Franco Felix

Ph.D. Student in Stem Cell Biology and Regenerative Medicine, admitted Autumn 2021

All Publications

Publications (4)

All Publications (4)
Featured Publications (1)
Journal Articles (4)

Profiles With Related Publications

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Euan A. Ashley

Associate Dean, School of Medicine, Roger and Joelle Burnell Professor of Genomics and Precision Health, Professor of Medicine (Cardiovascular Medicine), of Genetics, of Biomedical Data Science and, by courtesy, of Pathology
Clinical Focus
Cardiology, Inherited cardiovascular disease, Hypertrophic Cardiomyopathy, Cardiomyopathy, Dilated, Sports Cardiology, Heart Failure, Arrhythmogenic Right Ventricular Dysplasia, Left ventricular non-compaction cardiomyopathy, Genomic medicine, Undiagnosed disease
Research Interests
The Ashley lab is focused on precision medicine. We develop methods for the interpretation of whole genome sequencing data to improve the diagnosis of genetic disease and to personalize the practice of medicine. At the wet bench, we take advantage of cell systems, transgenic models and microsurgical models of disease to prove causality in biological pathways and find targets for therapeutic development.

533 Total Publications
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Daniel Bernstein

Alfred Woodley Salter and Mabel G. Salter Endowed Professor of Pediatrics
Clinical Focus
Pediatric Cardiology, Pediatric Heart Transplantation, Pediatric Heart Failure
Research Interests
1. Using iPSC-derived cardiomyocytes to understand hypertrophic cardiomyopathy and heart failure associated with congenital heart disease.
2. Role of alterations in mitochondrial dycamics and function in normal physiology and disease.
3. Differences between R and L ventricular responses to stress,
4. Immune biomarkers of risk after pediatric VAD implantation.
5. Biomarkers for post-transplant lymphoproliferative disorder.

347 Total Publications
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Anne Brunet

Michele and Timothy Barakett Endowed Professor
Research Interests
Our lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two short-lived model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.

142 Total Publications
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Gerald Crabtree

David Korn, MD, Professor of Pathology and Professor of Developmental Biology
Research Interests
Chromatin regulation and its roles in human cancer and the development of the nervous system. Engineering new methods for studying and controlling chromatin and epigenetic regulation in living cells.

260 Total Publications
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Aly Elezaby

Postdoctoral Medical Fellow, Cardiovascular Medicine Fellow in Medicine

12 Total Publications
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Casey Gifford

Assistant Professor of Pediatrics (Cardiology) and, by courtesy, of Genetics

25 Total Publications
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Rachel Knight Hopper

Clinical Associate Professor, Pediatrics - Cardiology
Clinical Focus
Pediatric Cardiology, Pulmonary Hypertension
Research Interests
Current research interests include:
PH related to prematurity and bronchopulmonary dysplasia
Right heart failure in children with pulmonary hypertension, imaging and biomarkers
Pulmonary hypertension related to congenital diaphragmatic hernia
Pulmonary vein stenosis in infants and children
Pulmonary hypertension in children with congenital heart disease
Clinical trials in children with PH

45 Total Publications
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Michael S. Kapiloff, MD, PhD

Reinhard Family Professor, Professor (Research) of Ophthalmology and, by courtesy, of Medicine (Cardiovascular Medicine)

21 Total Publications
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Ioannis Karakikes

Assistant Professor (Research) of Cardiothoracic Surgery
Research Interests
The Karakikes Lab aims to uncover fundamental new insights into the molecular mechanisms and functional consequences of pathogenic mutations associated with familial cardiovascular diseases.

73 Total Publications
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Masataka Kawana

Instructor, Medicine - Cardiovascular Medicine
Clinical Focus
Cardiovascular Disease, Heart Failure, Heart Transplantation, Mechanical Circulatory Support, Left Ventricular Assist Device, Inherited Cardiomyopathy, Hypertrophic Cardiomyopathy, Dilated Cardiomyopathy, Nonischemic cardiomyopathy, Cirrhotic Cardiomyopathy, Iron overload cardiomyopathy

26 Total Publications
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Caleb Lareau

Instructor, Pathology

77 Total Publications
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Jin Billy Li

Associate Professor of Genetics
Research Interests
The Li Lab is primarily interested in RNA editing mediated by ADAR enzymes. We co-discovered that the major function of RNA editing is to label endogenous dsRNAs as "self" to avoid being recognized as "non-self" by MDA5, a host innate immune dsRNA sensor, leading us to pursue therapeutic applications in cancer, autoimmune diseases, and viral infection. The other major direction of the lab is to develop technologies to harness endogenous ADAR enzymes for site-specific transcriptome engineering.

82 Total Publications