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The researchers also identified a molecular pathway involved in turning back the clock on the cells. Drugs that could manipulate the pathway might be an effective substitute for exercise, they suggest.

A drug may help children with Pelizaeus-Merzbacher disease, a deadly neurological disorder, according to a study by researchers at Stanford, UCSF and Cambridge.

Stanford researchers blocked a molecule to help restore neurons in rats in which the flow of fresh blood to the brain was reduced. The approach could lead to new treatments for people who have suffered a stroke or cardiac arrest.

Stanford researchers have found intrusive immune cells in a place in the brains of humans and older mice where new nerve cells are born. The intruders appear to impair nerve cell generation.

Low oxygen levels during brain development may cause particular cells to differentiate too soon, a Stanford-led study found.

Studying human oligodendrocytes, which provide insulation for nerve cells, has been challenging. But a new way of generating stem-cell-derived, three-dimensional brain-cell cultures is paying off.

Three types of cells in the brain’s white matter show interwoven problems during the cognitive dysfunction that follows treatment with the cancer drug methotrexate, Stanford neuroscientists have found.

In mice, a fatal brainstem tumor was cleared by injecting it with engineered T cells that recognized the cancer and targeted it for destruction. The Stanford discovery is moving to human trials.

Young, resting neural stem cells have large protein clumps often associated with neurodegeneration. As stem cells age, the aggregates inhibit their ability to make new neurons, Stanford researchers say.

Stanford researchers have found that a small set of nerve cells in the brain regulates the debilitating seizures and cognitive deficits characteristic of the most common form of epilepsy in adults. This discovery could lead to new and better treatments.