Uytengsu-Hamilton 22q11 Neuropsychiatry Research Awards Program

FY 2024 Awards

Laramie Duncan, PhD 
Assistant Professor, Psychiatry and Behavioral Sciences, Stanford School of Medicine
Study Title: Discovering cell type specificity of 22q11.2DS genes

Sarah Heilshorn, PhD
Professor, Materials Science and Engineering, Stanford University
Study Title: Investigating neuronal migration defects in spatially patterned assembloid models of 22q11.2 deletion syndrome

Anca Pasca, MD
Assistant Professor, Pediatrics, Stanford University
Study Title: PIONEER-22q Study: Psychedelic Interventions in Organoids to study Neuropsychiatric Efficacy and Evidence-Based Remedies for 22q11.2DS

Stewart Anderson, MD
Professor, Child and Adolescent Psychiatry, Children's Hospital of Pennsylvania
Study Title: Do hyper-sensitive microglia excessively prune synapses in people with 22q11.2 deletion syndrome and schizophrenia?

Denis Jabaudon, PhD
Professor, Developmental Neurobiology, University of Geneva
Study Title: Dissecting gene autonomous and non-autonomous effects of the 22q11 microdeletion on neurodevelopment

Maria Mascarenhas, MBBS
Professor, Pediatric Gastroenterology, University of Pennsylvania and Children's Hospital of Philadelphia
Study Title: Whole-Child Wellness: A Path to Developing Resilience for Patients and Families Affected by 22q11.2 Deletion Syndrome

FY 2023 Awards

Casey Gifford, PhD
Assistant Professor, Pediatrics, Stanford School of Medicine
Study Title: Defining the Cardiac Gene Regulatory Networks Perturbed in 22q11 Deletion Syndrome

Makoto Kawai, MD
Clinical Associate Professor, Psychiatry and Behavioral Sciences, Stanford School of Medicine
Study Title: Characterizing sleep in 22q11.2 deletion syndrome with micro EEG system

Longzhi Tan, PhD
Assistant Professor, Neurobiology, Stanford University
Study Title: Measuring Cell Type-Specific 3D Genome Architectural Aberrations in the 22q11.2DS Cerebellum with Single-Cell In Vivo Multi-Omics

Marius Wernig, MD, PhD
Professor, Pathology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University
Study Title: Molecular dissection of the 22q11.2 deletion in human neurons

Flora Tassone, PhD
Professor, Biochemistry and Molecular Medicine, MIND Institute, UC Davis
Study Title: Molecular biomarkers of psychosis-proneness in 22q11.2 deletion syndrome

Stanislav Zakharenko, PhD
Professor, Developmental Biology, St. Jude Children’s Research Hospital
Study Title: Cerebellar-thalamocortical neural circuitry dysfunction in psychiatric symptoms of 22q11.2 deletion syndrome

FY 2022 Awards

Birgitt Schuele, MD
Associate Professor, Pathology, Stanford School of Medicine 
Study Title: Deciphering Early Neurodegenerative Mechanisms in 22q11.2 Deletion Syndrome

Alexander Urban, PhD
Associate Professor, Psychiatry and Behavioral Sciences, and Genetics, Stanford School of Medicine 
Study Title: Revealing the Molecular Activity of the 22q11 Segdup Regions, Potential Modifiers of Phenotype and Hubs of Connectivity 

Jorge Alvarez, PhD 
Assistant Professor, Pathology and Veterinary Medicine, University of Pennsylvania 
Study Title: Dysregulation Within the Brain-Immune Axis in the 22q11.2 Deletion Syndrome

Alessandro Gozzi, PhD
Senior Scientist, Functional Neuroimaging, Italian Institute of Technology 
Study Title: Unravelling Developmental Connectopathy in 22q11.2 Deletion Syndrome

Ralda Nehme, PhD
Group Leader, Stanley Center for Psychiatric Genetics, Broad Institute  
Study Title: Defining Human Neuronal Phenotypes Linked to 22q11.2 Deletion

Kathleen Sullivan, MD PhD
Professor of Pediatrics, Children’s Hospital of Philadelphia  
Study Title: Immune dysfunction in 22q11.2 Deletion Syndrome Associated with Schizophrenia Spectrum Disorders

FY 2021 Awards

Mark Kay, MD PhD
Professor, Pediatrics (Human Gene Therapy) and Genetics, Stanford School of Medicine 
Study Title: Developing Novel Adeno-associated Virus Vectors for Gene Therapy of 22q11.2 Deletion Syndrome

Michael Lin, MD, PhD
Associate Professor, Neurobiology and Bioengineering, Stanford University   
Study Title: Visualizing and Reversing Electrical Abnormalities in a Mouse Model of 22q11.2 Deletion Syndrome

Anca Pasca, MD
Assistant Professor, Pediatrics (Neonatology), Stanford School of Medicine
Study Title: Identification of Metabolic Disturbances in the Developing Brain of Individuals with 22q11.2 Deletion Syndrome

Lei Stanley Qi, PhD
Associate Professor, Bioengineering and Chemical and Systems Biology, Stanford University
Study Title: Systematic Identification and Correction of Genes Defining the Neuropsychiatric Phenotype in 22q11 Deletion Syndrome Using the CRISPR Toolbox

Therese van Amelsvoort, MD, PhD
Professor, Psychiatry and Neuropsychology, Maastricht University
Study Title: The Glutamate/GABA Balance as Novel Therapeutic Target for Psychotic and Cognitive Symptoms In 22q11.2 Deletion Syndrome

Stanislav Zakharenko, MD, PhD
Professor, Developmental Neurobiology, St Jude Children’s Research Hospital
Study Title: Focal Cerebellar Abnormality in Patients and Mouse Models Of 22q11 Deletion Syndrome

FY 2020 Awards

Vinod Menon, PhD
Professor, Psychiatry & Behavioral Sciences
Study Title: Leveraging Big Data and Using Deep Learning Neural Networks to Predict Progression of Psychosis in 22q11 DS

Thomas Sudhof, MD
Professor, Molecular and Cellular Physiology
Study Title: Multi-level Analysis of Mouse and Human Neurons with the 22q11.2 Deletion

Alexander Urban, PhD 
Assistant Professor, Psychiatry & Behavioral Sciences and Genetics
Study Title: A Genome Analysis Method to Detect and Resolve the Exact Boundaries of the 22q11 Deletion