Catherine Aftandilian

Clinical Associate Professor, Pediatrics - Hematology & Oncology

Clinical Focus

Pediatric Hematology-Oncology
Leukemia
Relapsed leukemia
Infectious complication of oncology treatment
Fungal infections

Academic Appointments

Clinical Associate Professor, Pediatrics - Hematology & Oncology
Member, Maternal & Child Health Research Institute (MCHRI)
Member, Stanford Cancer Institute

Honors & Awards

AOA, Medical Honor Society (2007)
Fellow, Rachleff Hem-Onc Pediatric Fellowship fund (2012-2013)

Professional Education

Medical Education: Tufts University School of Medicine (2007) MA
Fellowship: Stanford University Pediatric Hematology Oncology Fellowship (2014) CA
Residency: Mass General Hospital for Children Pediatric Residency (2011) MA
Internship: Mass General Hospital for Children Pediatric Residency (2008) MA
Board Certification: American Board of Pediatrics, Pediatrics (2010)
Board Certification: American Board of Pediatrics, Pediatric Hematology-Oncology (2015)
Chief Resident, Massachusetts General Hospital for Children, Pediatrics (2011)
Resident, Massachusetts General Hospital for Children, Pediatrics (2010)
Doctor of Medicine, Tufts University School of Medicine (2007)

Contact

Clinical Pediatric Hematology and Oncology 300 Pasteur Dr Rm H314 MC 5208 Stanford CA 94305 Tel: (650) 723-5535 Fax: (650) 497-8001
Clinical Pediatric Hematology/Oncology 725 Welch Rd Palo Alto CA 94304 Tel: (650) 497-8953 Fax: (650) 497-8101

Current Research and Scholarly Interests

I am interested in the prevention and management of infectious complication in pediatric oncology patients. I am also interested in developing a protocol for the management of low risk patients with fever and neutropenia.

Clinical Trials

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections Recruiting
More
This study will establish a non-invasive diagnostic approach and evaluate clinical outcomes for children at high-risk for pulmonary invasive fungal infection (PIFI).
Lead Sponsor
Stanford Investigators
- Catherine Aftandilian
View full details
Phase I Dose Escalation Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies Recruiting
More
This phase I trial studies the best dose and side effects of CD19/CD22 chimeric antigen receptor (CAR) T cells when given together with chemotherapy, and to see how well they work in treating children or young adults with CD19 positive B acute lymphoblastic leukemia that has come back or does not respond to treatment. A CAR is a genetically-engineered receptor made so that immune cells (T cells) can attack cancer cells by recognizing and responding to the CD19/CD22 proteins. These proteins are commonly found on B acute lymphoblastic leukemia. Drugs used in chemotherapy, such as fludarabine phosphate and cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving CD19/CD22-CAR T cells and chemotherapy may work better in treating children or young adults with B acute lymphoblastic leukemia.
Lead Sponsor
Stanford Investigators
View full details
Home Away From Home - Quality of Life Surveys Recruiting
More
Treatment for pediatric acute myeloid leukemia (AML) involves intensive chemotherapy regimens that result in periods of profound neutropenia leaving patients susceptible to severe infectious complications. Infectious complications are the leading cause of treatment related mortality among AML patients, but there are little clinical data to inform whether management of neutropenia post AML chemotherapy should occur in an outpatient or inpatient setting. Further, no studies have been conducted that assess the impact of neutropenia management strategy on the quality of life of pediatric patients with AML and their caregivers.
Lead Sponsor
Stanford Investigators
- Catherine Aftandilian
View full details
Symptom Screening Linked to Care Pathways Recruiting
More
Most children with cancer survive because they are given intensive treatments, but unfortunately, these treatments are associated with distressing symptoms. To address this problem, we developed the Symptom Screening in Pediatrics Tool (SSPedi) so that children receiving cancer treatments can communicate their bothersome symptoms, and Supportive care Prioritization, Assessment and Recommendations for Kids (SPARK), a web-based application that links identified symptoms to supportive care guidelines for symptom management. To establish that these tools improve the lives of children newly diagnosed with cancer, we will conduct a trial that randomizes 20 pediatric cancer institutions and measures the impact of three times weekly symptom screening, symptom feedback to healthcare providers and the development of care pathways for symptom management to improve total symptom burden, fatigue and quality of life.
Lead Sponsor
Stanford Investigators
- Catherine Aftandilian
View full details

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