MCHRI Virtual Seminar Series
The MCHRI Virtual Seminar Series highlight compelling clinical topics, innovative research, and the latest developments in maternal and child health, and serves as a forum for engaging in conversations with other researchers and scientists across the community.
Students, faculty, and postdoctoral researchers are encouraged to attend the seminars. Seminars are typically from 12:00pm-1:00pm at the specified locations listed in the registration portal. For question about registration, please contact Neta Miller.
Upcoming 2022 Speakers
December 5, 2022
Using single cell approaches to understand neointimal lesion formation and growth in Pulmonary Hypertension
The seminar will discuss the single cell approach we are taking to understand how arteries change in pulmonary arterial hypertension (PAH), a disease characterized by profound vascular remodeling. In PAH, pulmonary arteries narrow due to medial thickening and occlusion by neointimal lesions, which leads to elevated pulmonary vascular resistance and ultimately right heart failure. Therapies targeting the neointima would represent a significant advance in PAH treatment, and by understanding of the cellular events driving neointima formation, and the molecular pathways that control them, we hope to open the door to new treatments. Using a wide array of approaches -- genetic lineage tracing, clonal analysis, single cell RNA-sequencing, bioinformatic interaction mapping, multiplexed in situ hybridization, immunostaining, deep confocal imaging and staged pharmacologic inhibition – we are defining the cell behaviors underlying each stage of vascular remodeling, the progenitor populations that operate at each stage, and identifying the pathways that control them.
Speakers:
Maya Kumar, PhD
Lea Steffes, MD
Past Seminars
January 10, 2022
Research in the Real World: Reducing Disparities in Our Backyard
Baraka Floyd, MD, MSc
Clinical Assistant Professor, Pediatrics, Associate Chair for Diversity, Equity, and Inclusion
Janine Bruce, DrPH, MPH
Co-Director of Pediatric Advocacy Program, Co-Director for the Scholarly Concentration in Community Engagement and Advocacy, Pediatric Residency Program,
Anisha Patel, MD, MSHS
Associate Professor in the Division of General Pediatrics, Equity Analytics, Office of Child Health Equity
Tom Robinson, MD, MPH
rving Schulman, MD Endowed Professor in Child Health, Director, Stanford Solutions Science Lab, Director, Center for Healthy Weight
February 7, 2022
High-throughput Neuroscience Research and 22q11 Deletion Syndrome by a Novel CRISPR Toolbox
Stanley Qi, PhD, Assistant Professor, Department of Bioengineering, Department of Chemical and Systems Biology
Michael Chavez, PhD Student in Bioengineering
March 7, 2022 at 12:00-1:00 PM PST
Designing Innovations to Improve Health and Health Care
TOPIC:
MCHRI annually sponsor Stanford Byers Center for Biodesign Faculty Fellowships to spur innovations in maternal and child health, offering faculty the opportunity to apply their knowledge to advance care delivered through Stanford Children’s Health. Over an 8-month period, Faculty Fellows learn about the process of identifying innovation opportunities, inventing cost-effective solutions, and preparing to implement those inventions to improve patient care. At this talk, learn about the education and training opportunities offered through Biodesign, hear from current Faculty Fellows present rapid pitches of their projects, and receive updates from past alumni on their ongoing work designed to address health technology challenges and needs.
March 21, 2022 at 12:00-1:00 PM PST
Immune-Epithelial Interaction in Pediatric IBD:
Is Type 2 good for you?
TOPIC:
Join this IBD focused seminar featuring Dr. Michael Rosen and Dr. Babajide Ojo. Discussion will include ongoing research to molecularly and functionally characterize patient-derived colon organoids as a human in vitro model of pediatric ulcerative colitis. Also learn how a mucosal type 2 immune response associated with outcome in pediatric ulcerative colitis and the effect of type 2 cytokines on intestinal epithelial
SPEAKERS:
Michael J. Rosen, MD, MSCI, Stanford University Endowed Professor for Pediatric IBD & Celiac Disease
Babajide Ojo, PhD, Postdoctoral Fellow, Rosen Laboratory
April 4, 2022 at 12:00-1:00 PM PST
Artificial Intelligence in Medicine and Imaging: Examples from Maternal and Child Health
Curt Langlotz, MD, PhD, Professor of Radiology and Biomedical Informatics: The Center for AI in Medicine and Imaging
Heike Daldrup-Link, MD, PhD, Professor of Radiology and Pediatrics (by courtesy): Using Machine Learning to Analyze PET/MRI of Pediatric Patients
Alison Callahan, PhD, Research Scientist, Center for Biomedical Informatics: Making PROGRESS: Constructing an obstetric research database using EHRs and text mining
April 7, 2022 at 8:00-9:00 AM PST
22q11 Deletion Syndrome Seminar: Spotlight on Immunology
The Stanford 22q11 Deletion Syndrome Seminar aimed to encourage close interdisciplinary dialogue through a series of quarterly research seminars throughout 2022.
Spotlight on Immunology Seminar Speakers:
Dr. Kathleen Sullivan, CHOP
Dr. John Sleasman, Duke University
Dr. Andrew Gennery, Newcastle University
Moderator: Dr. Katja Weinacht, Stanford University
May 2, 2022 at 12:00-1:00 PM PST
Spatial mapping of the human maternal fetal interface: a normative template for vascular remodeling and immune tolerance
Little is known about the regulation of the maternal immune response to the fetus. We aim to use this MIBI to delineate immune cell populations and their spatial organization in order to reveal the pathways that lead to spiral artery remodeling and induction of the regulatory immune response to the fetus. In addition to addressing a basic question in reproductive biology - why does the maternal immune system not attack the fetus - this research also aims to address obstetric complications related to immunological responses such as preeclampsia and preterm birth.
Speakers & Topics:
Michael Angelo, MD, PhD, Assistant Professor of Pathology
High dimensional imaging platform and imaging human decidua in the first 20 weeks of pregnancy
Ke Leow, Graduate student
Recent data on maternal fetal glycosylation
June 20, 2022 at 12:00-1:00 PM PST
Insights into metabolic tissue development and function from human genetics
Join this MCHRI seminar to learn how the Translational Genomics of Diabetes Lab uses insights from large genomic discovery efforts for type 2 diabetes to understand defects in metabolic tissues and shed light on pathways for therapeutic development.
Speakers:
Anna Gloyn, DPhil, Professor of Pediatrics (Endocrinology) and, by courtesy, of Genetics
Nicole Krentz, PhD, Postdoctoral Scholar, Endocrinology and Metabolism
September 12, 2022
Seminal Issues in Asian Health and Collaborative Opportunities
Join this MCHRI seminar to learn how the Center for Asian Health Research and Education supports Stanford SOM researchers interested in MFM and pediatric research. This seminar will review critical issues in Asian health, and several projects supported by our CARE Scholars research program
November 7, 2022
Leveraging PEDSnet
PEDSnet is a multi-site network that utilizes a common data model to enable a Pediatric Learning Health System that leverages a common governance structure, administrative efficiencies, and logistical, scientific and training resources. Gain insight on how to leverage this powerful tool for your research.
Speakers:
Grace Lee, MD, MPH, PEDSnet Site Principal Investigator, Professor, Pediatrics (Infectious Diseases)
Keith Morse, MD, MBA, PEDSnet Co-Site Principal Investigator/Informatics Lead, Clinical Assistant Professor, Pediatrics
Yair Bannett, MD, Instructor, Pediatrics
