Clinical Trials Unit
Stanford University School of Medicine's Center for Advanced Dermatologic Investigation is the Dermatology Department's clinical trials unit.
The Center is home to 12-15 ongoing clinical studies, investigating the safety and efficacy of new and currently available drugs and over-the-counter medications. The Center works with Stanford's own panel on medical research, leading pharmaceutical companies,and the Food and Drug Administration to safely and ethically expand the medical field's knowledge of dermatologic treatments. New studies begin regularly, and the Center continues to recruit patients with skin aging, sun damage, skin cancer (including basal cell carcinomas), psoriasis, atopic dermatitis, rosacea, and other dermatologic diseases for ongoing studies.
Skin Aging Studies
We seek to understand the human aging processes as it relates to skin on a fundamental level. To this end, our studies focus on clinical and translational research efforts ranging from: (1) the analysis of gene changes which predispose individuals to exceptionally youthful skin to (2) molecular signatures that may be biomarkers for aging skin to (3) the careful study of new candidate agents which might affect the skin aging process.
Nonmelanoma Skin Cancer
Recent advances in our understanding of basal cell skin cancer biology have enabled the development of cutting edge study drugs which combat tumor growth. We are currently home to a number of clinical trials at the forefront of potential therapy for advanced or metastatic basal cell cancer. In addition, we seek to understand the biology of basal cell skin cancers and to identify molecular predictors for treatment success.
Acne Rosecea
This is a common and frustrating chronic inflammatory condition of the face, usually affecting older individuals. The causes of this complex condition are the subject of much study. Our clinical studies seek to identify new topical or oral medications to improve the symptoms of acne rosacea.
Contact
For more information, please email dermtrials@stanford.edu
Featured Clinical Trials
Electrical Stimulation for Continence After Spinal Cord Injury
This study aims to improve continence and voiding of patients with spinal cord injury using electrical stimulation.
The Finetech Vocare Bladder System is an implantable sacral nerve stimulator for improving bladder and bowel function in patients with spinal cord injury (SCI). It has been commercially available in Britain and other countries since 1982, and has been used in thousands of patients with SCI to improve bladder, bowel and sexual function. It received FDA approval in 1998 under Humanitarian Device Exemption H980005 and H980008 for providing urination on demand and to aid in bowel evacuation.
Electrical stimulation to produce bladder contraction and improve bladder voiding after spinal cord injury has usually been combined with cutting of sensory nerves to reduce reflex contraction of the bladder, which improves continence. However, cutting these nerves has undesirable side effects. This study will not cut any sensory nerve. This study is testing the use of the stimulator for inhibiting bladder contraction by stimulating sensory nerves to improve continence after spinal cord injury, and for blocking sphincter contraction to improve voiding.
Stanford is currently accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- device: Finetech Vocare Bladder System
Eligibility
Inclusion Criteria:
Subjects will be included if they meet all of the following criteria:
- Complete spinal cord injury (AIS grade A) of at least 2 years duration with
neurological level (ISNCSCI level) below C4
- Impaired bladder emptying due to Detrusor External Sphincter Dyssynergia-DESD
(unco-ordinated contraction of bladder and external urethral sphincter) as shown on
video-urodynamic testing.
- Impaired continence due to detrusor hyper-reflexia
Exclusion Criteria:
Subjects will be excluded if they meet any of the following criteria:
- Absence of reflex contractions of the bladder as shown on urodynamic testing
- Absence of reflex contractions of the external urethral sphincter as shown on
urodynamic testing with EMG
- External sphincterotomy, urethral stricture or previous urethral or sphincter or
bladder or prostate surgery
- History of pelvic fracture
- Subjects on anticoagulants or with coagulation disorders
- Immunosuppressed subjects
- Active or recurrent pressure ulcers, particularly in sacral, ischial or trochanteric
areas
- Active untreated infection
- Active implanted medical device such as cardiac pacemaker or defibrillator
- Progressive spinal cord injury
- Pregnancy
- Mechanical ventilator dependency
- Any other significant co-morbidity or illness that would preclude their participation
or increase the risk to them of participating in the study
- Inability or unwillingness to follow study protocol or give informed consent
Ages Eligible for Study
22 Years - N/A
Genders Eligible for Study
All
Now accepting new patients
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
SPECTRUM
6507042394
I'm interested
Psoriasis Clinical Trials
Electrical Stimulation for Continence After Spinal Cord Injury
This study aims to improve continence and voiding of patients with spinal cord injury using electrical stimulation.
The Finetech Vocare Bladder System is an implantable sacral nerve stimulator for improving bladder and bowel function in patients with spinal cord injury (SCI). It has been commercially available in Britain and other countries since 1982, and has been used in thousands of patients with SCI to improve bladder, bowel and sexual function. It received FDA approval in 1998 under Humanitarian Device Exemption H980005 and H980008 for providing urination on demand and to aid in bowel evacuation.
Electrical stimulation to produce bladder contraction and improve bladder voiding after spinal cord injury has usually been combined with cutting of sensory nerves to reduce reflex contraction of the bladder, which improves continence. However, cutting these nerves has undesirable side effects. This study will not cut any sensory nerve. This study is testing the use of the stimulator for inhibiting bladder contraction by stimulating sensory nerves to improve continence after spinal cord injury, and for blocking sphincter contraction to improve voiding.
Stanford is currently accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- device: Finetech Vocare Bladder System
Eligibility
Inclusion Criteria:
Subjects will be included if they meet all of the following criteria:
- Complete spinal cord injury (AIS grade A) of at least 2 years duration with
neurological level (ISNCSCI level) below C4
- Impaired bladder emptying due to Detrusor External Sphincter Dyssynergia-DESD
(unco-ordinated contraction of bladder and external urethral sphincter) as shown on
video-urodynamic testing.
- Impaired continence due to detrusor hyper-reflexia
Exclusion Criteria:
Subjects will be excluded if they meet any of the following criteria:
- Absence of reflex contractions of the bladder as shown on urodynamic testing
- Absence of reflex contractions of the external urethral sphincter as shown on
urodynamic testing with EMG
- External sphincterotomy, urethral stricture or previous urethral or sphincter or
bladder or prostate surgery
- History of pelvic fracture
- Subjects on anticoagulants or with coagulation disorders
- Immunosuppressed subjects
- Active or recurrent pressure ulcers, particularly in sacral, ischial or trochanteric
areas
- Active untreated infection
- Active implanted medical device such as cardiac pacemaker or defibrillator
- Progressive spinal cord injury
- Pregnancy
- Mechanical ventilator dependency
- Any other significant co-morbidity or illness that would preclude their participation
or increase the risk to them of participating in the study
- Inability or unwillingness to follow study protocol or give informed consent
Ages Eligible for Study
22 Years - N/A
Genders Eligible for Study
All
Now accepting new patients
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
SPECTRUM
6507042394
I'm interested
Dermatology Clinical Trials
Electrical Stimulation for Continence After Spinal Cord Injury
This study aims to improve continence and voiding of patients with spinal cord injury using electrical stimulation.
The Finetech Vocare Bladder System is an implantable sacral nerve stimulator for improving bladder and bowel function in patients with spinal cord injury (SCI). It has been commercially available in Britain and other countries since 1982, and has been used in thousands of patients with SCI to improve bladder, bowel and sexual function. It received FDA approval in 1998 under Humanitarian Device Exemption H980005 and H980008 for providing urination on demand and to aid in bowel evacuation.
Electrical stimulation to produce bladder contraction and improve bladder voiding after spinal cord injury has usually been combined with cutting of sensory nerves to reduce reflex contraction of the bladder, which improves continence. However, cutting these nerves has undesirable side effects. This study will not cut any sensory nerve. This study is testing the use of the stimulator for inhibiting bladder contraction by stimulating sensory nerves to improve continence after spinal cord injury, and for blocking sphincter contraction to improve voiding.
Stanford is currently accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- device: Finetech Vocare Bladder System
Eligibility
Inclusion Criteria:
Subjects will be included if they meet all of the following criteria:
- Complete spinal cord injury (AIS grade A) of at least 2 years duration with
neurological level (ISNCSCI level) below C4
- Impaired bladder emptying due to Detrusor External Sphincter Dyssynergia-DESD
(unco-ordinated contraction of bladder and external urethral sphincter) as shown on
video-urodynamic testing.
- Impaired continence due to detrusor hyper-reflexia
Exclusion Criteria:
Subjects will be excluded if they meet any of the following criteria:
- Absence of reflex contractions of the bladder as shown on urodynamic testing
- Absence of reflex contractions of the external urethral sphincter as shown on
urodynamic testing with EMG
- External sphincterotomy, urethral stricture or previous urethral or sphincter or
bladder or prostate surgery
- History of pelvic fracture
- Subjects on anticoagulants or with coagulation disorders
- Immunosuppressed subjects
- Active or recurrent pressure ulcers, particularly in sacral, ischial or trochanteric
areas
- Active untreated infection
- Active implanted medical device such as cardiac pacemaker or defibrillator
- Progressive spinal cord injury
- Pregnancy
- Mechanical ventilator dependency
- Any other significant co-morbidity or illness that would preclude their participation
or increase the risk to them of participating in the study
- Inability or unwillingness to follow study protocol or give informed consent
Ages Eligible for Study
22 Years - N/A
Genders Eligible for Study
All
Now accepting new patients
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
SPECTRUM
6507042394
I'm interested
Pediatric Dermatology Clinical Trials
Electrical Stimulation for Continence After Spinal Cord Injury
This study aims to improve continence and voiding of patients with spinal cord injury using electrical stimulation.
The Finetech Vocare Bladder System is an implantable sacral nerve stimulator for improving bladder and bowel function in patients with spinal cord injury (SCI). It has been commercially available in Britain and other countries since 1982, and has been used in thousands of patients with SCI to improve bladder, bowel and sexual function. It received FDA approval in 1998 under Humanitarian Device Exemption H980005 and H980008 for providing urination on demand and to aid in bowel evacuation.
Electrical stimulation to produce bladder contraction and improve bladder voiding after spinal cord injury has usually been combined with cutting of sensory nerves to reduce reflex contraction of the bladder, which improves continence. However, cutting these nerves has undesirable side effects. This study will not cut any sensory nerve. This study is testing the use of the stimulator for inhibiting bladder contraction by stimulating sensory nerves to improve continence after spinal cord injury, and for blocking sphincter contraction to improve voiding.
Stanford is currently accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- device: Finetech Vocare Bladder System
Eligibility
Inclusion Criteria:
Subjects will be included if they meet all of the following criteria:
- Complete spinal cord injury (AIS grade A) of at least 2 years duration with
neurological level (ISNCSCI level) below C4
- Impaired bladder emptying due to Detrusor External Sphincter Dyssynergia-DESD
(unco-ordinated contraction of bladder and external urethral sphincter) as shown on
video-urodynamic testing.
- Impaired continence due to detrusor hyper-reflexia
Exclusion Criteria:
Subjects will be excluded if they meet any of the following criteria:
- Absence of reflex contractions of the bladder as shown on urodynamic testing
- Absence of reflex contractions of the external urethral sphincter as shown on
urodynamic testing with EMG
- External sphincterotomy, urethral stricture or previous urethral or sphincter or
bladder or prostate surgery
- History of pelvic fracture
- Subjects on anticoagulants or with coagulation disorders
- Immunosuppressed subjects
- Active or recurrent pressure ulcers, particularly in sacral, ischial or trochanteric
areas
- Active untreated infection
- Active implanted medical device such as cardiac pacemaker or defibrillator
- Progressive spinal cord injury
- Pregnancy
- Mechanical ventilator dependency
- Any other significant co-morbidity or illness that would preclude their participation
or increase the risk to them of participating in the study
- Inability or unwillingness to follow study protocol or give informed consent
Ages Eligible for Study
22 Years - N/A
Genders Eligible for Study
All
Now accepting new patients
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
SPECTRUM
6507042394
I'm interested
Electrical Stimulation for Continence After Spinal Cord Injury
This study aims to improve continence and voiding of patients with spinal cord injury using electrical stimulation.
The Finetech Vocare Bladder System is an implantable sacral nerve stimulator for improving bladder and bowel function in patients with spinal cord injury (SCI). It has been commercially available in Britain and other countries since 1982, and has been used in thousands of patients with SCI to improve bladder, bowel and sexual function. It received FDA approval in 1998 under Humanitarian Device Exemption H980005 and H980008 for providing urination on demand and to aid in bowel evacuation.
Electrical stimulation to produce bladder contraction and improve bladder voiding after spinal cord injury has usually been combined with cutting of sensory nerves to reduce reflex contraction of the bladder, which improves continence. However, cutting these nerves has undesirable side effects. This study will not cut any sensory nerve. This study is testing the use of the stimulator for inhibiting bladder contraction by stimulating sensory nerves to improve continence after spinal cord injury, and for blocking sphincter contraction to improve voiding.
Stanford is currently accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- device: Finetech Vocare Bladder System
Eligibility
Inclusion Criteria:
Subjects will be included if they meet all of the following criteria:
- Complete spinal cord injury (AIS grade A) of at least 2 years duration with
neurological level (ISNCSCI level) below C4
- Impaired bladder emptying due to Detrusor External Sphincter Dyssynergia-DESD
(unco-ordinated contraction of bladder and external urethral sphincter) as shown on
video-urodynamic testing.
- Impaired continence due to detrusor hyper-reflexia
Exclusion Criteria:
Subjects will be excluded if they meet any of the following criteria:
- Absence of reflex contractions of the bladder as shown on urodynamic testing
- Absence of reflex contractions of the external urethral sphincter as shown on
urodynamic testing with EMG
- External sphincterotomy, urethral stricture or previous urethral or sphincter or
bladder or prostate surgery
- History of pelvic fracture
- Subjects on anticoagulants or with coagulation disorders
- Immunosuppressed subjects
- Active or recurrent pressure ulcers, particularly in sacral, ischial or trochanteric
areas
- Active untreated infection
- Active implanted medical device such as cardiac pacemaker or defibrillator
- Progressive spinal cord injury
- Pregnancy
- Mechanical ventilator dependency
- Any other significant co-morbidity or illness that would preclude their participation
or increase the risk to them of participating in the study
- Inability or unwillingness to follow study protocol or give informed consent
Ages Eligible for Study
22 Years - N/A
Genders Eligible for Study
All
Now accepting new patients
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
SPECTRUM
6507042394
I'm interested
Electrical Stimulation for Continence After Spinal Cord Injury
This study aims to improve continence and voiding of patients with spinal cord injury using electrical stimulation.
The Finetech Vocare Bladder System is an implantable sacral nerve stimulator for improving bladder and bowel function in patients with spinal cord injury (SCI). It has been commercially available in Britain and other countries since 1982, and has been used in thousands of patients with SCI to improve bladder, bowel and sexual function. It received FDA approval in 1998 under Humanitarian Device Exemption H980005 and H980008 for providing urination on demand and to aid in bowel evacuation.
Electrical stimulation to produce bladder contraction and improve bladder voiding after spinal cord injury has usually been combined with cutting of sensory nerves to reduce reflex contraction of the bladder, which improves continence. However, cutting these nerves has undesirable side effects. This study will not cut any sensory nerve. This study is testing the use of the stimulator for inhibiting bladder contraction by stimulating sensory nerves to improve continence after spinal cord injury, and for blocking sphincter contraction to improve voiding.
Stanford is currently accepting patients for this trial.
Stanford Investigator(s):
Intervention(s):
- device: Finetech Vocare Bladder System
Eligibility
Inclusion Criteria:
Subjects will be included if they meet all of the following criteria:
- Complete spinal cord injury (AIS grade A) of at least 2 years duration with
neurological level (ISNCSCI level) below C4
- Impaired bladder emptying due to Detrusor External Sphincter Dyssynergia-DESD
(unco-ordinated contraction of bladder and external urethral sphincter) as shown on
video-urodynamic testing.
- Impaired continence due to detrusor hyper-reflexia
Exclusion Criteria:
Subjects will be excluded if they meet any of the following criteria:
- Absence of reflex contractions of the bladder as shown on urodynamic testing
- Absence of reflex contractions of the external urethral sphincter as shown on
urodynamic testing with EMG
- External sphincterotomy, urethral stricture or previous urethral or sphincter or
bladder or prostate surgery
- History of pelvic fracture
- Subjects on anticoagulants or with coagulation disorders
- Immunosuppressed subjects
- Active or recurrent pressure ulcers, particularly in sacral, ischial or trochanteric
areas
- Active untreated infection
- Active implanted medical device such as cardiac pacemaker or defibrillator
- Progressive spinal cord injury
- Pregnancy
- Mechanical ventilator dependency
- Any other significant co-morbidity or illness that would preclude their participation
or increase the risk to them of participating in the study
- Inability or unwillingness to follow study protocol or give informed consent
Ages Eligible for Study
22 Years - N/A
Genders Eligible for Study
All
Now accepting new patients
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
SPECTRUM
6507042394
I'm interested