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Sr Res Scientist-Basic Life, Ophthalmology Research/Clinical Trials
Tel: (650) 724-4699
10 Results / Page
Profiles With Related Publications
Euan A. Ashley
Associate Dean, School of Medicine, Roger and Joelle Burnell Professor of Genomics and Precision Health, Professor of Medicine (Cardiovascular Medicine), of Genetics, of Biomedical Data Science and, by courtesy, of Pathology
Cardiology, Inherited cardiovascular disease, Hypertrophic Cardiomyopathy, Cardiomyopathy, Dilated, Sports Cardiology, Heart Failure, Arrhythmogenic Right Ventricular Dysplasia, Left ventricular non-compaction cardiomyopathy, Genomic medicine, Undiagnosed disease
The Ashley lab is focused on precision medicine. We develop methods for the interpretation of whole genome sequencing data to improve the diagnosis of genetic disease and to personalize the practice of medicine. At the wet bench, we take advantage of cell systems, transgenic models and microsurgical models of disease to prove causality in biological pathways and find targets for therapeutic development.
Alfred Woodley Salter and Mabel G. Salter Endowed Professor of Pediatrics
Pediatric Cardiology, Pediatric Heart Transplantation, Pediatric Heart Failure
1. Using iPSC-derived cardiomyocytes to understand hypertrophic cardiomyopathy and heart failure associated with congenital heart disease.
2. Role of alterations in mitochondrial dycamics and function in normal physiology and disease.
3. Differences between R and L ventricular responses to stress,
4. Immune biomarkers of risk after pediatric VAD implantation.
5. Biomarkers for post-transplant lymphoproliferative disorder.
Helen M. Blau
Donald E. and Delia B. Baxter Foundation Professor, Director, Baxter Laboratory for Stem Cell Biology and Professor, by courtesy, of Psychiatry and Behavioral Sciences
Prof. Helen Blau's research area is regenerative medicine with a focus on stem cells. Her research on nuclear reprogramming and demonstrating the plasticity of cell fate using cell fusion is well known and her laboratory has also pioneered the design of biomaterials to mimic the in vivo microenvironment and direct stem cell fate. Current findings are leading to more efficient iPS generation, cell based therapies by dedifferentiation a la newts, and discovery of novel molecules and therapies.
Howard Y. Chang, MD, PhD
Virginia and D. K. Ludwig Professor of Cancer Research and Professor of Genetics
Cancer > Cutaneous (Dermatologic) Oncology, Dermatology, General Dermatology
Our research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods have provided insights into human development, cancer, and aging.
David Korn, MD, Professor of Pathology and Professor of Developmental Biology
Chromatin regulation and its roles in human cancer and the development of the nervous system. Engineering new methods for studying and controlling chromatin and epigenetic regulation in living cells.
Ph.D. Student in Stem Cell Biology and Regenerative Medicine, admitted Autumn 2021
Michael S. Kapiloff, MD, PhD
Reinhard Family Professor, Professor (Research) of Ophthalmology and, by courtesy, of Medicine (Cardiovascular Medicine)
Associate Professor (Research) of Cardiothoracic Surgery
The Karakikes Lab aims to uncover fundamental new insights into the molecular mechanisms and functional consequences of pathogenic mutations associated with familial cardiovascular diseases.
Instructor, Medicine - Cardiovascular Medicine
Heart Failure, Heart Transplantation, Mechanical Circulatory Support, Left Ventricular Assist Device, Inherited Cardiomyopathy, Hypertrophic Cardiomyopathy, Dilated Cardiomyopathy, Nonischemic cardiomyopathy, Cirrhotic Cardiomyopathy, Iron overload cardiomyopathy, Advanced Heart Failure and Transplant Cardiology
Seung K. Kim M.D., Ph.D.
KM Mulberry Professor, Professor of Developmental Biology, of Medicine (Endocrinology) and, by courtesy, of Pediatrics (Endocrinology)
We study the development of pancreatic islet cells using molecular, embryologic and genetic methods in several model systems, including mice, pigs, human pancreas, embryonic stem cells, and Drosophila. Our work suggests that critical factors required for islet development are also needed to maintain essential functions of the mature islet. These approaches have informed efforts to generate replacement islets from renewable sources for diabetes.
Gerald M. Reaven, MD, Professor of Endocrinology
Endocrinology / Diabetes, Lipid Metabolism Disorders, Endocrinology, Diabetes and Metabolism
Our research interests are in the general area of cellular lipid and lipoprotein metabolism. The work is aimed primarily at understanding the mechanisms regulating cholesterol and triglyceride accumulation in cells. We utilize a variety of techniques from cell biology, biochemistry, and molecular biology.
Douglass M. and Nola Leishman Professor of Cardiovascular Disease
Publication Topics For This Person
A Kinase Anchor Proteins
Disease Models, Animal
Embryonic Stem Cells
Gene Expression Profiling
Gene Expression Regulation
Oligonucleotide Array Sequence Analysis
Ribosomal Protein S6 Kinases, 90-kDa
Second Messenger Systems