Blau Lab Movies and Photos
Photos
Movies
Helen Blau's interview on 90 seconds with Lisa Kim
A small molecule previously shown to enhance strength in injured or old laboratory mice does so by restoring lost connections between nerves and muscle fibers, Stanford Medicine researchers have found. The molecule blocks the activity of an aging-associated enzyme, or gerozyme, called 15-PGDH that naturally increases in muscles as they age. Read the full story here.
Inhibiting the Gerozyme 15-PGDH Rejuvenates Aged Muscle by The Blau Lab
Blau’s lab recently made the striking discovery that aged muscle stem cells and tissues can be rejuvenated and muscle strength increased by targeting a single enzyme, 15-PGDH, the Prostaglandin E2 degrading enzyme (Palla et al., Science 2021). 15-PGDH is a gerozyme, a pivotal molecular determinant of aging. These findings hold promise for translation to the clinic to augment strength in patients with heritable neuromuscular dystrophies, disuse atrophy, and sarcopenia.
Muscle Regeneration on The Stem Cell Podcast
In episode 254 of the Stem Cell Podcast, we chat with Dr. Helen Blau, the Donald E. and Delia B. Baxter Foundation Professor and Director of the Baxter Laboratory for Stem Cell Biology at Stanford University. Dr. Blau’s research focuses on the basic molecular mechanisms of stem cells and muscle and their applications in aging, regenerative medicine, and disease. Her lab aims to understand and apply biology to improve quality of life, and their current primary focus is on understanding the gerozyme 15-PGDH. She talks about the roles of NSAIDs and CD47 in muscle regeneration. She also discusses growing cultured meat and writing a children’s book!
New Life for Old Muscles on The Future of Everything
Helen Blau is a stem cell biologist and expert in why, as we age, our muscles weaken, even if we get exercise and try to stay fit. In an age when humans are living longer, our muscles are critical to living life to the fullest and Blau is helping them keep pace by recruiting stem cells to regenerate youthful muscle in older people. Join us on this episode of Stanford Engineering’s The Future of Everything podcast as Blau and host Russ Altman discuss the science of muscle regeneration.
Regenerating and Rejuvenating Aged Tissues by Targeting a Gerozyme NIH Wednesday Afternoon Lecture Series
Description: NIH Director’s Wednesday Afternoon Lecture [WALS] See https://en.wikipedia.org/wiki/Helen_Blau For more information go to https://oir.nih.gov/wals Author: Helen Blau, Ph.D., Stanford Medicine Permanent link: https://videocast.nih.gov/watch=46058
Plenary I at the 2023 ISSCR Meeting in Boston, MA
Helen Blau's lecture at the 2023 ISSCR Meeting in Boston, MA
Public Forum - Alliance for Regenerative Medicine
FEATURED PRESENTATION: REJUVENATING STEM CELL FUNCTION AND MUSCLE STRENGTH: NO PAIN, NO GAIN!
Featured Speaker: Helen M. Blau, Ph.D., Donald E. and Delia B. Baxter Foundation Professor; Director, Baxter Laboratory for Stem Cell Biology, Stanford University
Reversing Injury with Regenerative Medicine Wu Tsai Human Performance Alliance Research Symposium
Helen M. Blau, PhD, is the Donald E. and Delia B. Baxter Foundation Professor and Director of the Baxter Laboratory for Stem Cell Biology at Stanford University, and is world-renowned for her work on nuclear reprogramming and the demonstration of the plasticity of cell fate using cell fusion. In her presentation, she shares work from her lab on returning the strength of aged and weakened muscles back to a healthy, young baseline in mice.
Helen Blau (Stanford) on "Stem Cells" at a Stanford L.A.S.E.R.
The LASERs are a national program of evening gatherings that bring artists and scientists together for informal presentations and conversation with an audience. See the program for the whole series. The event is free and open to everybody. Email me if you want to be added to the mailing list for the LASERs. Like previous evenings, the agenda includes some presentations of art/science projects, news from the audience, and time for casual socializing/networking.
A Novel Treatment Strategy for VIDD from CIRM
This video is about Helen Blau of Stanford University explaining how a CIRM grant is helping her try and develop a treatment for people who have lost muscle function as a result of being on a ventilator due to COVID-19
Duchenne Muscular Dystrophy and Stem Cell Research - Helen Blau, Stanford Medicine for CIRM
In this video Dr. Helen Blau, a CIRM grantee from Stanford University, reports that her lab has generated a new mouse model that more accurately mimics the Duchenne symptoms observed in humans. This breakthrough opens up opportunities to better understand the disease and to develop novel therapies.
Pioneers in Science from Stanford University
When Carla Shatz, PhD, professor of neurobiology, and Helen Blau, PhD, professor of microbiology and immunology, came to Stanford in 1978, they were two of the first women to be hired on the tenure tract for basic science faculty. Over the decades, as their professional and personal paths have diverged and converged, they have remained the closest of friends. In this video, they discuss the courses their paths have taken and reflect on the rewards and challenges of their lives as women scientists.
Plenary Session of the Pontifical Academy of Sciences on "Basic science for human development, peace, and planetary health"
While keeping human development, peace and planetary health problems in perspective, the 2022 Biannual Plenary of the Pontifical Academy of Sciences aims to explore and highlight the driving forces and opportunities relating to basic science for human development, peace and planetary health. We will be addressing the following questions:
- What are new and emerging breakthroughs in sciences?
- How did science breakthroughs come about? And then ask
- How can they influence new, better and more effective ways to reduce the threats and problems for people, peace, and planet?
Plenary Session of Transformative Roles of Science in Society: From Emerging Basic Science toward Solutions for People's Wellbeing
Transformative Roles of Science in Society: From Emerging Basic Science toward Solutions for People's Wellbeing PLENARY SESSION OF THE PONTIFICAL ACADEMY OF SCIENCES Casina Pio IV, 12-14 November 2018.
The 2018 PAS plenary is guided by the ideas that basic sciences remain fundamental for generating a valid and evidence based model of the world sciences become ever more interconnected across disciplines, including the humanities scientists and science policy makers need to engage with society to maintain (foster) trust in science and to counter the spread of statements that are not based on scientific insights (fake news).