Aging & Geriatrics
Old muscle stem cells express high levels of the cancer-associated molecule CD47. Blocking a pathway mediated by CD47 restored strength to old mice in a Stanford Medicine study.
Rare mutation protects against Alzheimer's
Researchers have discovered that a rare mutation inherited with the APOE4 gene variant protects against Alzheimer's, shedding new light on ways to counteract high-risk genes for the disease.
Anne Brunet wins Lurie Prize
Anne Brunet was awarded the 2022 Lurie Prize in Biomedical Sciences for her efforts to understand the mechanism of aging.
Transfusion boosts brain function
In a Stanford study, sedentary mice appear to benefit from another same-aged mouse’s exercise — if they receive injections of its blood.
Healthy-aging proponent James Fries dies at 83
The professor of rheumatology and immunology created an early computer database to follow rheumatology patients. The knowledge he gained from it precipitated his “compression of morbidity” hypothesis.
Schulman on value of new Alzheimer’s drug
The Food and Drug Administration has approved a new and expensive medication for Alzheimer’s disease, but it’s not clear it helps. Researcher Kevin Schulman discusses what the government should consider before deciding to cover it.
Inflammatory-aging ‘clock’ predicts health
Scientists at Stanford and the Buck Institute have found a way to predict an individual’s immunological decline as well as the likelihood of incurring age-associated diseases and becoming frail.
Study reveals immune driver of brain aging
Scientists have identified a key factor in mental aging and shown that it might be prevented or reversed by fixing a glitch in the immune system’s front-line soldiers.
Molecule restores strength in old mice
A single protein is a master regulator of mouse muscle function during aging, a Stanford study finds. Blocking this protein increased muscle strength and endurance in old animals. It may play a role in age-related muscle weakening in humans.
High-risk, high-reward grants for researchers
Annelise Barron, Peter Kim, Siddhartha Jaiswal and Keren Haroush will receive grants totaling $10 million to fund their investigations. The awards support risky efforts that could potentially have a big impact in the biomedical sciences.
How to better care for older adults at lower cost
Stanford Medicine researchers spotlight three approaches to late-life care that, if implemented broadly, could save tens of billions of dollars.
Alzheimer’s Disease Research Center grant
The Stanford-based center’s affiliated faculty and staff, aided by more than 400 volunteers, conduct research on Alzheimer’s and Parkinson’s diseases and related disorders.
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