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My research interests encompass several areas of stereotactic and functional neurosurgery, including frameless stereotactic approaches for therapy delivery to deep brain nuclei; cortical physiology and its relationship to normal and pathological movement; brain-computer interfaces; and the development of novel neuromodulatory techniques for the treatment of movement disorders, epilepsy, pain, and other neurological diseases.
Deep Brain Stimulation for the Treatment of Traumatic Brain Injury
This study involves the treatment of cognitive impairment secondary to moderate to severe
brain injury using central thalamic deep brain stimulation. Although all patients will
receive stimulation continuously through a surgically implanted pacemaker-like device, half
of the patients will have the device deactivated during a blinded assessment phase. The
device will be reactivated following this assessment and patients will have the option to
continue stimulation in an open-label continuation.
Stanford is currently not accepting patients for this trial.
For more information, please contact Jaimie M Henderson, MD, 650-723-5574.
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Coordinated Reset Spinal Cord Stimulation
The goal of this study is to evaluate whether a new spinal cord stimulation paradigm, called
Coordinate Reset (CR) Stimulation, can provide equivalent or better pain relief with reduced
energy requirements. The investigators will test this new stimulation paradigm in patients
who are already undergoing spinal cord stimulation surgery. The investigators will also study
whether there are changes in electroencephalography (brain waves) associated with this new
The investigators hope to learn whether CR stimulation can provide equivalent or better pain
relief with reduced energy requirements. They also hope to learn whether there are changes in
brain function with effective CR stimulation compared to conventional stimulation.
This study will be testing a specific stimulation paradigm in people who have already
consented to have spinal cord stimulation performed for treatment of their chronic pain.
BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia
The purpose of this study is to obtain preliminary device safety information and demonstrate
proof of principle (feasibility) of the ability of people with tetraplegia to control a
computer cursor and other assistive devices with their thoughts.