Lewei Zhao, PhD
Biography
Lewei Zhao grew up in Xianyang, Shaanxi Province in China. He obtained his bachelor's degree in Hongyi Mathematics Honors Class from Wuhan University China in 2014. He went on to pursue a PhD from Wayne State University, Detroit, in 2019 in Applied and Computational Mathematics. He later joined Beaumont Proton Therapy Center from 2019 to 2023 as a Postdoctoral Scholar. During his postdoc, he completed the CAMPEP accredited medical physics certificate program offered at Wayne state University (2021-2022). His research interest is mathematical applications in medical physics.
Lewei joined the Stanford University Medical Physics Residency in 2023.
Publications
Mein, S., ……, Zhao, L. & Ding, X. (2024). Particle arc therapy: Status and potential. Radiotherapy and Oncology. https://doi.org/10.1016/j.radonc.2024.110434
Fan, Q., Zhao, L., Li, X., Hu, J., Lu, X., Yang, Z., Zhang, S., Yang, K., Ding, X., Liu, G., & Dai, S. (2024). A novel fast robust optimization algorithm for intensity-modulated proton therapy (IMPT) with minimum monitor unit constraint. Med Phys. https://doi.org/10.1002/mp.17285
Liu. P., Zhao. L, Liu, G., Cong, X., Li. X., & Ding, X. (2024). The first investigation of the dosimetric perturbations from the spot position errors in Spot-Scanning Proton Arc therapy (SPArc). Physics in Medicine and Biology. https://doi.org/10.1088/1361-6560/ad5827
Fan, Q., Zhang, X., Dao, R., Qian, Y., Zhao, L., Li, X., Ding, X., Liu. G., & Dai, S. (2024) Optimizing linear energy transfer distribution in IMPT using the alternating direction method of multipliers (ADMM). https://doi.org/10.3389/fonc.2024.1328147
Liu, G., Fan, Q., Zhao, L., Liu, P., Cong, X., Yan, D., Li. X. & Ding, X. (2024) First direct machine-specific parameters incorporated in Spot-Scanning Proton Arc therapy (SPArc) optimization algorithm. Med Phys. https://doi.org/10.1002/mp.16985
Liu, G., Zhao, L.(equal contribute to first author), Liu, P., Yan, D., Deraniyagala, R., Stevens, C., Li, X. & Ding, X. (2023). Development of a standalone delivery sequence model for proton arc therapy. Med Phys. https://doi.org/10.1002/mp.16879
Liu, G., Zhao, L.(equal contribute to first author), Liu, P., Dao, R., Qian, Y., Cong, X., Janssens, G., Li, X. & Ding, X. (2023). The first investigation of SPArc delivery time and accuracy with different delivery tolerance window settings. Physics in Medicine and Biology.
https://doi.org/10.1088/1361-6560/acfec5Liu, G., Zhao, L., Li, X., Zhang, S., Dai, S., Lu, X., & Ding, X. (2023). A novel ultrahigh-dose-rate proton therapy technology: spot-scanning proton arc therapy+ FLASH (SPLASH). International Journal of Radiation Oncology* Biology* Physics. https://doi.org/10.1016/j.ijrobp.2023.05.012
Clark, M., Ding, X., Zhao, L., Pogue, B., Gladstone, D., Rahman, M., ... & Bruza, P. (2023). Ultra-fast, high spatial resolution single-pulse scintillation imaging of synchrocyclotron pencil beam scanning proton delivery. Physics in Medicine & Biology, 68(4), 045016. https://doi.org/10.1088/1361-6560/acb753
Zhao, L., You, J., Liu, G., Wuyckens, S., Lu, X., & Ding, X. (2023). The first direct method of spot sparsity optimization for proton arc therapy. Acta Oncologica, 62(1), 48-52. https://doi.org/10.1080/0284186X.2023.2172689
Chang, S., Liu, G., Zhao, L., Zheng, W., Yan, D., Chen, P., ... & Ding, X. (2022). Introduce a rotational robust optimization framework for spot-scanning proton arc (SPArc) therapy. Physics in Medicine & Biology, 68(1), 01NT02. https://doi.org/10.1088/1361-6560/aca874
Wuyckens, S., Zhao, L., Saint-Guillain, M., Janssens, G., Sterpin, E., Souris, K., ... & Lee, J. A. (2022). Bi-criteria Pareto optimization to balance irradiation time and dosimetric objectives in proton arc therapy. Physics in Medicine & Biology, 67(24), 245017. https://doi.org/10.1088/1361-6560/aca5e9
Wang, W. G., Qin, A., Li, X., Zhou, J., Yan, D., Liu, G., Zhao, L., ... & Ding, X. (2022). Establish a comprehensive plan robustness evaluation platform for intensity modulated proton therapy for bilateral head and neck cancer based on the daily cone-beam computed tomography: a dose accumulation study between the PTV based IMPT (PTV-IMPT) and CTV based robust optimized IMPT (ro-IMPT) planning strategies. Therapeutic Radiology and Oncology, 6, 9. https://doi.org/10.21037/tro-21-42
Zhao, L.(Corresponding author), Liu, G., Li, X., & Ding, X. (2022). An evolutionary optimization algorithm for proton arc therapy. Physics in Medicine & Biology, 67(16), 16NT01. https://doi.org/10.1088/1361-6560/ac8411
Chang, S., Liu, G., Zhao, L., Zheng, W., Yan, D., Chen, P., ... & Ding, X. (2022). Redefine the role of spot-scanning proton beam therapy for the single brain metastasis stereotactic radiosurgery. Frontiers in oncology, 12, 804036. https://doi.org/10.3389/fonc.2022.804036
Wuyckens, S., Saint-Guillain, M., Janssens, G., Zhao, L., Li, X., Ding, X., ... & Souris, K. (2022). Treatment planning in arc proton therapy: Comparison of several optimization problem statements and their corresponding solvers. Computers in biology and medicine, 148, 105609. https://doi.org/10.1016/j.compbiomed.2022.105609
Zhao, L., Liu, G., Chen, S., Shen, J., Zheng, W., Qin, A., ... & Ding, X. (2022). Developing an accurate model of spot-scanning treatment delivery time and sequence for a compact superconducting synchrocyclotron proton therapy system. Radiation Oncology, 17(1), 87. https://doi.org/10.1186/s13014-022-02055-w
Zhao, L., Liu, G., Zheng, W., Shen, J., Lee, A., Yan, D., ... & Ding, X. (2022). Building a precise machine-specific time structure of the spot and energy delivery model for a cyclotron-based proton therapy system. Physics in Medicine & Biology, 67(1), 01NT01. https://doi.org/10.1088/1361-6560/ac431c
Jia, C., Zhang, Z., & Zhao, L. (Corresponding author) (2021). Two-parameter localization for eigenfunctions of a Schrödinger operator in balls and spherical shells. Journal of Mathematical Physics, 62(9). https://doi.org/10.1063/5.0023250
Li, H., Wan, X., Yin, P., & Zhao, L. (authors in alphabetical order) (2021). Regularity and finite element approximation for two-dimensional elliptic equations with line Dirac sources. Journal of Computational and Applied Mathematics, 393, 113518. https://doi.org/10.1016/j.cam.2021.113518
Liu, G., Zhao, L., Qin, A., Grills, I., Deraniyagala, R., Stevens, C., ... & Ding, X. (2021). Lung stereotactic body radiotherapy (SBRT) using spot-scanning proton arc (SPArc) therapy: a feasibility study. Frontiers in oncology, 11, 664455. https://doi.org/10.3389/fonc.2021.664455
Liu, G., Li, X., Qin, A., Zhou, J., Zheng, W., Zhao, L., ... & Ding, X. (2021). Is proton beam therapy ready for single fraction spine SBRS?–a feasibility study to use spot-scanning proton arc (SPArc) therapy to improve the robustness and dosimetric plan quality. Acta Oncologica, 60(5), 653-657. https://doi.org/10.1080/0284186x.2021.1892183
He, Y., & Zhao, L. (authors in alphabetical order) (2021). Investigation of instability in ultrasonic welding under parametric excitation. The International Journal of Electrical Engineering & Education, 0020720920983508. https://doi.org/10.1177/0020720920983508
Chang, S., Liu, G., Zhao, L., Dilworth, J. T., Zheng, W., Jawad, S., ... & Ding, X. (2020). Feasibility study: spot-scanning proton arc therapy (SPArc) for left-sided whole breast radiotherapy. Radiation Oncology, 15, 1-11. https://doi.org/10.1186/s13014-020-01676-3
Liu, G., Li, X., Zhao, L., Zheng, W., Qin, A., Zhang, S., ... & Ding, X. (2020). A novel energy sequence optimization algorithm for efficient spot-scanning proton arc (SPArc) treatment delivery. Acta Oncologica, 59(10), 1178-1185. https://doi.org/10.1080/0284186x.2020.1765415
Pan, H., Zhang, Z., & Zhao, L. (Corresponding author) (2020). Some new developments of polynomial preserving recovery (PPR) on hexagon and chevron patterns, International Journal of Numerical Analysis and Modeling, 17(3), 390-403. https://www.global-sci.org/intro/article_detail/ijnam/16865.html
An, J., Zhao, L., & Zhang, W. Z. (2020). A high-precision numerical method for the dissipative dynamics of the Hamiltonian systems. International Journal of Computer Mathematics, 97(12), 2436-2450. https://doi.org/10.1080/00207160.2019.1701663