CAR-FACS

CAR-FACS is a high-dimensional flow cytometry assay for enumerating and phenotyping of  CAR-T cells in treated patients.

Patient specimen (PBMC, BM and CSF) are obtained at the bedside in real time. Cells are stained with a proprietary panel to detect the percentage of CAR-T cells. Many functions determining markers are detected on the same panel. In addition to T cells, many other cell types and biomarkers of response and toxicity are investigated in real-time. We leverage full spectrum cytometry, using the Cytek Aurora instrument to determine as many markers as possible in real-time. The volumetric acquisition facilitates real-time ALC determination.

For detailed panel information, please contact the CCSU Director at bsahaf@stanford.edu.

 

 

 

 

 

Target

Approved Treatments

CD19

Tescarta, Tecartus, Breyanzi, Kymriah
BCMA

ABECMA, Carvykti, Cilta-cel