Search Results

Stanford researchers found that manipulating the gut microbe Clostridium sporogenes changed levels of molecules in the bloodstreams of mice and, in turn, affected their health.

The Stanford research suggests that any conclusions about stem cell function based on studies of stem cells in lab dishes may now need to be reconsidered in light of the fact that the cells’ biology changes during isolation.

High-grade gliomas, a group of aggressive brain tumors, cease growing in mice if a signaling molecule called neuroligin-3 is absent or its activity is blocked with drugs, a Stanford team has shown.

“Humanized” mice are used to study human immune responses, but they are inadequate for stem cell studies, say Stanford researchers. Optimized models are needed for clinical decision-making.

The new Stanford Center for Definitive and Curative Medicine will work to turn discoveries into stem cell and gene therapies to aid the millions of people who have genetic diseases.

Ribosomes, which make proteins, are startlingly variable in their composition and associations. This variability confers on them the ability to regulate genes, confounding previous ideas, Stanford researchers say.

Stanford researchers have found that a metabolite stimulates mouse muscle stem cells to proliferate after injury, and anti-inflammatory drugs, frequently taken after exercise, block its production and inhibit muscle repair.

Targeting backup biological pathways often used by cancers can lead to more efficient drug development and less-toxic therapies. Stanford researchers have developed a new way to identify these pathways.

An antibody to the cell receptor PD-1 may launch a two-pronged assault on cancer by initiating attacks by both T cells and macrophages, a Stanford study has found.

Stanford investigators fused two stem-cell-derived neural spheroids, each containing a different type of human neuron, then watched as one set of neurons migrated and hooked up with the other set.