Thomas Koehnke

Senior Research Scientist-Basic Life, Stem Cell Bio Regenerative Med Institute

All Publications

Publications (47)

All Publications (47)
Journal Articles (35)
Conference Proceedings (12)

Profiles With Related Publications

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Ash A. Alizadeh, MD/PhD

Moghadam Family Professor
Clinical Focus
Cancer > Lymphoma, Lymphoma, B-Cell Chronic Lymphocytic Leukemia, Waldenstrom Macroglobulinemia, Burkitt Lymphoma, Follicular Lymphoma, Diffuse Large-Cell Lymphomas, Leukemia, Hairy Cell, Lymphoma, B-Cell, Marginal Zone, Hodgkin Disease, Medical Oncology
Research Interests
My research is focused on attaining a better understanding of the initiation, maintenance, and progression of tumors, and their response to current therapies toward improving future treatment strategies. In this effort, I employ tools from functional genomics, computational biology, molecular genetics, and mouse models.

Clinically, I specialize in the care of patients with lymphomas, working on translating our findings in prospective cancer clinical trials.

414 Total Publications
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Alice Bertaina MD, PhD

Lorry I. Lokey Professor
Clinical Focus
Pediatric Stem Cell Transplantation, Graft engineering, Pediatric Hematology-Oncology

201 Total Publications
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Agnieszka Czechowicz, MD, PhD

Assistant Professor of Pediatrics (Stem Cell Transplantation)
Research Interests
Dr. Czechowicz’s research is aimed at understanding how hematopoietic stem cells interact with their microenvironment in order to subsequently modulate these interactions to improve bone marrow transplantation and unlock biological secrets that further enable regenerative medicine broadly. This work can be applied across a variety of disease states ranging from rare genetic diseases, autoimmune diseases, solid organ transplantation, microbiome-augmentation and cancer.

54 Total Publications
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Gary Dahl

Professor of Pediatrics (Hematology/Oncology), Emeritus
Research Interests
Hematology/Oncology, Phase I drug studies for childhood cancer, overcoming multidrug resistance in leukemia and solid tumors, biology and treatment of acute nonlymphocytic leukemia, early detection of central nervous system leukemia by measuring growth, factor binding proteins.

171 Total Publications
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Amanda Dudek

Instructor, Pediatrics - Stem Cell Transplantation

16 Total Publications
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Edgar Engleman

Professor of Pathology and of Medicine (Immunology and Rheumatology)
Research Interests
Dendritic cells, macrophages, NK cells and T cells; functional proteins and genes; immunotherapeutic approaches to cancer, autoimmune disease, neurodegenerative disease and metabolic disease.

290 Total Publications
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Peter Greenberg

Professor of Medicine (Hematology), Emeritus
Clinical Focus
Cancer > Hematology, Hematology, Myelodysplastic Syndromes

341 Total Publications
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Siddhartha Jaiswal

Associate Professor of Pathology
Clinical Focus
Transfusion Medicine, Genomics and Molecular Pathology, Anatomic and Clinical Pathology
Research Interests
We identified a common disorder of aging called clonal hematopoiesis of indeterminate potential (CHIP). CHIP occurs due to certain somatic mutations in blood stem cells and represents a precursor state for blood cancer, but is also associated with increased risk of cardiovascular disease and death. We hope to understand more about the biology and clinical implications of CHIP using human and model system studies.

76 Total Publications
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Lea Lemaitre

Postdoctoral Scholar, Gastroenterology

9 Total Publications
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Sydney X. Lu

Assistant Professor of Medicine (Hematology)
Clinical Focus
Hematology

99 Total Publications
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Crystal Mackall

Ernest and Amelia Gallo Family Professor and Professor of Pediatrics and of Medicine
Research Interests
Recent clinical studies, by us and others, have demonstrated that genetically engineered T cells can eradicate cancers resistant to all other therapies. We are identifying new targets for these therapeutics, exploring pathways of resistance to current cell therapies and creating next generation platforms to overcome therapeutic resistance. We have discovered novel insights into the biology of human T cell exhaustion and developed approaches to prevent and reverse this phenomenon.

395 Total Publications
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Ravi Majeti MD, PhD

Director, Stanford Institute for Stem Cell Biology and Regenerative Medicine, Virginia and D. K. Ludwig Professor and Professor of Medicine (Hematology/Stem Cell Institute)
Research Interests
The Majeti lab focuses on the molecular/genomic characterization and therapeutic targeting of leukemia stem cells in human hematologic malignancies, particularly acute myeloid leukemia (AML). Our lab uses experimental hematology methods, stem cell assays, genome editing, and bioinformatics to define and investigate drivers of leukemia stem cell behavior. As part of these studies, we have led the development and application of robust xenotransplantation assays for human hematopoietic cells.

192 Total Publications