Genome Technology Center

Exploiting the natural synergism between biology and technology

Our center develops new technologies to address important biological questions that otherwise would not be feasible. Our successes can involve improvements to existing technologies or completely new inventions, both of which aim to increase speed and accuracy while decreasing cost. In turn, once a new technology has been developed or advanced, it can often drive the perception of what is possible in the realm of experimental biology. Historically, this synergism between biology and technology has thrived at SGTC as applied to yeast functional genomics and large-scale sequencing efforts. In the next phase of our evolution we will use yeast as the test-bed of advanced technologies to enable novel solutions to the greatest challenges facing human health.

 

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Noteworthy

Duration: 1 min |

Standard Operating Procedures: A Video Training Series
made available online »

Ronald W. Davis
Director
Biography / Publications

Featured Topics

Human OligoGenome Resource
A database of oligonucleotide capture probes for resequencing target regions across the human genome.

Nucleic Acids Res. 2012 Jan;40(Database issue):D1137-43. Epub 2011 Nov 18.


Competitive Genomic Screens of Barcoded Yeast Libraries.
View full size video and article at JoVE

We have developed comprehensive, unbiased genome-wide screens to understand gene-drug and gene-environment interactions. Methods for screening these mutant collections are presented.
  View Article


 

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