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Patents & Technology Transfer

  1. Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats.
    Stoughton, M, Kapur, R, Cohen, BA, Shoemaker, D, Davis RW. (2020). USA patent publication US10591391B2. [USPTO]

  2. Rare Cell Analysis Using Sample Splitting and DNA Tags.
    Shoemaker, D, Toner, M, Kapur, R, Stoughton, RB, Davis RW. (2018). USA patent publication US20150232936 [USPTO]

  3. Charge perturbation detection system for DNA and other molecules.
    Pourmand, N. Karhanek, M. Davis, RW. (2018). USA patent publication US20180346971A1 [USPTO]

  4. Sorting biological and non-biological moieties using magnetic levitation.
    Baday, M, Durmus, NG, Calamak, S, Demirci, U, Davis, RW, Steinmetz, L, Yang, J, Chinnasamy, T, Tocchio, A. (2018). USA patent publication US20180280977A1. [USPTO]

  5. Autonomous sweat extraction and analysis using a fully-integrated wearable platform.
    Emaminejad, S, Milla, C, Gao, W, Javey, A, Wu, E, Davis, RW. (2018). USA patent publication US20180070870 [USPTO]

  6. Haplotying of HLA loci with ultra-deep shotgun sequencing.
    Wang, C, Mindrinos, MN, Davis, MM, Davis, RW, Krishnakumar, S. (2018). USA patent 9,920,370 [USPTO]

  7. Wearable sensor arrays for in-situ body fluid analysis.
    Javey, A, Gao, W, Davis, RW, Emaminejad, S. (2018). USA patent publication US2016053988 [USPTO]

  8. Highly specific circular proximity ligation assay.
    Persson, HH, Jalili, R, Horecka, JL, Davis, RW. (2018). USA patent publication WO2018160397A1 [USPTO]

  9. Apparatuses and methods for determining analyte charge.
    Paik, K, Persson, HHJ, Lau, BTC, Dutton, RW, Liu, Y, Davis, RW. (2018). USA patent publication US20170097332 [USPTO]

  10. Dna-conjugated antibodies for improved antibody affinity and reduced antibody cross reactivity.
    Davis, RW, Hurlburt, N, Zahn, JM, Javanmard, M, Mok, JA. (2016). USA patent publication US20160146804 [USPTO]

  11. Re-usable analyte detector and methods.
    Harris, JS, Davis, RW, Esfandyarpour, R. (2016). USA patent publication US20160320373 [USPTO]

  12. Scalable method for isolation and sequence-verification of oligonucleotides from complex libraries.
    St Ong, RP, Schlecht, U, Levy, SF, Davis, RW, Horecka, J. (2016). USA patent publication US20160122748 [USPTO]

  13. System and method for cell levitation and monitoring.
    Demirci, U, Ghiran, I, Tasoglu, S, Davis, RW, Steinmetz, L, Durmus NG, Tekin, HC. (2016). US patent 20160370386. [USPTO]

  14. Apparatus for magnetic separation of cells.
    Davis, RW, Jeffrey, SS, Mindrinos, MN, Pease, RF, Powell, AA, Talasaz, AH. (2016). USA patent 9,267,943. [USPTO]

  15. Charge perturbation detection system for DNA and other molecules.
    Pourmand, N, Karhanek, M, Davis, RW. (2016). USA patent 9,228,971. [USPTO]

  16. Software haplotying of hla loci.
    Wang, C, Mindrinos, MN, Davis, MM, Davis, RW, Krishnakumar, S, Konstantinos, B, Fernandez-Vina, MA. (2015). WIPO patent publication WO20156200701. [USPTO]

  17. Rare cell analysis using sample splitting and DNA tags.
    Shoemaker, D, Kapur, R, Toner, M, Stoughton, R, Davis, RW. (2015). USA patent 20150232936. [USPTO]

  18. Method to produce single stranded DNA of defined length and sequence and DNA probes produced thereby.
    Mindrinos, M, Krishnakumar, S, Davis, RW, Shen, P, Scharfe, C. (2014). USA patent 8,795,968. [USPTO]

  19. Charge perturbation detection method for DNA and other molecules.
    Pourmand, N, Karhanek, M, Davis, RW. (2014). USA patent 8,753,812. [USPTO]

  20. Determination of fetal aneuploidy by quantification of genomic dna from mixed samples.
    Stoughton, R, Kapur, R, Mehmet, T, Shoemaker, D, Davis, RW. (2013). USA patent  US20130288242. [USPTO]

  21. Array-based bioactivated nanospore devices.
    Ronaghi, M, Talasaz, A, Davis, RW. (2013). USA patent 8,592,225. [USPTO]

  22. Microfluidic devices for measurement or detection involving cells or biomolecules.
    Davis, RW, Javanmard, M, Mindrinos, M, Mok, J. (2013). USA patent 8,614,056. [USPTO]

  23. Precircle probe nucleic acid amplification methods (previously: Direct Multiplex Characterization of Genomic DNA).
    Willis, T, Hardenbol, P, Jain, M, Stolc, V, Ronaghi, M, Davis, RW, (2013).  USA patent 8,383,348. [USPTO]

  24. Methods and compositions for use in analyte detection using proximity probes.
    Fredriksson, S, Davis RW,  (2013). USA patent 8,580,504. 2013. [USPTO]

  25. Fetal cell analysis using sample splitting.
    Shoemaker D, Kapur R, Toner M, Stoughton R, Davis RW. (2012). US Patent 8,168,389. [USPTO]

  26. Charge perturbation detection system for DNA and other molecules.
    Pourmand N, Karhanek M, Davis RW. (2012). US Patent 8,313,907 [USPTO]

  27. Methods for the diagnosis of fetal abnormalities.
    Kapur, R., Toner, M., Stoughton, R., Shoemaker, D., Davis, RW. (2012). US Patent 8,137,912 [USPTO]

  28. Methods and apparatus for magnetic separation of cells.
    Davis, RW., Jeffrey, SS., Mindrinos, MN., Pease, RF., Powell, AA., Hajhossein,Talasaz, A. (2011). US Patent 8,071,395 [USPTO]

  29. Precircle probe nucleic acid amplification methods.
    Willis, TD. Hardenbol, P. Jain, M. Stolc, V. Ronaghi, M. Davis, RW . (2011). US Patent 7,993,880 [USPTO]

  30. Charge perturbation detection system for DNA and other molecules.
    Pourmand, N. Karhanek, M. Davis, RW. (2011). US Patent 8,012,75 [USPTO]

  31. Rapid, informative diagnostic assay for influenza viruses including H5N1.
    Pourmand, N., Diamond, L., Kumm, J., Davis, RW. (2011). US Patent 7,989,185 [USPTO]

  32. Heat and pH measurement for sequencing of DNA.
    Esfandyarpour, H. Ronaghi, M. (2011). US Patent 7,932,034. [USPTO]

  33. Methods and compositions for use in analyte detection using proximity probes.
    Fredriksson, S., Davis, RW. (2011). US Patent 7,914,987. [USPTO]

  34. Method to produce single stranded DNA of defined length and sequence and DNA probes produced thereby.
    Mindrinos, M., Krishnakumar, S., Davis, RW. (2011). US Patent 7,897,747. [USPTO]

  35. Multiplexed assay and probes for identification of HPV types.
    Pourmand, N., Gharizadeh, B., Davis, RW. (2011). US Patent 7,875,428. [USPTO]

  36. Charge perturbation detection system for DNA and other molecules.
    Pourmand, N., Davis, RW., Karhanek, M. (2010). US Patent 7,785,785. [USPTO]

  37. Semiconductor sensor circuit arrangement.
    Ronaghi, M., Agah, A. (2010). US Patent 7,782,237. [USPTO]

  38. Devices and methods to form a randomly ordered array of magnetic beads and uses thereof.
    Jain, M., White, RL., Roberts, LA. (2010). US Patent 7,682,837. [USPTO]

  39. Method for detecting and amplifying target DNA.
    Willis, TD., Hardenbol, P., Jain, M., Stolc, V., Davis, RW. (2010). US Patent 7,700,323. [USPTO]

  40. Apparatus and methods for parallel processing of micro-volume liquid reactions.
    O'Keefe, M., Foreman, PK. (2010). US Patent 7,833,719. [USPTO]

  41. Methods and compositions for clonal amplification of nucleic acid.
    Ronaghi, M., Mashayekhi, F. (2009). US Patent 7,622,281. [USPTO]

  42. Magnetic sifter.
    Wang, SX., Pourmand, N., White, RL. (2009). US Patent 7,615,382. [USPTO]

  43. Apparatus and methods for parallel processing of micro-volume liquid reactions.
    O'Keefe, M., Foreman, PK. (2009). US Patent 7,604,983. [USPTO]

  44. Renaturation, reassociation, association and hybridization of nucleic acid molecules.
    Namsaraev, E., Davis, RW., Karlin-Neumann, G. (2009). US Patent 7,482,125. [USPTO]

  45. DNA fingerprinting using a branch migration assay.
    Pourmand, N., Davis, RW., Wang, SX. (2009). US Patent 7,501,253. [USPTO]

  46. Apparatus and methods for parallel processing of micro-volume liquid reactions.
    O'Keefe, M., Foreman, PK. (2008). US Patent 7,332,271. [USPTO]

  47. DNA fingerprinting using a branch migration assay.
    Pourmand, N., Davis, RW., Wang, SX. (2007). US Patent 7,238,486. [USPTO]

  48. Charge Sequencing: A New Technique for DNA Sequencing and SNP Detection (Transient electrical signal based methods and devices for characterizing molecular interaction and/or motion in a sample).
    Pourmand, N. Hassibi, A. (2007). US Patent 7,223,540. [USPTO]

  49. Mismatch repair detection.
    Cox, DR, Faham, M., Baharloo, S. (2006). US Patent 7,153,652. [USPTO]

  50. Renaturation, reassociation, association and hybridization of nucleic acid molecules.
    Namsaraev, E., Davis,R.W., Karlin-Neumann, G. (2006). US Patent 7,129,044. [USPTO]

  51. Bioluminescence regenerative cycle (BRC) for nucleic acid quantification.
    Pourmand, N. Hassibi, A. (2006). US Patent 7,141,370. [USPTO]

  52. Direct multiplex characterization of genomic DNA.
    Willis, T.D., Hardenbol, P., Jain, M., Stolc, V., Ronaghi, M., Davis, R.W. (2005). United States Patent 6,858,412. [USPTO]

  53. Method for determining genetic affiliation, substructure and gene flow within human populations.
    Oefner, P.J., Underhill, P.A. (2005). U.S. Patent 6,929,911. [USPTO]

  54. Dimeric fluorescent polypeptides.
    Davis, R.W. Vaillancourt, P. (2005). US Patent US Patent 6,936,428. [USPTO]

  55. Mismatch repair detection.
    Cox D., Faham, M. Bharloo, S. (2004). US Patent 6,709,827. [USPTO]

  56. Identification of drugs and drug targets by detection of the stress response.
    Davis, R.W., Giaever, G. (2004). United States Patent 6,743,583. [USPTO]

  57. Polypeptides from Chlamydia pneumoniae and their use in the diagnosis, prevention and treatment of disease.
    Stephens, R.S., Mitchell, W., Kalman, S.S., Davis, R.W. (2004). US Patent 6,822,071. [USPTO]

  58. Detection of polymorphisms by denaturing high-performance liquid chromatography.
    Oefner, P.J. (2002). United States Patent 6,453,244. [USPTO]

  59. Selecting tag nucleic acids.
    Morris, M.S., Shoemaker, D.D., Davis, R.W. Mittmann, M.P. (2002). US Patent 6,458,530. [USPTO]

  60. Recombinant mycobacteria.
    Bloom, B.R., Davis, R.W., Jacobs, Jr., R., Young, R.A., Husson, R.N. (2002). US Patent 6,372,478. [USPTO]

  61. Mismatch repair detection.
    Cox, D., Faham, M., Bahrloo, S. (2001). US Patent 6,406,847. [USPTO]

  62. Method for simultaneous centrifugation of samples.
    Marziali, A., (2001). United States Patent 6,273,848. [USPTO]

  63. Microcentrifuge.
    Marziali A., (2001), United States Patent 6,238,330. [USPTO]

  64. Recombinant mycobacterial vaccine.
    Bloom, B.R., Davis, R.W. Jacobs, Jr., W.R. Young, R.A. Husson, R.N. (2001). US Patent 6,270,776. [USPTO]

  65. Highly parallel and sensitive method for identifying drugs and drug targets.
    Davis, R.W., Giaever, G.N., Shoemaker D., (2000). United States Patent 6,046,002. [USPTO]

  66. Thermocycling apparatus and method.
    Hunicke-Smith S.P., (2000). United States Patent 6,132,996. [USPTO]

  67. Thermocycling apparatus and method.
    Hunicke-Smith S.P., (1999). United States Patent 5,985,651. [USPTO]

  68. Mycobacteriophages and uses thereof.
    Bloom, B.R., Davis; R.W., Jacobs, Jr., W.R., Young, R.A., Husson, R.N. (1999). US Patent 5,968,733. [USPTO]

  69. Cleaved amplified RFLP detection methods.
    Ausubel, F., Davis, R.W., Preuss, D. (1999). US Patent, 6,004,783. [USPTO]

  70. Apparatus and method for shear breakage of polynucleotides.
    Oefner, P.J., Hunicke-Smith S.P. (1998). United States Patent 5,846,832. [USPTO]

  71. Detection of nucleic acid heteroduplex molecules by denaturing high-performance liquid chromatography and methods for comparative sequencing.
    Oefner, P.J., Underhill, P.A., (1998). US Patent 5,795,976. Licensed to Transgenomic Inc., Omaha, NE, USA, Hewlett-Packard, Palo Alto, CA, USA, Qiagen Inc., Bothell, WA, USA, and Varian, Walnut Creek, CA, USA. [USPTO]

  72. Recombinant mycobacteria.
    Bloom, B.R. Jacobs, Jr., W.R. Davis, R.W. Young, R.A. Husson, R.N. (1998). US Patent 5,854,055. [USPTO]

  73. Software to determine optimum temperature for DHPLC given DNA sequence.
    Hansen, N.F., Oefner, P.J. (1997). Stanford University Invention Disclosure S97-175 (Tangible Research Property in conjunction with U.S. Patent 5,795,976).

  74. Nucleic Acid Separation on Alkylated Nonporous Polymer Beads. US Patent 5,585,236. (Licensed to Transgenomic Inc., Omaha, NE, USA).
    Bonn, G., Huber, C., Oefner, P.J. (1996). [USPTO]

  75. Recombinant mycobacterial vaccine.
    Bloom, BR., Davis, RW., Jacobs, Jr., WR., Young, RA., Husson, RN. (1996). US Patent 5,504,005. [USPTO]

  76. Electrophoresis using contour-clamped electric fields.
    Chu, G., Vollrath, D., Davis, R., (1996). US Patent 5,549,796. [USPTO]

  77. Method for detecting a nucleotide at a specific location within a nucleic acid using exonuclease activity.
    Davis, R.W., Myles, A. (1995). US Patent 5,391,480. [USPTO]

  78. Electrophoresis using contour-clamped electric fields.
    Chu, G., Vollrath, D., Davis, RW. (1992). US Patent 5,165,898. [USPTO]

  79. Use of the GAL1 yeast promoter.
    Botstein, D., Davis, RW., Fink, GR., Taunton-Rigby, A., Knowlton, RG., Mao, J., Moir, DT., Goff, CG. (1992). US Patent 5,139,936. [USPTO]

  80. Encoding antigens of M. Leprae.
    Young, RA., Bloom, BR., Davis, RW. (1990). US Patent 4,906,742. [USPTO]

  81. System for efficient isolation of genes using probes.
    Davis, RW., Young, RA. (1988). US Patent 4,788,135. [USPTO]

  82. Rennin-containing disrupted yeast cells used in cheese manufacture.
    Botstein, D., Fink, GR., Davis, RW. (1987). US Patent 4,695,470. [USPTO]

  83. GAL1 yeast promoter linked to non galactokinase gene.
    Botstein, D., Davis, RW., Fink, DR., Taunton-Rigby, A., Knowlton, RG., Mao, J.,Moir, DT., Goff, CG. (1987). US Patent 4,661,454. [USPTO]