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Research


Lab image
Researcher at microscope

“Our lab focus is on how vascular inflammation contributes to lung and lymphatic disease and to develop targeted therapeutics that can safely treat these conditions.” - Mark Nicolls

Research Areas

Lymphedema

Our group investigates the so-called 'third circulation', the lymphatics. 

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Lung transplantation diagram

Lung Transplantation

Loss of the functional airway microvasculature predisposes lung transplants to chronic rejection. 

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Pulmonary Hypertension

Pulmonary Hypertension is a deadly disease, currently without a cure.

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Emphysema/COPD

Emphysema/COPD

Our group recently found that loss of endothelial cell (EC) hypoxia inducible factor-2α (HIF-2α), induced by cigarette smoke, plays a key role in the development of emphysema.

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