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VA Palo Alto & Stanford
Dr. Kurella Tamura leads a health services research program addressing benefits and harms of chronic kidney disease treatments in real world populations, with special interest in dialysis and hypertension treatment. Her research utilizes clinical trials, cohort studies, and real world evidence methods, and has been supported by multiple NIH, VA, and foundation awards. She serves as an Associate Editor at the Clinical Journal of the American Society of Nephrology, on multiple NIDDK and VA Data Safety Monitoring Boards, and on the Advisory committees for the Clin-STAR and Beeson programs in transdisciplinary aging research. She has a strong commitment to mentoring trainees from the pre-medical stage through the post-doctoral and junior faculty ranks.
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority
study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study
conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia
will demonstrate the benefit of statins for reducing the primary composite of death,
dementia, and persistent disability and secondary composites including mild cognitive
impairment (MCI) and cardiovascular events.
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Improving Medical Decision Making for Older Patients With End Stage Renal Disease
The overall objective of this study is to reduce the burden of chronic kidney disease (CKD)
and its consequences for an aging U.S. population. To accomplish this, the investigators
propose to conduct a multi-center randomized trial of an advance care planning (ACP) video
intervention (vs. usual care) among older patients with CKD.