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A single protein is a master regulator of mouse muscle function during aging, a Stanford study finds. Blocking this protein increased muscle strength and endurance in old animals. It may play a role in age-related muscle weakening in humans.

A Stanford study shows that in severely ill COVID-19 patients, “first-responder” immune cells, which should react immediately to signs of viruses or bacteria in the body, instead respond sluggishly.

Hongjie Dai, Julie Parsonnet and Joseph Wu are among the 90 regular members and 10 international members elected this year to the academy, which aims to provide independent, scientifically informed analysis and recommendations on health issues.

The Stanford Microbiome Therapies Initiative is backed by gifts from Marc and Lynne Benioff and Mark and Debra Leslie and is focused on developing and testing new disease therapies.

Stanford researchers have found intrusive immune cells in a place in the brains of humans and older mice where new nerve cells are born. The intruders appear to impair nerve cell generation.

Immune markers and pollutant levels in the blood indicate wildfire smoke may be more harmful to children’s health than smoke from a controlled burn, Stanford researchers found.

An antibody to a protein on blood-forming stem cells may allow bone marrow transplants without the need for chemotherapy and radiation, according to a Stanford study.

The California Institute for Regenerative Medicine awarded Stanford researcher Crystal Mackall a grant to study immune cells genetically modified to attack two proteins on leukemia and lymphoma cells.

In mice, a fatal brainstem tumor was cleared by injecting it with engineered T cells that recognized the cancer and targeted it for destruction. The Stanford discovery is moving to human trials.

In a clinical trial, participants were given an antibody to CD117, a cell surface marker, in an effort to wipe out their defective blood stem cells without high-risk chemotherapy or radiation.