Latest information on COVID-19

The Südhof Laboratory

The Laboratory of Dr. Thomas Südhof

Investigating the formation of synapses and synaptic communication

For a person to think, act, or feel, the neurons in a person’s brain must communicate continuously, rapidly, and repeatedly. This communication occurs at synapses, specialized junctions that allow neurons to exchange information on a millisecond timescale and that organize neurons in vast overlapping circuits.

When stimulated, a presynaptic neuron releases a chemical neurotransmitter signal that diffuses across the synaptic cleft to react with postsynaptic receptor neurons or muscle cells.

Thomas Südhof’s laboratory studies how synapses form in the brain, how their properties are specified, and how they accomplish the rapid and precise signaling that forms the basis for all information processing by the brain.


  • Stanford Scientist Wins Nobel Prize

    Neuroscientist Thomas Südhof, MD, professor of molecular and cellular physiology at the Stanford University School of Medicine, won the 2013 Nobel Prize in Physiology or Medicine.

About our work

Learn about the the projects we are pursuing in our lab.

Meet our team

Here you can find a list of all current and past members of our lab.

News & Notable

See the latest information and articles that we have put out.

The Supple Fund for Autism Research

Please consider making a gift to support research into Autism

Our laboratory's work is helping to conquer the “defeatism” surrounding the neurocognitive disorder known as Autism. We strive to understand the genetic and molecular mechanisms at play behind this disorder so that we may further understand how best to adress Autism spectrum disorders. Your support will go directly to fund innovative, nobel-prize winning science. By making a donation, you are not only helping to advance the scientific understanding of disease, but also giving families, like the Supples, the gift of hope.