Search Results
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Tracking cancer evolution in the blood
Monitoring cancer DNA in blood can predict recurrence and prognosis and drive treatment decisions. A Stanford study of 92 lymphoma patients suggests similar techniques may work for other tumors.
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Paving the way for gene therapy
Using the CRISPR gene-editing technique in stem cells, Stanford researchers repaired the gene that causes sickle cell disease, and the mended stem cells were successfully transplanted into mice.
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iPS cell-derived heart cells predict drug toxicity
Heart muscle cells made from induced pluripotent stem cells share gene expression patterns with native donor tissue, researchers discovered. These cells can be used to indicate people who should avoid certain medications that could damage their hearts.
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Antibodies could counter atherosclerosis
A biological drug could be used to combat cardiovascular disease by targeting not mere risk factors such as high cholesterol or high blood pressure, but the actual lesions bearing direct responsibility: atherosclerotic plaques.
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How age affects pancreatic function
A Stanford-led national collaboration to procure and analyze human pancreatic tissue from deceased donors illustrates how the organ’s function changes as we age, and could point the way toward new diabetes treatments.
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IPS cells aid study of chemotherapy side effect
Doxorubicin is a chemotherapy drug used to treat many cancers, but it causes serious heart damage in some patients. Heart muscle cells made from the skin cells of breast cancer patients can be used to study this phenomenon.
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Improved tracking of blood-borne cancer DNA
People with cancer have tumor DNA in their blood. A new way to quiet background “noise” in the blood sample allows researchers to sequence minute quantities of these molecules to improve diagnosis and treatment.
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Discovery links cancer-promoting pathways
Researchers have identified a link between the expression of a cancer-related gene and cell-surface molecules that protect tumors from the immune system.
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Cell protein may show who needs chemo
A small subset of colon cancers lacks the CDX2 protein — a hallmark of colon tissue maturation. Patients with these cancers may benefit more than others from chemotherapy.