Clinical Trials

1.) 2011-2013  Phase 1 Rindopepimut after Conventional Radiation in Children with Diffuse Intrinsic Pontine Gliomas.  Sub-Investigator

2.) 2011-2014  Phase 3 Study of Rindopepimut in Patients with Newly Diagnosed Glioblastoma (ACT IV). Sub-Investigator

3.) 2012-2015 A Phase II Study of Rindopepimut/GM-CSF in Patients with Relapsed EGFRvIII-Positive Glioblastoma. Principal Investigator

4.) 2013-present Comparison of Overall Survival Post-CyberKnife Radiosurgery Treatment of Patients with 1-3 Versus 4 or More Brain Metastases.  Co-Investigator

5.) 2013-present  MISTIE III A Phase III, Randomized, Open-Label, 500-Subject Clinical Trial of Minimally Invasive Surgery plus rt-PA in the Treatment of Intracerebral Hemorrhage.  Sub-Investigator

6.) 2015 A Phase 2 Randomized Trial Comparing the Efficacy of Heat Shock Protein-Peptide Complex-96 (HSPPC-96) Vaccine Given with Bevacizumab versus Bevacizumab Alone in the Treatment of Surgically Resectable Recurrent Glioblastoma Multiforme. Co-Principal Investigator

7.) 2015 A Phase I Study of Ad-RTS-hIL-12, an Inducible Adenoviral Vector Engineered to Express hIL-12 in the Presence of the Activator Ligand Veledimex in Subjects with Recurrent or Progressive Glioblastoma or Grade III Malignant Glioma. Co-Principal Investigator