Methods and apparatus for magnetic separation of cells. Davis, RW., Jeffrey, SS., Mindrinos, MN., Pease, RF., Powell, AA., Hajhossein,Talasaz, A. (2011). US Patent 8,071,395 [USPTO]
Precircle probe nucleic acid amplification methods.
Willis, TD. Hardenbol, P. Jain, M. Stolc, V. Ronaghi, M. Davis, RW . (2011). US Patent 7,993,880 [USPTO]
Charge perturbation detection system for DNA and other molecules.
Pourmand, N. Karhanek, M. Davis, RW. (2011). US Patent 8,012,75 [USPTO]
Rapid, informative diagnostic assay for influenza viruses including H5N1.
Pourmand, N., Diamond, L., Kumm, J., Davis, RW. (2011). US Patent 7,989,185 [USPTO]
Methods and compositions for use in analyte detection using proximity probes. Fredriksson, S., Davis, RW. (2011). US Patent 7,914,987. [USPTO]
Method to produce single stranded DNA of defined length and sequence and DNA probes produced thereby.
Mindrinos, M., Krishnakumar, S., Davis, RW. (2011). US Patent 7,897,747. [USPTO]
Multiplexed assay and probes for identification of HPV types.
Pourmand, N., Gharizadeh, B., Davis, RW. (2011). US Patent 7,875,428. [USPTO]
Charge perturbation detection system for DNA and other molecules.
Pourmand, N., Davis, RW., Karhanek, M. (2010). US Patent 7,785,785. [USPTO]
Method for detecting and amplifying target DNA.
Willis, TD., Hardenbol, P., Jain, M., Stolc, V., Davis, RW. (2010). US Patent 7,700,323. [USPTO]
Renaturation, reassociation, association and hybridization of nucleic acid molecules.
Namsaraev, E., Davis, RW., Karlin-Neumann, G. (2009). US Patent 7,482,125. [USPTO]
DNA fingerprinting using a branch migration assay.
Pourmand, N., Davis, RW., Wang, SX. (2009). US Patent 7,501,253. [USPTO]
DNA fingerprinting using a branch migration assay.
Pourmand, N., Davis, RW., Wang, SX. (2007). US Patent 7,238,486. [USPTO]
Renaturation, reassociation, association and hybridization of nucleic acid molecules.
Namsaraev, E., Davis, RW., Karlin-Neumann, G. (2006). US Patent 7,129,044. [USPTO]
Direct multiplex characterization of genomic DNA.
Willis, T.D., Hardenbol, P., Jain, M., Stolc, V., Ronaghi, M., Davis, R.W. (2005). United States Patent 6,858,412. [USPTO]
Dimeric fluorescent polypeptides.
Davis, R.W. Vaillancourt, P. (2005). US Patent US Patent 6,936,428. [USPTO]
Identification of drugs and drug targets by detection of the stress response.
Davis, R.W., Giaever, G. (2004). United States Patent 6,743,583. [USPTO]
Polypeptides from Chlamydia pneumoniae and their use in the diagnosis, prevention and treatment of disease.
Stephens, R.S., Mitchell, W., Kalman, S.S., Davis, R.W. (2004). US Patent 6,822,071. [USPTO]
Selecting tag nucleic acids.
Morris, M.S., Shoemaker, D.D., Davis, R.W. Mittmann, M.P. (2002). US Patent 6,458,530. [USPTO]
Recombinant mycobacteria.
Bloom, B.R., Davis, R.W., Jacobs, Jr., R., Young, R.A., Husson, R.N. (2002). US Patent 6,372,478. [USPTO]
Highly parallel and sensitive method for identifying drugs and drug targets.
Davis, R.W., Giaever, G.N., Shoemaker D., (2000). United States Patent 6,046,002. [USPTO]
Mycobacteriophages and uses thereof.
Bloom, B.R., Davis; R.W., Jacobs, Jr., W.R., Young, R.A., Husson, R.N. (1999). US Patent 5,968,733. [USPTO]
Cleaved amplified RFLP detection methods.
Ausubel, F., Davis, R.W., Preuss, D. (1999). US Patent, 6,004,783. [USPTO]
Electrophoresis using contour-clamped electric fields.
Chu, G., Vollrath, D., Davis, R., (1996). US Patent 5,549,796. [USPTO]
Method for detecting a nucleotide at a specific location within a nucleic acid using exonuclease activity.
Davis, R.W., Myles, A. (1995). US Patent 5,391,480. [USPTO]
Electrophoresis using contour-clamped electric fields.
Chu, G., Vollrath, D., Davis, RW. (1992). US Patent 5,165,898. [USPTO]
Use of the GAL1 yeast promoter.
Botstein, D., Davis, RW., Fink, GR., Taunton-Rigby, A., Knowlton, RG., Mao, J., Moir, DT., Goff, CG. (1992). US Patent 5,139,936. [USPTO]
Encoding antigens of M. Leprae.
Young, RA., Bloom, BR., Davis, RW. (1990). US Patent 4,906,742. [USPTO]
System for efficient isolation of genes using probes.
Davis, RW., Young, RA. (1988). US Patent 4,788,135. [USPTO]
Rennin-containing disrupted yeast cells used in cheese manufacture.
Botstein, D., Fink, GR., Davis, RW. (1987). US Patent 4,695,470. [USPTO]
GAL1 yeast promoter linked to non galactokinase gene.
Botstein, D., Davis, RW., Fink, DR., Taunton-Rigby, A., Knowlton, RG., Mao, J.,Moir, DT., Goff, CG. (1987). US Patent 4,661,454. [USPTO]
Rapid, Informative Diagnostic Assay For Influenza Viruses Including H5N1.
Davis, RW. Diamond, L. Kumm, J. Pourmand, N. (2009). [Stanford Reference S06-155], [USPTO]
A touch-based multimodal and cryptographic bio-human–machine interface. Lin S, Zhu J, Yu W, Wang B, Sabet KA, Zhao Y, Cheng X, Jhojaiji H, Haisong L, Tan J, Milla C, Davis RW, Emaminejad S. Proceedings of the National Academy of Sciences.. 2022 April 1;119 (15). doi: https//dx.doi.org/10.1073/pnas.2201937119.
Modeling Brownian Microparticle Trajectories in Lab-on-a-Chip Devices with Time Varying Dielectrophoretic or Optical Forces. Zaman MA, Wu M, Padhy P, Jensen MA, Hesselink L, Davis RW. Micromachines. 2021 October 1; 12(10):1265. doi: https://doi.org/10.3390/mi12101265
A Comprehensive Examination of Severely Ill ME/CFS Patients. Chang, CJ, Hung LY, & Kogelnik AM, Kaufman D, Aiyar R, Chu A, Peng L, Wilhelmy J, & Tannenbaum L, Xiao W, Davis RW. 2021 September 9; 9(10):1290. doi: 10.3390/healthcare9101290
Microfluidic Point-of-Care Testing: Commerical Landscape and Future Directions. Shivangi S, Saha A, Davis RW. Front Bioeng Biotechnol. 2021 Jan 31; 602659. doi: 10.3389/fbioe.2020.602659
Statistics and its interface. Zhang Y, Ouyang Z, Qian W, Smith RD, Wong WH, Davis RW. International Press. 2020 July 31;13(4):465-474. doi: https//dx.doi.org/10.4310/SII.2020.v13.n4.a4.
Community members in activated sludge as determined by molecular probe technology.
Xu W, Brand VR, Suresh S, Jensen MA, Davis RW, Criddle CS, St.Onge RP, Hyman RW. 2020 January 1;168(115104). doi: https://doi.org/10.1016/j.watres.2019.115104.
Identification of polyketide biosynthetic gene clusters that harbor self-resistance target genes. Vandova GA, Nivina A, Khosla Ca, Davis RW, Fisher CR, Hillenmeyer ME. bioRxiv. 2020 June 2. doi: https://doi.org/10.1101/2020.06.01.128595.
Automated motion tracking and data extraction for red blood cell biomechanics. Kumar A, Schmidt BR, Sanchez ZAC, Yazar F, Davis RW, Ramasubramanian AK, Saha AK.Curr Protoc Cytom. 2020 Jun;93(1):e75. doi:10.1002/cpcy.75.
The IDO metabolic trap hypothesis for the etiology of ME/CFS. Kashi AA, Davis RW, Phair RD. Diagnostics (Basel). 2019 Jul 26;9(3). pii: E82. doi: 10.3390/diagnostics9030082.
A nanoelectronics-blood-based diagnostic biomarker for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
Esfandyarpour R, Kashi A, Nemat-Gorgani M, Wilhelmy J, Davis RW. Proc Natl Acad Sci U S A. 2019 May 21;116(21):10250-10257. doi: 10.1073/pnas.1901274116. Epub 2019 Apr 29.
Red blood cell deformability is diminished in patients with Chronic Fatigue Syndrome. Saha AK, Schmidt BR, Wilhelmy J, Nguyen V, Abugherir A, Do JK, Nemat-Gorgani M, Davis RW, Ramasubramanian AK. Clin Hemorheol Microcirc. 2019;71(1):113-116. doi: 10.3233/CH-180469.
A biosensor-based approach reveals links between efflux pump expression and cell cycle regulation in pleiotropic drug resistance of yeast.
Li J, Kolberg K, Schlecht U, St Onge RP, Aparicio AM, Horecka J, Davis RW, Hillenmeyer ME, Harvey CJB. J Biol Chem. 2019 Jan 25;294(4):1257-1266. doi: 10.1074/jbc.RA118.003904. Epub 2018 Dec 4.
Combining newborn metabolic and DNA analysis for second-tier testing of methylmalonic acidemia. Peng G, Shen P, Gandotra N, Le A, Fung E, Jelliffe-Pawlowski L, Davis RW, Enns GM, Zhao H, Cowan TM, Scharfe C. Genet Med. 2018 Sep 13. doi: 10.1038/s41436-018-0272-5.
Multiplexed precision genome editing with trackable genomic barcodes in yeast.
Roy KR, Smith JD, Vonesch SC, Lin G, Tu CS, Lederer AR, Chu A, Suresh S, Nguyuen M, Horecka J, Tripathi A, Burnett WT, Morgan MA, Schulz J, Orsley KM, Wei W, Aiyar RS, Davis RW, Bankaitis VA, Haber JE, Salit ML, St Onge RP, Steinmetz LM. Nat Biotechnol. 2018 Jul;36(6):512-520. doi: 10.1038/nbt.4137. Epub 2018 May 7.
HEx: A heterologous expression platform for the discovery of fungal natural products.
Harvey CJB, Tang M, Schlecht U, Horecka J, Fischer CR, Lin HC, Li J, Naughton B, Cherry J, Miranda M, Li YF, Chu AM, Hennessy JR, Vandova GA, Inglis D, Aiyar RS, Steinmetz LM, Davis RW, Medema MH, Sattely E, Khosla C, St Onge RP, Tang Y, Hillenmeyer ME. Sci Adv. 2018 Apr 11;4(4):eaar5459. doi: 10.1126/sciadv.aar5459. eCollection 2018 Apr.
Template-independent enzymatic oligonucleotide synthesis (TiEOS): Its history, prospects, and challenges.
Jensen MA, Davis RW. Biochemistry. 2018 Mar 27;57(12):1821-1832. doi: 10.1021/acs.biochem.7b00937. Epub 2018 Mar 13. Review.
Streamlined circular proximity ligation assay provides high stringency and compatibility with low-affinity antibodies. Jalil R, Horecka J, Swartz JR, Davis RW, Persson HHJ. Proc Natl Acad Sci U S A. 2018 Jan 16. doi: 10.1073/pnas.1718283115.
Quantitative analysis of protein interaction network dynamics in yeast. Celaj A, Schlecht U, Smith JD, Xu W, Suresh S, Miranda M, Aparicio AM, Proctor M, Davis RW, Roth FP, St Onge RP. Mol Syst Biol. 2017 Jul 13;13(7):934. doi: 10.15252/msb.20177532.
Autonomous sweat extraction and analysis applied to cystic fibrosis and glucose monitoring using a fully integrated wearable platform. Emaminejad S, Gao W, Wu E, Davies ZA, Nyein HYY, Challa S, Ryan SP, Fahad HM, Chen K, Shahpar Z, Talebi S, Milla C, Javey A, Davis RW. Proc Natl Acad Sci U S A. 2017 May 2;114(18):4625-30 doi: 10.1073/pnas.1701740114.
Heterologous expression of diverse propionyl-CoA carboxylases affects polyketide production in Escherichia coli. Vandova GA, O’Brien RV, Lowry B, Robbins TF, Fischer CR, Davis RW, Khosla C, Harvey CJB, Hillenmeyer ME. J Antibiot (Tokyo). 2017 Apr 12. doi: 10.1038/ja.2017.38.
Multifunctional, inexpensive, and reusable nanoparticle-printed biochip for cell manipulation and diagnosis. Esfandyarpour R, DiDonato MJ, Yang Y, Durmus NG, Harris JS, Davis RW. Proc Natl Acad Sci USA. 2017 Feb 21;114(8):E1306-E1315. doi: 10.1073/pnas.1621318114.
A method for high-throughput production of sequence-verified DNA libraries and strain collections.
Smith JD, Schlecht U, Xu W, Suresh S, Horecka J, Proctor MJ, Aiyar RS, Bennett RA, Chu A, Li YF, Roy K, Davis RW, Steinmetz LM, Hyman RW, Levy SF, St Onge RP. Mol Syst Biol. 2017 Feb 13;13(2):913. doi: 10.15252/msb.20167233.
Application of 3D printing for smart objects with embedded electronic sensors and systems. Ota H, Emaminejad S, Gao Y, Zhao A, Wu E, Challa S, Chen K, Fahad HM, Jha AK, Kiriya D, Gao W, Shiraki H, Morioka K, Ferguson AR, Healy KE, Davis RW, Javey A. Adv Mater. 2016;1(1600013):1-8. doi: 10.1002/admt.201600013.
Systematic Mapping of Chemical-Genetic Interactions in Saccharomyces cerevisiae. Suresh S, Schlecht U, Xu W, Bray W, Miranda M, Davis RW, Nislow C, Giaever G, Lokey RS, St Onge RP. Cold Spring Harb Protoc. 2016 Sep 1;2016(9):pdb.top077701. doi: 10.1101/pdb.top077701.
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