Valerie Chock

Associate Professor of Pediatrics (Neonatology) and, by courtesy, of Obstetrics and Gynecology (Maternal Fetal Medicine)

Clinical Focus

Neonatal-Perinatal Medicine
Neonatology

Academic Appointments

Associate Professor - University Medical Line, Pediatrics - Neonatal and Developmental Medicine
Associate Professor - University Medical Line (By courtesy), Obstetrics & Gynecology - Maternal Fetal Medicine
Member, Cardiovascular Institute
Member, Maternal & Child Health Research Institute (MCHRI)

Administrative Appointments

Associate Professor, Division of Neonatal and Developmental Medicine, Stanford University (2005 - Present)
Associate Director for Neonatal Prenatal Consultation Services, Center for Fetal and Maternal Health, LPCH (2010 - Present)
Associate Program Director for Research, Neonatology Fellowship Program, Division of Neonatal and Developmental Medicine, Stanford University (2016 - Present)

Honors & Awards

Arline and Pete Harman Endowed Faculty Scholar, Stanford Maternal and Child Health Research Institute (Sept 2020)
Pediatric Heart Center Research Award, Stanford Pediatric Research Fund-Lucile Packard Foundation for Children's Health (March 2010-March 2012)
Pilot Early Career Award, Stanford Pediatric Research Fund- Child Health Research Program (Jan 2008-2010)
NIH Mentored Career Development Award (KL2), Stanford Center for Clinical Translational Education and Research (2009-2011)

Professional Education

Medical Education: University of Hawaii at Manoa John A Burns School of Medicine (1998) HI
Residency: UCSF Pediatric Residency (2001) CA
Internship: UCSF Pediatric Residency (1999) CA
Board Certification: American Board of Pediatrics, Pediatrics (2001)
Board Certification: American Board of Pediatrics, Neonatal-Perinatal Medicine (2005)
M.S. Epi, Stanford University, Clinical Epidemiology (2011)
Fellowship, Stanford Lucile Packard Children's Hospital, Neonatology (2005)

Community and International Work

Protecting Newborn Brains: U.S.-Brazil Telemedicine Initiative, Sao Paulo, Brazil

Topic

Neonatal Neurointensive Care

Partnering Organization(s)

Populations Served

Location

Ongoing Project

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Opportunities for Student Involvement

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Contact

Academic vchock@stanford.edu

Clinical Neonatology 453 Quarry Rd MC 5660 Stanford CA 94305 Tel: (650) 723-5711 Fax: (650) 723-8351

Current Research and Scholarly Interests

Neurological monitoring in critically ill infants. Altered hemodynamics in neonates, especially in relation to prematurity, congenital heart disease, and central nervous system injury. Determination of the hemodynamic significance and effects of a patent ductus arteriosus in the preterm infant. Utilizing NIRS (near-infrared spectroscopy) and other technologies for improved monitoring in the NICU.

Clinical Trials

Brain Oxygenation-II Recruiting
More
The Brain Oxygenation-II study (BOx-II) is a phase-II, multicenter, single-arm clinical trial evaluating interventions based on near-infrared spectroscopy (NIRS) monitoring of cerebral oxygen saturation in extremely premature infants. Enrolled infants will follow a treatment guideline to maintain cerebral oxygen saturation in a target range within the first 72 hours of life. The primary outcomes will include interventions used to maintain cerebral saturation in target range, rates of cerebral hypoxia and systemic hypoxia, and a composite of death or severe brain injury detected on term-equivalent magnetic resonance imaging.
Lead Sponsor
Stanford Investigators
- Valerie Chock
View full details
Cerebral Oxygenation and Autoregulation in Preterm Infants Not Recruiting
More
Premature infants are at high risk for variations in blood pressure and oxygenation during the first few days of life. The immaturity of the premature brain may further predispose these infants to death or the development of neurologic problems. The relationship between unstable blood pressure and oxygen levels and brain injury has not been well elucidated. This study investigates the utility of near-infrared spectroscopy (NIRS), a non-invasive oxygen-measuring device, to identify preterm infants at highest risk for brain injury or death.

Stanford is currently not accepting patients for this trial. For more information, please contact Valerie Chock, MD, 650-723-5711.

Lead Sponsor
- Stanford University
Stanford Investigators
- Valerie Chock
View full details

2022-23 Courses

Independent Studies
- Directed Reading in Pediatrics
  PEDS 299 (Aut, Win, Spr)
- Early Clinical Experience
  PEDS 280 (Win, Spr)
- Graduate Research
  PEDS 399 (Aut, Win, Spr)
- Medical Scholars Research
  PEDS 370 (Aut, Win, Spr)
- Undergraduate Directed Reading/Research
  PEDS 199 (Aut, Win, Spr)

Graduate and Fellowship Programs

Neonatal-Perinatal Medicine (Fellowship Program)

All Publications

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Research Interests
Developmental Physiology and Sudden Infant Death Syndrome Research Laboratory closed in 2008.

Current effort, as Chair of Task Force and neonatal consult at the FDA, is to establish through consensus a culture of investigation and collaboration for all clinical neonatology practices: academic, corporate and community based to maximize the opportunity to participate in research effort needed for the regulatory approval of neonatal therapeutics to improve the outcome of critically ill infants.

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See Biosketch for details.

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William Benitz

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Rona Giffard

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Astrocytes, microglia and neurons interact, and have unique vulnerabilities to injury based on their patterns of gene expression and their functional roles. We focus on the cellular and molecular basis of brain cell injury in stroke. We study the effects of altering miRNA expression, altering levels of heat shock and cell death regulatory proteins. Our goal is to improve outcome by improving mitochondrial function and brain cell survival, and reducing oxidative stress and inflammation.

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Jeffrey Gould

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Alistair Philip

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Research Interests
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