Adolescents and young adults newly diagnosed with cancer report high rates of depression and anxiety in the months following diagnosis and onset of treatment. Digital phenotyping allows for the easy collection of passive and active data via smartphone applications, wearable devices, and ecological momentary assessment (EMA) of symptoms that have been reliably linked to elevated levels of distress. This study, with the support of the SCI Nodal award, will recruit N=25 adolescents and young adults recently diagnosed with cancer at the Bass Center in order to identify psychosocial at-risk profiles using cutting-edge technologies, including HeartRhythms EMA data collection system (i.e., generating insights into human behavior to predict negative outcomes before they occur) and Whoop Strap wrist-based photoplethysmography (i.e., collecting heart rate with a watch-based device).