Research Symposium

Stanford Medicine Children’s Health Center for IBD and Celiac Disease Research Symposium

This symposium will focus on the translational research and clinical discussions at the forefront of pediatric IBD and celiac disease. Faculty, trainees, postdocs, students, and staff are invited to learn more about the latest developments, innovations, and advancements in the diagnosis, management, and therapy for both pediatric IBD and celiac disease.

Join us at this in-person event on October 29 from 9:00am-3:00pm PST!

This year’s symposium will also feature abstracts and a poster hall from our Intramural Seed Grant and Postdoc/Early Career Support awardees who are making an impact in pediatric IBD and celiac disease.

This event is free and open to all.

09:00 AM - 03:00 PM

Tuesday, October 29, 2024

Li Ka Shing Center, Berg Hall

Learn, network, and brainstorm on innovative research across the translational spectrum for pediatric inflammatory bowel disease (IBD) and celiac disease.

Call for Abstracts: Due Oct 4th, 11:59PM PST

Please join us at the Stanford Medicine Children’s Health Center for IBD and Celiac Disease 3rd Annual Research Symposium by not only attending and learning from leading experts in the field but also presenting your research and connecting with the Stanford scientific community.

We welcome abstracts in all areas relevant to children and young adults with intestinal inflammation, including but not limited to:

• Microbiome
• Epithelial Biology
• Immunology
• Genetics
• Clinical and Outcomes Research
• Data Science
• Epidemiology
• Community-Based Research

If you are interested in submitting an abstract, please do so here: http://bit.ly/3XSEOAF.

Program

08:30AM Continental Breakfast

09:00AM Opening Remarks

• Michael J. Rosen, MD, MSCI, Stanford University Endowed Professor for Pediatric IBD and Celiac Disease; Director, Center for Pediatric IBD and Celiac Disease
• Mary Leonard, MD, MSCE, Arline and Pete Harman Professor of Pediatrics; Chair, Department of Pediatrics

09:15AM-10:15AM Host-Microbe and Intercellular Interactions in IBD and Mucosal Immunity

• Moderator: Stephan Rogalla, MD, PhD, Clinical Assistant Professor of Medicine (Gastroenterology & Hepatology)

09:15AM The Impact of Commensal Eukaryotes on Mucosal Immunity and their implications for IBD Severity

• Michael Howitt, PhD, Assistant Professor of Pathology and of Microbiology and Immunology

09:45AM Single-cell and Spatial Multi-omics to Understand Epithelial Injury in IBD

• Michael Kattah, MD, PhD, Assistant Professor of Medicine, UCSF

10:15AM AM BREAK 

10:30AM-11:40AM Understanding Celiac Disease: Body, Mind, and Microbe

• Moderator: Elizabeth Mellins, MD, Professor of Pediatrics (Human Gene Therapy)

10:30AM Psychological Impacts of Celiac Disease

• Hilary Jericho, MD, MSCI, Clinical Associate Professor of Pediatric Gastroenterology; Director, Stanford Children's Health Celiac Disease Program

11:00AM Keynote Address: The Importance of Adequate Nutrition and The Intestinal Microbiota in the Balance Between Health and Disease Early In Life: The Celiac Disease Paradigm

• Alessio Fasano, MD, W. Allan Walker Chair in Pediatric Gastroenterology and Nutrition; Division Chief, Pediatric Gastroenterology and Nutrition; Director, Center for Celiac Research and Treatment; Director, Mucosal Immunology and Biology Research Center; Associate Chief for Basic, Clinical and Translational Research; Massachusetts General Hospital

11:40AM Refreshments Break

12:00PM-12:40PM The Future of IBD Care and Monitoring

• Moderator: Ruben Colman, MD, PhD, Instructor, Pediatrics- Gastroenterology

12:00PM Keynote Address: C. difficile and IBD

• Maria Oliva-Hemker, MD, Vice Dean for Faculty; Stermer Family Professor of Pediatric Inflammatory Bowel Disease; Division Chief, Pediatric Gastroenterology, Hepatology, and Nutrition; Professor of Pediatrics; Johns Hopkins University School of Medicine

12:40PM Transforming Healthcare with Deep Data and Remote Monitoring 

• Michael Snyder, PhD, Stanford W. Ascherman Professor of Genetics

01:10PM Closing Remarks

• Michael J. Rosen, MD, MSCI, Stanford University Endowed Professor for Pediatric IBD and Celiac Disease; Director, Center for Pediatric IBD and Celiac Disease

01:30 Boxed Lunch 

Program

07:30AM Continental Breakfast

08:15AM Opening Remarks

• Michael Rosen, MD, MSCI, Stanford University Endowed Professor for Pediatric IBD and Celiac Disease; Director, Stanford Medicine Children’s Health Center for IBD and Celiac Disease
• Mary Leonard, MD, MSCE, Arline and Pete Harman Professor of Pediatrics; Chair, Department of Pediatrics
• Sohail Husain, MD, Chambers-Okamura Endowed Professor of Pediatrics; Chief, Division of Gastroenterology, Hepatology, and Nutrition

08:30AM Keynote Address: Regulation of the host-microbiota relationship

• Introduction: Michael Rosen, MD, MSCI, Stanford University Endowed Professor for Pediatric IBD and Celiac Disease; Director, Stanford Medicine Children’s Health Center for IBD and Celiac Disease
• Theresa Alenghat, VMD, PhD, Associate Professor, Department of Pediatrics (Immunobiology), Cincinnati; Children’s Hospital Medical Center

09:15AM Human Autoimmunity

• Introduction: Michael Rosen, MD, MSCI, Stanford University Endowed Professor for Pediatric IBD and Celiac Disease; Director, Stanford Medicine Children’s Health Center for IBD and Celiac Disease
• Mark Davis, PhD, Burt and Marion Avery Family Professor of Microbiology & Immunology; Director, Stanford Institute for Immunity, Transplantation, and Infection 
  • The return of CD8 T cell suppression

09:40AM AM Break

10:00AM Influence of the Microbiome of Health & Disease

• Introduction: Michael Rosen, MD, MSCI, Stanford University Endowed Professor for Pediatric IBD and Celiac Disease; Director, Stanford Medicine Children’s Health Center for IBD and Celiac Disease
• Michael Fischbach, PhD, Associate Professor of Bioengineering and of Medicine
  • 10:10AM-10:35AM Understanding and manipulating immune modulation by the microbiome
• Justin Sonnenburg, PhD, Professor of Microbiology and Immunology
  • 10:35AM-11:00AM Gut microbiome industrialization and the rise of chronic inflammatory disease

11:00AM News Ways of Understanding the Immune Response in Celiac Disease

• Introduction: Nasim Khavari, MD, MPH, Clinical Associate Professor of Pediatrics (Gastroenterology, Hepatology, and Nutrition)
• Elizabeth Mellins, MD, Professor of Pediatrics (Human Gene Therapy)
  • 11:10AM-11:35AM MHCII antigen presentation in autoimmune disease: the celiac disease example
• Calvin Kuo, MD, PhD, Maureen Lyles D’Ambrogio Professor of Medicine (Hematology)
  • 11:35AM-12:00PM Using organoids to model celiac disease and IBD

12:00PM Poster Session & Lunch

01:00PM Immune Therapy and Profiling in IBD 

• Introduction: Alka Goyal, MD, Clinical Professor of Pediatrics (Gastroenterology, Hepatology, and Nutrition); Interim Associate Chief of Clinical Affairs, Division of Gastroenterology, Hepatology, and Nutrition
• Christopher Garcia, PhD, Younger Family Professor of Molecular & Cellular Physiology, and Structural Biology
  • 01:10PM-01:35PM Cytokine engineering for IBD
    • Presented by Robert A. Saxton, PhD, Assistant Professor of Immunology & Molecular Medicine    
• Rosa Bacchetta, MD, Associate Professor of Pediatrics (Stem Cell Transplantation Regenerative Medicine)  
  • 01:35PM-02:00PM Autologous engineered regulatory T cells for pediatric IBD
• Stephan Rogalla, MD, PhD, Clinical Assistant Professor of Medicine (Gastroenterology & Hepatology)
  • 02:00PM-02:25PM High-parameter spatial analysis to improve understanding in IBD
    

02:25PM PM Break

02:40PM Pediatric Gastroenterology Divison Research

• Introduction: Steven Levitte, MD, PhD, Postdoctoral Pediatric Medical Fellow (Gastroenterology, Hepatology, and Nutrition)
• Michael Rosen, MD, MSCI, Stanford University Endowed Professor for Pediatric IBD and Celiac Disease; Director, Stanford Medicine Children’s Health Center for IBD and Celiac Disease
  • Tissue molecular predictors of treatment response in pediatric ulcerative colitis
• Alka Goyal, MD, Clinical Professor of Pediatrics (Gastroenterology, Hepatology, and Nutrition); Interim Associate Chief of Clinical Affairs, Division of Gastroenterology, Hepatology, and Nutrition
  • Bench to bedside: Clinical research studies in IBD

03:40PM PM Break

03:55PM Novel Technologies for Assessing Intestinal Inflammation and Fibrosis

• Introduction: Dylan Dodd, MD, PhD, Assistant Professor of Pathology, of Microbiology & Immunology
• Tom Soh, MS, PhD, Professor of Radiology
  • 04:05PM-04:30PM Technology for continuously measuring specific molecules in vivo
• Jeong Hyun, MD, Assistant Professor of Surgery (Pediatrics)
  • 04:30PM-04:55PM Characterization of creeping fat in intestinal strictures in Crohn’s Disease    
• John Gubatan, MD, Instructor, Medicine (Gastroenterology & Hepatology)
  • 04:55PM-05:20PM Decoding the Adaptive Immune Repertoire with Machine Learning to Predict Biologic Therapy Outcomes in Patients with Pediatric Inflammatory Bowel

05:20PM Closing Remarks & Networking Session

06:00PM Program Ends