Highly specific circular prozimity ligation assay. Persson HHJ, Jalili R, Horecka, Davis RW. ; Leland Stanford Junior University, assignee. USA patent pulication 11530794. 2023
Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats. R Stoughton, Kapur R, Cohen BA, Shoemaker D, Davis RW, Toner M. ; Leland Stanford Junior University, assignee. USA Patent App. 17/850,599
Sorting biological and non-biological moieties using magnetic levitation. Baday, M, Durmus NG, Calamak S, Demirci U, Davis RW, Steinmentz, L, Yang J, Chinnasamy T, Tocchio A.. ; Leland Stanford Junior University, assignee. USA patent publication 11338290. 2022
Scalable method for isolation and sequence-verification of oligonucleotides for complex libraries. St. Onge RP, Schlecht U, Levy SF, Davis RW, Nader Pourmand, Miloslav Karhanek, Ronald W. Davis inventors; Leland Stanford Junior University, assignee. USA patent publication US 1082264110787661. 2020.
Haplotyping of HLA Loci with Ultra-deep shotgun Sequencing. Wang C, Mindrinos MN, Davis MM, Davis RW, Krishnakumar S, inventors; Leland Stanford Junior University, assignee. USA patent publication US20190002979. 2019.
Highly Specific Circular Proximity Ligation Assay. Persson HHJ, Roxana J, Horecka JL, Davis RW, inventors; Leland Stanford Junior University, assignee. USA patent publication US20190360025. 2019.
Rare Cell Analysis Using Sample Splitting and DNA Tags. Shoemaker, D, Toner, M, Kapur, R, Stoughton, RB, Davis RW, inventors; The General Hospital Corporation, GPB Scientific, LLCC, Verinata Health, Inc., The Leland Stanford Junior University, assignee. USA patent publication US20150232936. 2018.
Charge Perturbation Detection System for DNA and Other Molecules. Pourmand, N, Karhanek, M, Davis RW, inventors; Leland Stanford Junior University, assignee. USA patent publication US20180346971A1. 2018.
Sorting biological and non-biological moieties using magnetic levitation. Baday, M, Durmus, NG, Calamak, S, Demirci, U, Davis, RW, Steinmetz, L, Yang, J, Chinnasamy, T, Tocchio, A, inventors; Leland Stanford Junior University, assignee. USA patent publication US20180280977A1. 2018.
Autonomous sweat extraction and analysis using a fully-integrated wearable platform. Emaminejad, S, Milla, C, Gao, W, Javey, A, Wu, E, Davis, RW, inventors; University of California, Leland Stanford University, assignee. USA patent publication US20180070870. 2018.
Haplotying of HLA loci with ultra-deep shotgun sequencing. Wang, C, Mindrinos, MN, Davis, MM, Davis, RW, Krishnakumar, S, inventors; Leland Stanford Junior University, assignee. USA patent 9,920,370. 2018.
Wearable sensor arrays for in-situ body fluid analysis. Javey, A, Gao, W, Davis, RW, Emaminejad, S, inventors; The Regents of the University of California, The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent publication US2016053988. 2018.
Highly specific circular proximity ligation assay. Persson, HH, Jalili, R, Horecka, JL, Davis, RW, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent publication WO2018160397A1. 2018.
Apparatuses and methods for determining analyte charge. Paik, K, Persson, HHJ, Lau, BTC, Dutton, RW, Liu, Y, Davis, RW, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent publication US20170097332. 2018.
Dna-conjugated antibodies for improved antibody affinity and reduced antibody cross reactivity. Davis, RW, Hurlburt, N, Zahn, JM, Javanmard, M, Mok, JA, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent publication US20160146804. 2016.
Re-usable analyte detector and methods. Harris, JS, Davis, RW, Esfandyarpour, R, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent publication US20160320373. 2016.
Scalable method for isolation and sequence-verification of oligonucleotides from complex libraries. St Ong, RP, Schlecht, U, Levy, SF, Davis, RW, Horecka, J, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent publication US20160122748. 2016.
System and method for cell levitation and monitoring. Demirci, U, Ghiran, I, Tasoglu, S, Davis, RW, Steinmetz, L, Durmus NG, Tekin, HC, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent publication US20160370386. 2016.
Apparatus for magnetic separation of cells. Davis, RW, Jeffrey, SS, Mindrinos, MN, Pease, RF, Powell, AA, Talasaz, AH, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent 9,267,943. 2016.
Charge perturbation detection system for DNA and other molecules. Pourmand, N, Karhanek, M, Davis, RW, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent 9,228,971. 2016.
Software haplotying of hla loci. Wang, C, Mindrinos, MN, Davis, MM, Davis, RW, Krishnakumar, S, Konstantinos, B, Fernandez-Vina, MA, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. WIPO patent publication WO20156200701. 2016.
Rare cell analysis using sample splitting and DNA tags. Shoemaker, D, Kapur, R, Toner, M, Stoughton, R, Davis, RW, inventors; General Hospital Corp, GPB Scientific LLC, Verinata Health, assignee. USA patent publication US20150232936. 2015.
Method to produce single stranded DNA of defined length and sequence and DNA probes produced thereby. Mindrinos, M, Krishnakumar, S, Davis, RW, Shen, P, Scharfe, C, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent 8,795,968. 2014.
Charge perturbation detection method for DNA and other molecules.Pourmand, N, Karhanek, M, Davis, RW, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent 8,753,812. 2014.
Calorimeter sensor. Esandyarpour, H, Davis RW, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent 8,696,989. 2014.
Determination of fetal aneuploidy by quantification of genomic dna from mixed samples. Stoughton, R, Kapur, R, Mehmet, T, Shoemaker, D, Davis, RW, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent publication US20130288242. 2013.
Array-based bioactivated nanospore devices. Ronaghi, M, Talasaz, A, Davis, RW, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent 8,592,225. 2013.
Microfluidic devices for measurement or detection involving cells or biomolecules. Davis, RW, Javanmard, M, Mindrinos, M, Mok, J, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent 8,614,056. 2013.
Methods and compositions for use in analyte detection using proximity probes. Fredriksson, S, Davis RW, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent 8,580,504. 2013.
Precircle probe nucleic acid amplification methods (previously: Direct Multiplex Characterization of Genomic DNA ). Willis, T, Hardenbol, P, Jain, M, Stolc, V, Ronaghi, M, Davis, RW, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent 8,383,348. 2013.
Charge perturbation detection system for DNA and other molecules. Pourmand, N, Karhanek, M, Davis, RW, inventors; The Board of Trustees of the Leland Stanford Junior University, assignee. USA patent 8,313,907. 2012.
Methods and apparatus for magnetic separation of cells. Davis, RW., Jeffrey, SS., Mindrinos, MN., Pease, RF., Powell, AA., Hajhossein,Talasaz, A. (2011). US Patent 8,071,395 [USPTO]
Precircle probe nucleic acid amplification methods.
Willis, TD. Hardenbol, P. Jain, M. Stolc, V. Ronaghi, M. Davis, RW . (2011). US Patent 7,993,880 [USPTO]
Charge perturbation detection system for DNA and other molecules.
Pourmand, N. Karhanek, M. Davis, RW. (2011). US Patent 8,012,75 [USPTO]
Rapid, informative diagnostic assay for influenza viruses including H5N1.
Pourmand, N., Diamond, L., Kumm, J., Davis, RW. (2011). US Patent 7,989,185 [USPTO]
Methods and compositions for use in analyte detection using proximity probes. Fredriksson, S., Davis, RW. (2011). US Patent 7,914,987. [USPTO]
Method to produce single stranded DNA of defined length and sequence and DNA probes produced thereby.
Mindrinos, M., Krishnakumar, S., Davis, RW. (2011). US Patent 7,897,747. [USPTO]
Multiplexed assay and probes for identification of HPV types.
Pourmand, N., Gharizadeh, B., Davis, RW. (2011). US Patent 7,875,428. [USPTO]
Charge perturbation detection system for DNA and other molecules.
Pourmand, N., Davis, RW., Karhanek, M. (2010). US Patent 7,785,785. [USPTO]
Method for detecting and amplifying target DNA.
Willis, TD., Hardenbol, P., Jain, M., Stolc, V., Davis, RW. (2010). US Patent 7,700,323. [USPTO]
Renaturation, reassociation, association and hybridization of nucleic acid molecules.
Namsaraev, E., Davis, RW., Karlin-Neumann, G. (2009). US Patent 7,482,125. [USPTO]
DNA fingerprinting using a branch migration assay.
Pourmand, N., Davis, RW., Wang, SX. (2009). US Patent 7,501,253. [USPTO]
DNA fingerprinting using a branch migration assay.
Pourmand, N., Davis, RW., Wang, SX. (2007). US Patent 7,238,486. [USPTO]
Renaturation, reassociation, association and hybridization of nucleic acid molecules.
Namsaraev, E., Davis, RW., Karlin-Neumann, G. (2006). US Patent 7,129,044. [USPTO]
Direct multiplex characterization of genomic DNA.
Willis, T.D., Hardenbol, P., Jain, M., Stolc, V., Ronaghi, M., Davis, R.W. (2005). United States Patent 6,858,412. [USPTO]
Dimeric fluorescent polypeptides.
Davis, R.W. Vaillancourt, P. (2005). US Patent US Patent 6,936,428. [USPTO]
Identification of drugs and drug targets by detection of the stress response.
Davis, R.W., Giaever, G. (2004). United States Patent 6,743,583. [USPTO]
Polypeptides from Chlamydia pneumoniae and their use in the diagnosis, prevention and treatment of disease.
Stephens, R.S., Mitchell, W., Kalman, S.S., Davis, R.W. (2004). US Patent 6,822,071. [USPTO]
Selecting tag nucleic acids.
Morris, M.S., Shoemaker, D.D., Davis, R.W. Mittmann, M.P. (2002). US Patent 6,458,530. [USPTO]
Recombinant mycobacteria.
Bloom, B.R., Davis, R.W., Jacobs, Jr., R., Young, R.A., Husson, R.N. (2002). US Patent 6,372,478. [USPTO]
Highly parallel and sensitive method for identifying drugs and drug targets.
Davis, R.W., Giaever, G.N., Shoemaker D., (2000). United States Patent 6,046,002. [USPTO]
Mycobacteriophages and uses thereof.
Bloom, B.R., Davis; R.W., Jacobs, Jr., W.R., Young, R.A., Husson, R.N. (1999). US Patent 5,968,733. [USPTO]
Cleaved amplified RFLP detection methods.
Ausubel, F., Davis, R.W., Preuss, D. (1999). US Patent, 6,004,783. [USPTO]
Electrophoresis using contour-clamped electric fields.
Chu, G., Vollrath, D., Davis, R., (1996). US Patent 5,549,796. [USPTO]
Method for detecting a nucleotide at a specific location within a nucleic acid using exonuclease activity.
Davis, R.W., Myles, A. (1995). US Patent 5,391,480. [USPTO]
Electrophoresis using contour-clamped electric fields.
Chu, G., Vollrath, D., Davis, RW. (1992). US Patent 5,165,898. [USPTO]
Use of the GAL1 yeast promoter.
Botstein, D., Davis, RW., Fink, GR., Taunton-Rigby, A., Knowlton, RG., Mao, J., Moir, DT., Goff, CG. (1992). US Patent 5,139,936. [USPTO]
Encoding antigens of M. Leprae.
Young, RA., Bloom, BR., Davis, RW. (1990). US Patent 4,906,742. [USPTO]
System for efficient isolation of genes using probes.
Davis, RW., Young, RA. (1988). US Patent 4,788,135. [USPTO]
Rennin-containing disrupted yeast cells used in cheese manufacture.
Botstein, D., Fink, GR., Davis, RW. (1987). US Patent 4,695,470. [USPTO]
GAL1 yeast promoter linked to non galactokinase gene.
Botstein, D., Davis, RW., Fink, DR., Taunton-Rigby, A., Knowlton, RG., Mao, J.,Moir, DT., Goff, CG. (1987). US Patent 4,661,454. [USPTO]
Spectral tweezers: Single sample spectroscopy using optoelectronic tweezers, Zaman, M. A., Wu, M., Ren, W., Jensen, M. A., Davis, R. W., and Hesselink, L. (2024) Appl Phys Lett 124, 071104.
Resolution improvement of optoelectronic tweezers using patterned electrodes. Zaman MA, Wu M, Ren W, Jensen MA, Davis RW, Hesselink L. Appl Phys Lett. 2023 Jul 24;123(4):041104. doi: 10.1063/5.0160939. Epub 2023 Jul 25. PubMed PMID: 37502178; PubMed Central PMCID: PMC10371355.
Catalytic Antibodies May Contribute to Demyelination in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Jensen, M. A., Dafoe, M. L., Wilhelmy, J., Cervantes, L., Okumu, A. N., Kipp, L., Nemat-Gorgani, M, and Davis, R. W. (2023). Biochemistry, 63(1), 9-18.
Phenotypic characteristics of peripheral immune cells of Myalgic encephalomyelitis/chronic fatigue syndrome via transmission electron microscopy: A pilot study. Jahanbani F, Maynard RD, Sing JC, Jahanbani S, Perrino JJ, Spacek DV, Davis RW, Snyder MP. Public Library of Science 2022 August 9, 17 (8) Plos one 17.8 (2022): e0272703.
Bead-Droplet Reactor for High-Fidelity Solid-Phase Enzymatic DNA Synthesis. Padhy, P., Zaman, M.A., Jensen, M.A., Cheng, Y.T., Huang, Y., Galambos, L., Davis, R.W. and Hesselink, L., 2022. arXiv preprint arXiv:2211.06799.
Controlled transport of individual microparticles using dielectrophoresis. Zaman, M.A., Padhy, P., Wu, M., Ren, W., Jensen, M.A., Davis, R.W. and Hesselink, L., 2022. Langmuir, 39(1), pp.101-110.
Bead Encapsulation and Ejection from Droplet for Solid-Phase Synthesis. Padhy, P., Zaman, M., Jensen, M., Cheng, Y.T., Galambos, L., Davis, R. and Hesselink, L., 2023. Bulletin of the American Physical Society.
Microparticle electrical conductivity measurement using optoelectronic tweezers. Ren, W., Zaman, M.A., Wu, M., Jensen, M.A., Davis, R.W. and Hesselink, L., 2023. Journal of Applied Physics, 134(11). https://doi.org/10.1063/5.0169565
Development of an RPA for Prediction of Radiation Necrosis Following Single Fraction Gamma Knife Radiosurgery for Brain Metastases. Mayo, Z.S., Reddy, C.A., Billena, C., Davies, E.M., Bommireddy, A., Davis, R.W., Murphy, E.S., Suh, J.H., Balagamwala, E.H., Chan, T.A. and Yu, J.S., 2023.International Journal of Radiation Oncology, Biology, Physics, 117(2), p.e137.
A touch-based multimodal and cryptographic bio-human–machine interface. Lin S, Zhu J, Yu W, Wang B, Sabet KA, Zhao Y, Cheng X, Jhojaiji H, Haisong L, Tan J, Milla C, Davis RW, Emaminejad S. Proceedings of the National Academy of Sciences.. 2022 April 1;119 (15). doi: https//dx.doi.org/10.1073/pnas.2201937119.
Modeling Brownian Microparticle Trajectories in Lab-on-a-Chip Devices with Time Varying Dielectrophoretic or Optical Forces. Zaman MA, Wu M, Padhy P, Jensen MA, Hesselink L, Davis RW. Micromachines. 2021 October 1; 12(10):1265. doi: https://doi.org/10.3390/mi12101265
A Comprehensive Examination of Severely Ill ME/CFS Patients. Chang, CJ, Hung LY, & Kogelnik AM, Kaufman D, Aiyar R, Chu A, Peng L, Wilhelmy J, & Tannenbaum L, Xiao W, Davis RW. 2021 September 9; 9(10):1290. doi: 10.3390/healthcare9101290
Microfluidic Point-of-Care Testing: Commerical Landscape and Future Directions. Shivangi S, Saha A, Davis RW. Front Bioeng Biotechnol. 2021 Jan 31; 602659. doi: 10.3389/fbioe.2020.602659
Statistics and its interface. Zhang Y, Ouyang Z, Qian W, Smith RD, Wong WH, Davis RW. International Press. 2020 July 31;13(4):465-474. doi: https//dx.doi.org/10.4310/SII.2020.v13.n4.a4.
Identification of polyketide biosynthetic gene clusters that harbor self-resistance target genes. Vandova GA, Nivina A, Khosla Ca, Davis RW, Fisher CR, Hillenmeyer ME. bioRxiv. 2020 June 2. doi: https://doi.org/10.1101/2020.06.01.128595.
Automated motion tracking and data extraction for red blood cell biomechanics. Kumar A, Schmidt BR, Sanchez ZAC, Yazar F, Davis RW, Ramasubramanian AK, Saha AK.Curr Protoc Cytom. 2020 Jun;93(1):e75. doi:10.1002/cpcy.75.
Community members in activated sludge as determined by molecular probe technology.
Xu W, Brand VR, Suresh S, Jensen MA, Davis RW, Criddle CS, St.Onge RP, Hyman RW. 2020 January 1;168(115104). doi: https://doi.org/10.1016/j.watres.2019.115104.
The IDO metabolic trap hypothesis for the etiology of ME/CFS. Kashi AA, Davis RW, Phair RD. Diagnostics (Basel). 2019 Jul 26;9(3). pii: E82. doi: 10.3390/diagnostics9030082.
A nanoelectronics-blood-based diagnostic biomarker for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
Esfandyarpour R, Kashi A, Nemat-Gorgani M, Wilhelmy J, Davis RW. Proc Natl Acad Sci U S A. 2019 May 21;116(21):10250-10257. doi: 10.1073/pnas.1901274116. Epub 2019 Apr 29.
Red blood cell deformability is diminished in patients with Chronic Fatigue Syndrome. Saha AK, Schmidt BR, Wilhelmy J, Nguyen V, Abugherir A, Do JK, Nemat-Gorgani M, Davis RW, Ramasubramanian AK. Clin Hemorheol Microcirc. 2019;71(1):113-116. doi: 10.3233/CH-180469.
A biosensor-based approach reveals links between efflux pump expression and cell cycle regulation in pleiotropic drug resistance of yeast.
Li J, Kolberg K, Schlecht U, St Onge RP, Aparicio AM, Horecka J, Davis RW, Hillenmeyer ME, Harvey CJB. J Biol Chem. 2019 Jan 25;294(4):1257-1266. doi: 10.1074/jbc.RA118.003904. Epub 2018 Dec 4.
Combining newborn metabolic and DNA analysis for second-tier testing of methylmalonic acidemia. Peng G, Shen P, Gandotra N, Le A, Fung E, Jelliffe-Pawlowski L, Davis RW, Enns GM, Zhao H, Cowan TM, Scharfe C. Genet Med. 2018 Sep 13. doi: 10.1038/s41436-018-0272-5.
Multiplexed precision genome editing with trackable genomic barcodes in yeast.
Roy KR, Smith JD, Vonesch SC, Lin G, Tu CS, Lederer AR, Chu A, Suresh S, Nguyuen M, Horecka J, Tripathi A, Burnett WT, Morgan MA, Schulz J, Orsley KM, Wei W, Aiyar RS, Davis RW, Bankaitis VA, Haber JE, Salit ML, St Onge RP, Steinmetz LM. Nat Biotechnol. 2018 Jul;36(6):512-520. doi: 10.1038/nbt.4137. Epub 2018 May 7.
HEx: A heterologous expression platform for the discovery of fungal natural products.
Harvey CJB, Tang M, Schlecht U, Horecka J, Fischer CR, Lin HC, Li J, Naughton B, Cherry J, Miranda M, Li YF, Chu AM, Hennessy JR, Vandova GA, Inglis D, Aiyar RS, Steinmetz LM, Davis RW, Medema MH, Sattely E, Khosla C, St Onge RP, Tang Y, Hillenmeyer ME. Sci Adv. 2018 Apr 11;4(4):eaar5459. doi: 10.1126/sciadv.aar5459. eCollection 2018 Apr.
Template-independent enzymatic oligonucleotide synthesis (TiEOS): Its history, prospects, and challenges.
Jensen MA, Davis RW. Biochemistry. 2018 Mar 27;57(12):1821-1832. doi: 10.1021/acs.biochem.7b00937. Epub 2018 Mar 13. Review.
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