Darren Salmi

All Publications

• Educational Case: Primary Osteosarcoma. Academic pathology Petriceks, A. H., Salmi, D. 2019; 6: 2374289518820337

  Abstract

  The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology. For additional information, and a full list of learning objectives for all three competencies, see http://journals.sagepub.com/doi/10.1177/2374289517715040.

  View details for PubMedID 30733995

• Trends in Pathology Graduate Medical Education Programs and Positions, 2001 to 2017 ACADEMIC PATHOLOGY Petriceks, A. H., Salmi, D. 2018; 5: 2374289518765457

  Abstract

  The US medical workforce is facing an impending physician shortage. This shortage holds special concern for pathologists, as many senior practitioners are set to retire in the coming years. Indeed, studies indicate a "pathologist gap" may grow through 2030. As such, it is important to understand current and future trends in US pathology. One key factor is graduate medical education. In this study, we analyzed data from the Accreditation Council of Graduate Medical Education, to determine the change in pathology graduate medical education programs and positions, from 2001 to 2017. We found that pathology programs and positions have increased since the 2001 to 2002 academic year, even after adjusting for population growth. However, this increase is much lower than that of total graduate medical education. Furthermore, many pathology subspecialties have declined in population-adjusted levels. Other subspecialties, such as selective pathology, have grown disproportionately. Our findings may be valuable for understanding the state of US pathology, now and in the future. They imply that more resources-or technological innovations-may be needed for specific pathology programs, in hopes of closing the pathologist gap for both this specialty and its subspecialties.

  View details for PubMedID 29623293

• Educational Case: Symptomatic but Unruptured Abdominal Aortic Aneurysm. Academic pathology Petriceks, A. H., Olivas, J. C., Salmi, D. 2018; 5: 2374289518798560

  Abstract

  The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology. For additional information, and a full list of learning objectives for all three competencies, see http://journals.sagepub.com/doi/10.1177/2374289517715040.

  View details for PubMedID 30327791

• Mock gynecologic cytology proficiency testing as a milestone assessment tool for anatomic pathology residents. Journal of the American Society of Cytopathology Salmi, D. J., Toth, B. D., Kong, C. S. 2014; 4 (1): 10–15

  Abstract

  One of the major aims of the Next Accreditation System is to move toward an outcomes-based evaluation system where each accredited medical residency program must demonstrate that its residents are competent in performing the essential tasks necessary for clinical practice. Because all pathologists who sign-out or screen Papanicolaou (Pap) tests are required to pass an annual 10-slide gynecologic cytology proficiency test (PT), we developed mock PT modules as a tool for assessing competency.In 2007, we introduced mock proficiency testing with 3 distinct modules, each consisting of 3 10-slide test sets (10 ThinPrep, 10 SurePath, and 10 conventional Pap slides). Each module was administered at 3 different time points. We evaluated the following parameters: (1) performance differences between Pap preparations; (2) performance over time; (3) performance before and after initiation of one-on-one teaching sessions with cytotechnologists in 2009; and (4) quality of test slides.Residents showed improvement over time, and overall scores did not differ significantly among ThinPrep, SurePath, and conventional slide sets. The average score for the first test set was significantly higher for residents who received formal training by a cytotechnologist than for those who did not. Overall, 16 of 90 slides were misclassified by 40% or more of residents, half of which exhibited glandular abnormalities.The objective assessment provided by mock PT is a useful tool for both faculty and residents.

  View details for PubMedID 31051667

• Occult pigmented ganglioglioma in an adult male with chronic posttraumatic epilepsy. Clinical neuropathology Plowey, E. D., Vogel, H., Salmi, D., Shuer, L. M. 2013; 32 (3): 192-195

  View details for DOI 10.5414/NP300550

  View details for PubMedID 23254137

• Thrombotic Thrombocytopenic Purpura in a Child With Systemic Lupus Erythematosus JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY Thampi, S., Salmi, D., Imashuku, S., Ducore, J., Satake, N. 2011; 33 (3): 221-223

  Abstract

  We report a child with thrombotic thrombocytopenic purpura (TTP) secondary to systemic lupus erythematosus. The diagnosis was confirmed by low ADAMTS13 activity (<5%) along with the presence of a low titer inhibitor. Her clinical course was complicated by systemic lupus erythematosus, immunosuppressant therapy, and septic shock. She responded to plasma exchange and ADAMTS13 activity levels recovered. This case illustrates the heterogeneity of TTP and the difficulty of making a diagnosis of TTP. ADAMTS13 activity assay can be useful in the differential diagnosis of diseases with clinical features of thrombotic microangiopathy in pediatric patients. However, treatment needs to be decided carefully case-by-case.

  View details for DOI 10.1097/MPH.0b013e318208425d

  View details for Web of Science ID 000288694700022

  View details for PubMedID 21336165

• Neuroblastoma of Unknown Primary Site With Periorbital Bone Metastasis in a Child PEDIATRIC BLOOD & CANCER Salmi, D., Patel, C., Imashuku, S., Shimada, H., Satake, N. 2010; 55 (2): 361-363

  Abstract

  Neuroblastoma is the second most common solid tumor in children. Most tumors arise in the adrenal glands or paravertebral region. Rarely, patients present with metastatic disease but no primary site can be found despite extensive imaging. We report here a patient with a large periorbital bone metastasis and bone marrow involvement but with no known primary site.

  View details for DOI 10.1002/pbc.22524

  View details for Web of Science ID 000279559200031

  View details for PubMedID 20582979

• Diagnostic challenges in native valve fungal endocarditis producing a massive septic pulmonary embolus. Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology Salmi, D., Bhat, A., Corman, L., Raff, G., Satake, N. 2010; 51 (4): 207-210

  Abstract

  Diagnosis and treatment of Candida albicans endocarditis can be difficult. We report a case of this rare condition in which a patient on oral fluconazole presented with septic pulmonary emboli without initial echocardiographic evidence of vegetation. Rapid attainment of a tissue diagnosis, along with combined medical surgical treatment proved to be effective for this patient.

  View details for PubMedID 21060214

• Screening for and treatment of polycystic ovary syndrome in teenagers EXPERIMENTAL BIOLOGY AND MEDICINE Salmi, D. J., Zisser, H. C., Jovanovic, L. 2004; 229 (5): 369-377

  Abstract

  Polycystic ovary syndrome (PCOS) usually arises during puberty and is marked by hyperinsulinemia and hyperandrogenism. Adolescents with PCOS are at an increased risk of developing health problems later on in life such as type 2 diabetes, cardiovascular disease, and infertility. Furthermore, the physical signs of PCOS can be detrimental to a teenage girl's self-image. Early diagnosis and treatment of PCOS in adolescents are essential in ensuring adulthood health and restoring self-esteem. Treatments for an adolescent with PCOS include diet and exercise, metformin, and oral contraceptive pills. Each of these options has been shown to be effective in improving certain aspects of PCOS, and probably the best treatment plan involves some combination of them.

  View details for Web of Science ID 000222322100003

  View details for PubMedID 15096648