The Proteomics Shared Resource fosters high-impact cancer research by providing SCI members with access to cutting-edge, user-friendly mass spectrometry-based resources. The analytical offerings cover a broad and constantly developing range of application areas, including protein expression, stability, structure and/or function; small molecule drug discovery; metabolic pathway analysis; biologics characterization, and chemical tissue imaging. In addition to providing facilities and services, the resource offers multiple avenues for customized, hands-on user training, instructing on topics from sample preparation to methods development for bespoke new applications designed to meet the rapidly evolving needs of cancer researchers.
The resource houses 16 mass spectrometers and associated instrumentation, along with in-house data processing capabilities and expert staff to support all stages of project development.
The resource offers the following services to SCI members:
- Spatial analysis of molecules (chemical imaging) in tissues, arrays, etc.
- Peptide and protein identification
- Characterization of post-translational modifications
- Quantitative proteomic studies
- Biomarker verification, targeted metabolite studies, and panels
- Drug discovery support, biologics characterization
The resource provides both individualized and group opportunities for education and hands-on training in modern mass spectrometry techniques to the Stanford research community. Our focus is to enhance users' research via biological mass spectrometry methods. Our diverse staff provides end-to-end high-quality, on-campus mass spectrometry support so that researchers may become more involved with experimental design, data analysis, and results interpretation, developing a real understanding of these powerful results.
