Exploiting the natural synergism between biology and technologyOur center develops new technologies to address important biological questions that otherwise would not be feasible. Our successes can involve improvements to existing technologies or completely new inventions, both of which aim to increase speed and accuracy while decreasing cost. In turn, once a new technology has been developed or advanced, it can often drive the perception of what is possible in the realm of experimental biology. Historically, this synergism between biology and technology has thrived at SGTC as applied to yeast functional genomics and large-scale sequencing efforts. In the next phase of our evolution we will use yeast as the test-bed of advanced technologies to enable novel solutions to the greatest challenges facing human health.
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Noteworthy
Duration: 1 min | Standard Operating Procedures: A Video Training Series Ronald W. Davis Featured Topics A recent article in the New York Times highlights work by Massachusetts General Hospital researchers and Stanford genomics expert Ron Davis, PhD, in which the scientists presented "stunning evidence that the mouse model has been totally misleading for at least three major killers - sepsis, burns and trauma." Human OligoGenome Resource Competitive Genomic Screens of Barcoded Yeast Libraries We have developed comprehensive, unbiased genome-wide screens to understand gene-drug and gene-environment interactions. Methods for screening these mutant collections are presented.
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