Stem Cells

Old muscle stem cells express high levels of the cancer-associated molecule CD47. Blocking a pathway mediated by CD47 restored strength to old mice in a Stanford Medicine study.

Researchers have shown initial viability of an embryo that contains both chimpanzee and macaque cells in a preliminary study that explores the feasibility of primate organ genesis.

Muscle stem cells enter a deep resting state during fasting or when fed a high-fat ketogenic diet, a Stanford-led study finds. This promotes stem cell resilience but slows injury repair.

Stanford scientists have developed a device that delivers and electrically stimulates stem cells to promote stroke healing.

Stanford researcher Maria Grazia Roncarolo has been awarded $12 million by the California Institute for Regenerative Medicine for a trial aimed at improving the outcomes of stem cell transplants in children and young adults with blood cancers.

The California Institute for Regenerative Medicine has awarded $31 million to three Stanford researchers to launch trials of treatments for common diseases. Four other Stanford researchers also received a total of $4.55 million.

Researchers have found that old skeletal stem cells contribute to bone fragility and poor healing in mice, but that a stem cell-boosting gel may help restore function.

Researchers have identified the mechanism of scar formation in skin and demonstrated in mice a way to make wounds heal with normal skin instead of scar tissue.

A single protein is a master regulator of mouse muscle function during aging, a Stanford study finds. Blocking this protein increased muscle strength and endurance in old animals. It may play a role in age-related muscle weakening in humans.

In laboratory studies, Stanford School of Medicine researchers have found a way to regenerate the cartilage that eases movement between bones.

Researchers at the Stanford School of Medicine have discovered that cells infected by viruses or bacteria send out a “don’t eat me” signal to avoid attack by the body’s immune system.