Thomas Koehnke

Instructor, Institute for Stem Cell Biology and Regenerative Medicine

Academic Appointments

Instructor, Institute for Stem Cell Biology and Regenerative Medicine

Professional Education

Fellowship, University Hospital of Munich (LMU), Munich, Germany, Medicine - Hematology/Oncology (2017)
Dr. med., Charité - University Medicine Berlin, Berlin, Germany, Medicine (2015)
Residency Training, University Hospital of Munich (LMU), Munich, Germany, Medicine - Hematology/Oncology (2013)
M.D., Georg-August-Universität Göttingen, Göttingen, Germany, Medicine (2010)

All Publications

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Ash A. Alizadeh, MD/PhD

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Cancer > Lymphoma, Lymphoma, B-Cell Chronic Lymphocytic Leukemia, Waldenstrom Macroglobulinemia, Burkitt Lymphoma, Follicular Lymphoma, Diffuse Large-Cell Lymphomas, Leukemia, Hairy Cell, Lymphoma, B-Cell, Marginal Zone, Hodgkin Disease, Medical Oncology
Research Interests
My research is focused on attaining a better understanding of the initiation, maintenance, and progression of tumors, and their response to current therapies toward improving future treatment strategies. In this effort, I employ tools from functional genomics, computational biology, molecular genetics, and mouse models.

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Dr. Czechowicz’s research is aimed at understanding how hematopoietic stem cells interact with their microenvironment in order to subsequently modulate these interactions to improve bone marrow transplantation and unlock biological secrets that further enable regenerative medicine broadly. This work can be applied across a variety of disease states ranging from rare genetic diseases, autoimmune diseases, solid organ transplantation, microbiome-augmentation and cancer.

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We identified a common disorder of aging called clonal hematopoiesis of indeterminate potential (CHIP). CHIP occurs due to certain somatic mutations in blood stem cells and represents a precursor state for blood cancer, but is also associated with increased risk of cardiovascular disease and death. We hope to understand more about the biology and clinical implications of CHIP using human and model system studies.

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Lea Lemaitre

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