Animal Research

Neutrophils often suppress the immune system’s response to cancer, but when activated, they eliminate several types of tumors in laboratory mice, a study led by Stanford Medicine has found.

Old muscle stem cells express high levels of the cancer-associated molecule CD47. Blocking a pathway mediated by CD47 restored strength to old mice in a Stanford Medicine study.

A technique developed at Stanford Medicine allows mice with diabetes to accept unmatched islet cells and durably restores blood sugar control without immunosuppression or graft-versus-host disease.

Lab-grown clusters of human brain cells integrate so well into young rats’ brains they enable researchers to study neurodevelopmental disorders’ molecular and circuit underpinnings.

A key developmental gene governs the number and length of spines in the stickleback, Stanford Medicine researchers find. The discovery supports the concept of progressive evolution in nature.

Researchers have shown initial viability of an embryo that contains both chimpanzee and macaque cells in a preliminary study that explores the feasibility of primate organ genesis.

Stanford Medicine researchers and their collaborators have identified a molecule that staves off hunger post-exercise.

Stanford researchers modified anti-cancer CAR-T cells so they can be controlled with an oral drug. The modified cells are safer, more potent and more active against solid tumors in mice.

Stanford scientists have developed a device that delivers and electrically stimulates stem cells to promote stroke healing.

In a Stanford study, sedentary mice appear to benefit from another same-aged mouse’s exercise — if they receive injections of its blood.

A single protein is a master regulator of mouse muscle function during aging, a Stanford study finds. Blocking this protein increased muscle strength and endurance in old animals. It may play a role in age-related muscle weakening in humans.