Clinical Trials Unit
Stanford University School of Medicine's Center for Advanced Dermatologic Investigation is the Dermatology Department's clinical trials unit.
The Center is home to 12-15 ongoing clinical studies, investigating the safety and efficacy of new and currently available drugs and over-the-counter medications. The Center works with Stanford's own panel on medical research, leading pharmaceutical companies,and the Food and Drug Administration to safely and ethically expand the medical field's knowledge of dermatologic treatments. New studies begin regularly, and the Center continues to recruit patients with skin aging, sun damage, skin cancer (including basal cell carcinomas), psoriasis, atopic dermatitis, rosacea, and other dermatologic diseases for ongoing studies.
Skin Aging Studies
We seek to understand the human aging processes as it relates to skin on a fundamental level. To this end, our studies focus on clinical and translational research efforts ranging from: (1) the analysis of gene changes which predispose individuals to exceptionally youthful skin to (2) molecular signatures that may be biomarkers for aging skin to (3) the careful study of new candidate agents which might affect the skin aging process.
Nonmelanoma Skin Cancer
Recent advances in our understanding of basal cell skin cancer biology have enabled the development of cutting edge study drugs which combat tumor growth. We are currently home to a number of clinical trials at the forefront of potential therapy for advanced or metastatic basal cell cancer. In addition, we seek to understand the biology of basal cell skin cancers and to identify molecular predictors for treatment success.
Acne Rosecea
This is a common and frustrating chronic inflammatory condition of the face, usually affecting older individuals. The causes of this complex condition are the subject of much study. Our clinical studies seek to identify new topical or oral medications to improve the symptoms of acne rosacea.
Contact
For more information, please email dermtrials@stanford.edu
Featured Clinical Trials
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
This trial examines colorectal cancer incidence in participants with 1 to 2 non-advanced adenomas randomized to surveillance colonoscopy at 10 years compared to participants randomized to surveillance colonoscopy at 5 and 10 years.
Stanford is currently accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- procedure: 5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy
Eligibility
Inclusion Criteria:
- • The participant must have signed and dated an IRB-approved consent form that
conforms to federal and institutional guidelines.
- Participants with a first-time diagnosis of 1-2 non-advanced tubular adenomas
(less than 10 mm without tubulovillous or villous changes or high grade or severe
dysplasia) from the qualifying colonoscopy within 4 years prior to randomization.
- Sessile serrated polyps/adenomas, as long as they do not meet the criteria for
advanced adenomas, will be considered as non-advanced adenomas.
- Qualifying colonoscopy must be a complete colonoscopy with visualization of the
cecum and with adequate cleansing within 4 years prior to randomization.
- Complete excision of all observed polyps in qualifying colonoscopy
- Participants must be able to read or understand English or Spanish.
Exclusion Criteria:
- • Prior history of colorectal cancer or colorectal adenomas including sessile serrated
polyps/adenomas excluding those found on the qualifying colonoscopy.
- Prior history of a hyperplastic polyp measuring greater than or equal to 1 cm in
size.
- Traditional serrated adenomas found on the qualifying colonoscopy.
- Hyperplastic polyp measuring greater than or equal to 1 cm in size found on the
qualifying colonoscopy.
- Previous malignancies unless the patient has been disease-free for 5 or more
years prior to randomization and is deemed by the physician to be at low risk for
recurrence. Patients with the following cancers are eligible if diagnosed and
treated within the past 5 years: all in situ cancers and basal cell and squamous
cell carcinoma of the skin.
- Colonoscopy performed after the qualifying colonoscopy but prior to
randomization.
- Incomplete qualifying colonoscopy (e.g., cecum not visualized).
- Incomplete endoscopic excision of adenomatous polyps based on colonoscopist
impression at qualifying colonoscopy. (Excision of all hyperplastic rectosigmoid
polyps is not required.)
- Sub-total colectomy or total proctocolectomy. (Segmental resections are allowed.)
- Family history of CRC diagnosed at greater than or equal to 60 years of age in a
first degree relative (mother, father, child, sibling) or in two first degree
relatives with CRC at any age.
- Participants with a clinical diagnosis of a significant heritable risk for
colorectal cancer (Familial Adenomatous Polyposis, Hereditary Nonpolyposis
Colorectal Cancer [Lynch Syndrome]).
- Participants tested positive for a Familial Adenomatous Polyposis, Hereditary
Nonpolyposis Colorectal Cancer [Lynch Syndrome] genetic mutation that increases
risk of colorectal cancer.
- Inflammatory bowel disease (e.g., Crohn's Disease, ulcerative colitis).
- Life expectancy less than 10 years due to comorbid conditions in the opinion of
the investigator.
- Other comorbid conditions that would prevent the participant from having
colonoscopies or would prevent required follow-up.
Ages Eligible for Study
50 Years - 70 Years
Genders Eligible for Study
All
Now accepting new patients
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Michelle Narayan
650-725-2732
I'm interested
Psoriasis Clinical Trials
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
This trial examines colorectal cancer incidence in participants with 1 to 2 non-advanced adenomas randomized to surveillance colonoscopy at 10 years compared to participants randomized to surveillance colonoscopy at 5 and 10 years.
Stanford is currently accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- procedure: 5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy
Eligibility
Inclusion Criteria:
- • The participant must have signed and dated an IRB-approved consent form that
conforms to federal and institutional guidelines.
- Participants with a first-time diagnosis of 1-2 non-advanced tubular adenomas
(less than 10 mm without tubulovillous or villous changes or high grade or severe
dysplasia) from the qualifying colonoscopy within 4 years prior to randomization.
- Sessile serrated polyps/adenomas, as long as they do not meet the criteria for
advanced adenomas, will be considered as non-advanced adenomas.
- Qualifying colonoscopy must be a complete colonoscopy with visualization of the
cecum and with adequate cleansing within 4 years prior to randomization.
- Complete excision of all observed polyps in qualifying colonoscopy
- Participants must be able to read or understand English or Spanish.
Exclusion Criteria:
- • Prior history of colorectal cancer or colorectal adenomas including sessile serrated
polyps/adenomas excluding those found on the qualifying colonoscopy.
- Prior history of a hyperplastic polyp measuring greater than or equal to 1 cm in
size.
- Traditional serrated adenomas found on the qualifying colonoscopy.
- Hyperplastic polyp measuring greater than or equal to 1 cm in size found on the
qualifying colonoscopy.
- Previous malignancies unless the patient has been disease-free for 5 or more
years prior to randomization and is deemed by the physician to be at low risk for
recurrence. Patients with the following cancers are eligible if diagnosed and
treated within the past 5 years: all in situ cancers and basal cell and squamous
cell carcinoma of the skin.
- Colonoscopy performed after the qualifying colonoscopy but prior to
randomization.
- Incomplete qualifying colonoscopy (e.g., cecum not visualized).
- Incomplete endoscopic excision of adenomatous polyps based on colonoscopist
impression at qualifying colonoscopy. (Excision of all hyperplastic rectosigmoid
polyps is not required.)
- Sub-total colectomy or total proctocolectomy. (Segmental resections are allowed.)
- Family history of CRC diagnosed at greater than or equal to 60 years of age in a
first degree relative (mother, father, child, sibling) or in two first degree
relatives with CRC at any age.
- Participants with a clinical diagnosis of a significant heritable risk for
colorectal cancer (Familial Adenomatous Polyposis, Hereditary Nonpolyposis
Colorectal Cancer [Lynch Syndrome]).
- Participants tested positive for a Familial Adenomatous Polyposis, Hereditary
Nonpolyposis Colorectal Cancer [Lynch Syndrome] genetic mutation that increases
risk of colorectal cancer.
- Inflammatory bowel disease (e.g., Crohn's Disease, ulcerative colitis).
- Life expectancy less than 10 years due to comorbid conditions in the opinion of
the investigator.
- Other comorbid conditions that would prevent the participant from having
colonoscopies or would prevent required follow-up.
Ages Eligible for Study
50 Years - 70 Years
Genders Eligible for Study
All
Now accepting new patients
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Michelle Narayan
650-725-2732
I'm interested
Dermatology Clinical Trials
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
This trial examines colorectal cancer incidence in participants with 1 to 2 non-advanced adenomas randomized to surveillance colonoscopy at 10 years compared to participants randomized to surveillance colonoscopy at 5 and 10 years.
Stanford is currently accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- procedure: 5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy
Eligibility
Inclusion Criteria:
- • The participant must have signed and dated an IRB-approved consent form that
conforms to federal and institutional guidelines.
- Participants with a first-time diagnosis of 1-2 non-advanced tubular adenomas
(less than 10 mm without tubulovillous or villous changes or high grade or severe
dysplasia) from the qualifying colonoscopy within 4 years prior to randomization.
- Sessile serrated polyps/adenomas, as long as they do not meet the criteria for
advanced adenomas, will be considered as non-advanced adenomas.
- Qualifying colonoscopy must be a complete colonoscopy with visualization of the
cecum and with adequate cleansing within 4 years prior to randomization.
- Complete excision of all observed polyps in qualifying colonoscopy
- Participants must be able to read or understand English or Spanish.
Exclusion Criteria:
- • Prior history of colorectal cancer or colorectal adenomas including sessile serrated
polyps/adenomas excluding those found on the qualifying colonoscopy.
- Prior history of a hyperplastic polyp measuring greater than or equal to 1 cm in
size.
- Traditional serrated adenomas found on the qualifying colonoscopy.
- Hyperplastic polyp measuring greater than or equal to 1 cm in size found on the
qualifying colonoscopy.
- Previous malignancies unless the patient has been disease-free for 5 or more
years prior to randomization and is deemed by the physician to be at low risk for
recurrence. Patients with the following cancers are eligible if diagnosed and
treated within the past 5 years: all in situ cancers and basal cell and squamous
cell carcinoma of the skin.
- Colonoscopy performed after the qualifying colonoscopy but prior to
randomization.
- Incomplete qualifying colonoscopy (e.g., cecum not visualized).
- Incomplete endoscopic excision of adenomatous polyps based on colonoscopist
impression at qualifying colonoscopy. (Excision of all hyperplastic rectosigmoid
polyps is not required.)
- Sub-total colectomy or total proctocolectomy. (Segmental resections are allowed.)
- Family history of CRC diagnosed at greater than or equal to 60 years of age in a
first degree relative (mother, father, child, sibling) or in two first degree
relatives with CRC at any age.
- Participants with a clinical diagnosis of a significant heritable risk for
colorectal cancer (Familial Adenomatous Polyposis, Hereditary Nonpolyposis
Colorectal Cancer [Lynch Syndrome]).
- Participants tested positive for a Familial Adenomatous Polyposis, Hereditary
Nonpolyposis Colorectal Cancer [Lynch Syndrome] genetic mutation that increases
risk of colorectal cancer.
- Inflammatory bowel disease (e.g., Crohn's Disease, ulcerative colitis).
- Life expectancy less than 10 years due to comorbid conditions in the opinion of
the investigator.
- Other comorbid conditions that would prevent the participant from having
colonoscopies or would prevent required follow-up.
Ages Eligible for Study
50 Years - 70 Years
Genders Eligible for Study
All
Now accepting new patients
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Michelle Narayan
650-725-2732
I'm interested
Pediatric Dermatology Clinical Trials
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
This trial examines colorectal cancer incidence in participants with 1 to 2 non-advanced adenomas randomized to surveillance colonoscopy at 10 years compared to participants randomized to surveillance colonoscopy at 5 and 10 years.
Stanford is currently accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- procedure: 5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy
Eligibility
Inclusion Criteria:
- • The participant must have signed and dated an IRB-approved consent form that
conforms to federal and institutional guidelines.
- Participants with a first-time diagnosis of 1-2 non-advanced tubular adenomas
(less than 10 mm without tubulovillous or villous changes or high grade or severe
dysplasia) from the qualifying colonoscopy within 4 years prior to randomization.
- Sessile serrated polyps/adenomas, as long as they do not meet the criteria for
advanced adenomas, will be considered as non-advanced adenomas.
- Qualifying colonoscopy must be a complete colonoscopy with visualization of the
cecum and with adequate cleansing within 4 years prior to randomization.
- Complete excision of all observed polyps in qualifying colonoscopy
- Participants must be able to read or understand English or Spanish.
Exclusion Criteria:
- • Prior history of colorectal cancer or colorectal adenomas including sessile serrated
polyps/adenomas excluding those found on the qualifying colonoscopy.
- Prior history of a hyperplastic polyp measuring greater than or equal to 1 cm in
size.
- Traditional serrated adenomas found on the qualifying colonoscopy.
- Hyperplastic polyp measuring greater than or equal to 1 cm in size found on the
qualifying colonoscopy.
- Previous malignancies unless the patient has been disease-free for 5 or more
years prior to randomization and is deemed by the physician to be at low risk for
recurrence. Patients with the following cancers are eligible if diagnosed and
treated within the past 5 years: all in situ cancers and basal cell and squamous
cell carcinoma of the skin.
- Colonoscopy performed after the qualifying colonoscopy but prior to
randomization.
- Incomplete qualifying colonoscopy (e.g., cecum not visualized).
- Incomplete endoscopic excision of adenomatous polyps based on colonoscopist
impression at qualifying colonoscopy. (Excision of all hyperplastic rectosigmoid
polyps is not required.)
- Sub-total colectomy or total proctocolectomy. (Segmental resections are allowed.)
- Family history of CRC diagnosed at greater than or equal to 60 years of age in a
first degree relative (mother, father, child, sibling) or in two first degree
relatives with CRC at any age.
- Participants with a clinical diagnosis of a significant heritable risk for
colorectal cancer (Familial Adenomatous Polyposis, Hereditary Nonpolyposis
Colorectal Cancer [Lynch Syndrome]).
- Participants tested positive for a Familial Adenomatous Polyposis, Hereditary
Nonpolyposis Colorectal Cancer [Lynch Syndrome] genetic mutation that increases
risk of colorectal cancer.
- Inflammatory bowel disease (e.g., Crohn's Disease, ulcerative colitis).
- Life expectancy less than 10 years due to comorbid conditions in the opinion of
the investigator.
- Other comorbid conditions that would prevent the participant from having
colonoscopies or would prevent required follow-up.
Ages Eligible for Study
50 Years - 70 Years
Genders Eligible for Study
All
Now accepting new patients
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Michelle Narayan
650-725-2732
I'm interested
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
This trial examines colorectal cancer incidence in participants with 1 to 2 non-advanced adenomas randomized to surveillance colonoscopy at 10 years compared to participants randomized to surveillance colonoscopy at 5 and 10 years.
Stanford is currently accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- procedure: 5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy
Eligibility
Inclusion Criteria:
- • The participant must have signed and dated an IRB-approved consent form that
conforms to federal and institutional guidelines.
- Participants with a first-time diagnosis of 1-2 non-advanced tubular adenomas
(less than 10 mm without tubulovillous or villous changes or high grade or severe
dysplasia) from the qualifying colonoscopy within 4 years prior to randomization.
- Sessile serrated polyps/adenomas, as long as they do not meet the criteria for
advanced adenomas, will be considered as non-advanced adenomas.
- Qualifying colonoscopy must be a complete colonoscopy with visualization of the
cecum and with adequate cleansing within 4 years prior to randomization.
- Complete excision of all observed polyps in qualifying colonoscopy
- Participants must be able to read or understand English or Spanish.
Exclusion Criteria:
- • Prior history of colorectal cancer or colorectal adenomas including sessile serrated
polyps/adenomas excluding those found on the qualifying colonoscopy.
- Prior history of a hyperplastic polyp measuring greater than or equal to 1 cm in
size.
- Traditional serrated adenomas found on the qualifying colonoscopy.
- Hyperplastic polyp measuring greater than or equal to 1 cm in size found on the
qualifying colonoscopy.
- Previous malignancies unless the patient has been disease-free for 5 or more
years prior to randomization and is deemed by the physician to be at low risk for
recurrence. Patients with the following cancers are eligible if diagnosed and
treated within the past 5 years: all in situ cancers and basal cell and squamous
cell carcinoma of the skin.
- Colonoscopy performed after the qualifying colonoscopy but prior to
randomization.
- Incomplete qualifying colonoscopy (e.g., cecum not visualized).
- Incomplete endoscopic excision of adenomatous polyps based on colonoscopist
impression at qualifying colonoscopy. (Excision of all hyperplastic rectosigmoid
polyps is not required.)
- Sub-total colectomy or total proctocolectomy. (Segmental resections are allowed.)
- Family history of CRC diagnosed at greater than or equal to 60 years of age in a
first degree relative (mother, father, child, sibling) or in two first degree
relatives with CRC at any age.
- Participants with a clinical diagnosis of a significant heritable risk for
colorectal cancer (Familial Adenomatous Polyposis, Hereditary Nonpolyposis
Colorectal Cancer [Lynch Syndrome]).
- Participants tested positive for a Familial Adenomatous Polyposis, Hereditary
Nonpolyposis Colorectal Cancer [Lynch Syndrome] genetic mutation that increases
risk of colorectal cancer.
- Inflammatory bowel disease (e.g., Crohn's Disease, ulcerative colitis).
- Life expectancy less than 10 years due to comorbid conditions in the opinion of
the investigator.
- Other comorbid conditions that would prevent the participant from having
colonoscopies or would prevent required follow-up.
Ages Eligible for Study
50 Years - 70 Years
Genders Eligible for Study
All
Now accepting new patients
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Michelle Narayan
650-725-2732
I'm interested
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
This trial examines colorectal cancer incidence in participants with 1 to 2 non-advanced adenomas randomized to surveillance colonoscopy at 10 years compared to participants randomized to surveillance colonoscopy at 5 and 10 years.
Stanford is currently accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- procedure: 5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy
Eligibility
Inclusion Criteria:
- • The participant must have signed and dated an IRB-approved consent form that
conforms to federal and institutional guidelines.
- Participants with a first-time diagnosis of 1-2 non-advanced tubular adenomas
(less than 10 mm without tubulovillous or villous changes or high grade or severe
dysplasia) from the qualifying colonoscopy within 4 years prior to randomization.
- Sessile serrated polyps/adenomas, as long as they do not meet the criteria for
advanced adenomas, will be considered as non-advanced adenomas.
- Qualifying colonoscopy must be a complete colonoscopy with visualization of the
cecum and with adequate cleansing within 4 years prior to randomization.
- Complete excision of all observed polyps in qualifying colonoscopy
- Participants must be able to read or understand English or Spanish.
Exclusion Criteria:
- • Prior history of colorectal cancer or colorectal adenomas including sessile serrated
polyps/adenomas excluding those found on the qualifying colonoscopy.
- Prior history of a hyperplastic polyp measuring greater than or equal to 1 cm in
size.
- Traditional serrated adenomas found on the qualifying colonoscopy.
- Hyperplastic polyp measuring greater than or equal to 1 cm in size found on the
qualifying colonoscopy.
- Previous malignancies unless the patient has been disease-free for 5 or more
years prior to randomization and is deemed by the physician to be at low risk for
recurrence. Patients with the following cancers are eligible if diagnosed and
treated within the past 5 years: all in situ cancers and basal cell and squamous
cell carcinoma of the skin.
- Colonoscopy performed after the qualifying colonoscopy but prior to
randomization.
- Incomplete qualifying colonoscopy (e.g., cecum not visualized).
- Incomplete endoscopic excision of adenomatous polyps based on colonoscopist
impression at qualifying colonoscopy. (Excision of all hyperplastic rectosigmoid
polyps is not required.)
- Sub-total colectomy or total proctocolectomy. (Segmental resections are allowed.)
- Family history of CRC diagnosed at greater than or equal to 60 years of age in a
first degree relative (mother, father, child, sibling) or in two first degree
relatives with CRC at any age.
- Participants with a clinical diagnosis of a significant heritable risk for
colorectal cancer (Familial Adenomatous Polyposis, Hereditary Nonpolyposis
Colorectal Cancer [Lynch Syndrome]).
- Participants tested positive for a Familial Adenomatous Polyposis, Hereditary
Nonpolyposis Colorectal Cancer [Lynch Syndrome] genetic mutation that increases
risk of colorectal cancer.
- Inflammatory bowel disease (e.g., Crohn's Disease, ulcerative colitis).
- Life expectancy less than 10 years due to comorbid conditions in the opinion of
the investigator.
- Other comorbid conditions that would prevent the participant from having
colonoscopies or would prevent required follow-up.
Ages Eligible for Study
50 Years - 70 Years
Genders Eligible for Study
All
Now accepting new patients
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Michelle Narayan
650-725-2732
I'm interested