumors”; Wendy Fantl, PhD,  Brooke Howitt, MD, Andrew Gentles, PhD
  • “Addressing mental health disparities among Latina breast cancer patients”; Lisa Goldman Rosas, PhD, MPH,  Maria Juarez-Reyes, MD, PhD
  • “Anti-VISTA immunotherapy for metastatic triple-negative breast cancer”; Joshua Gruber, MD, PhD, Melinda Telli, MD
  • “Phase I dose finding and image characterization study introducing novel use of GCSF and FDG-PET to individualize bone marrow sparing radiotherapy for gynecologic cancer”; Elizabeth Kidd, MD, Dimitre Hristov, PhD
  • “Optimizing Innovative Retention Strategies for Randomized Clinical Trials of Women's Cancers” ; Michaela Kiernan, PhD
SCI Innovation Award

SCI Nodal Grant Award

“Head and Neck Cancer SPORE Application Planning Grant”; John Sunwoo, MD, MA, Quynh-Thu Le, MD