Protein clumps affect neural stem cells
Young, resting neural stem cells have large protein clumps often associated with neurodegeneration. As stem cells age, the aggregates inhibit their ability to make new neurons, Stanford researchers say.
Antibody treatment for ‘bubble boy’ disease
In a clinical trial, participants were given an antibody to CD117, a cell surface marker, in an effort to wipe out their defective blood stem cells without high-risk chemotherapy or radiation.
IPS cells slow tumor growth in mice
Priming the immune system with induced pluripotent stem cells prevented or slowed the development of cancer in mice, Stanford researchers found.
Faculty get funding from stem cell agency
Three Stanford faculty members were awarded $6 million to support research into a blistering skin disease, transplanted stem cells and novel ways to grow blood stem cells.
Stem cells for fat have circadian clock
New discoveries about the circadian-clock machinery in the precursors to fat cells may explain why shift workers are prone to metabolic diseases, such as diabetes, a Stanford study finds.
Stem cells from sleepy mice perform worse
Although the research was done in mice, the findings have possible implications for bone marrow transplants, more properly called hematopoietic stem cell transplants, in humans.
Cells with potential to fix a broken heart
Researchers discovered, in mice, the direct progenitors to coronary artery smooth muscle cells, the important component that encases the artery and gives it strength.
Neurons can stimulate brain tumor growth
New research shows that high-grade gliomas, the deadliest human brain tumors, increase their growth by hijacking some of the machinery of neuroplasticity, which normally helps the brain form new synapses.
Early human embryos make viral proteins
Human embryos make viral proteins within days of fertilization, a new study shows. These proteins affect human gene expression and may protect the cells from infection by other viruses.
Roncarolo on advances in gene therapy
After leading successful clinical trials of gene therapy in Milan, Roncarolo hopes to build on that success at Stanford through collaboration with colleagues in the fields of genetics and stem cell science.
New way of sorting cells
The method is analogous to analyzing a smoothie to find what fruits went into making it, the researchers say.