School of Medicine
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Lisa Zaba, MD, PhD
Clinical Associate Professor, Dermatology
Bio Lisa Zaba M.D. Ph.D., is Clinical Associate Professor of Dermatology and Director of the South Bay Cutaneous Oncology Program. She has a special interest in managing skin complications in cancer patients while they receive treatment including skin rashes, graft versus host disease, and skin cancer. She also has a special interest in rheumatologic diseases and autoimmunity that can be caused by some forms of immune based chemotherapeutics. At the South Bay Cancer Center (CCSB) she leads the multi-disciplinary melanoma clinic. Dr. Zaba completed medical school at Cornell University, PhD in immunology at Rockefeller University, Residency and Post-Doc at Stanford University in 2013.
Clinical Associate Professor, Psychiatry and Behavioral Sciences - Child and Adolescent Psychiatry
Current Research and Scholarly Interests Dr. Zack is involved with ongoing research related to the treatment of adolescent and adult trauma (Trauma Focused Cognitive Behavioral Therapy - TF-CBT; Prolonged Exposure - PE), and the effective provision of Dialectical Behavior Therapy (DBT) to adolescent girls and women with disorder of emotion regulation. She additionally studies Acceptance and Commitment Therapy (ACT) for adolescent girls with anxiety. More broadly she is interested in the impact of Evidenced Based Treatments on improving quality of life, and helping individuals find the right match for clinical care. Research is conducted through the Early Life Stress and Pediatric Anxiety Disorders Program at Stanford Children's Hospital and the Stanford Dialectical Behavior Therapy Program.
Ken Zafren, MD FAAEM FACEP FAWM
Clinical Professor, Emergency Medicine
Current Research and Scholarly Interests High altitude medicine, AMS, HACE, HAPE, cold injuries, including hypothermia and frostbite, emergency medical services, wilderness medicine, mountain rescue, thrombosis, international medicine, travel medicine, emergency medicine, resuscitation
Professor of Radiology (Neuroimaging and Neurointervention)
Current Research and Scholarly Interests Improving medical image quality using deep learning artificial intelligence
Imaging of cerebral hemodynamics with MRI and CT
Noninvasive oxygenation measurement with MRI
Clinical imaging of cerebrovascular disease
Imaging of cervical artery dissection
MR/PET in Neuroradiology
Resting-state fMRI for perfusion imaging and stroke
Yulia Zak, MD
Clinical Assistant Professor, Surgery - General Surgery
Bio Dr. Yulia Zak earned her medical degree from SUNY Downstate Medical Center before completing general surgery residency at Stanford University and advanced minimally invasive gastrointestinal and bariatric fellowship training at the Massachusetts General Hospital. Dr. Zak is certified by the American Board of Surgery and American Society for Metabolic and Bariatric Surgery. She has also completed the Stanford Surgical Education and Simulation fellowship and was previously an Assistant Program Director for the general surgery residency program at Mount Sinai Beth Israel. Dr. Zak joined the faculty at Stanford in 2018 and is the current Fellowship Associate Program Director. Her current clinical practice is focused on bariatrics, foregut and abdominal wall procedures. Her academic interests include quality improvement, surgical education, and bariatric outcomes.
Clinical Assistant Professor, Radiation Oncology - Radiation Therapy
Bio Dr. Zaky is a board certified Radiation Oncologist. She received a Bachelor’s of Science in Biomedical/Electrical Engineering at Marquette University. She worked in research and development as an Engineer, and eventually received a Masters of Science in Immunology from Albany Medical College. Her research thesis focused on a novel therapy to treat hormone-receptor positive breast cancer. She continued to study breast cancer with her research during her Radiation Oncology residency; she integrated her research in the laboratory with her clinical research in triple-negative breast cancer. Since completing residency, she has worked as a general radiation oncologist, and her special interests include breast cancer, skin cancer, CNS tumors and stereotactic radiotherapy.
Associate Professor of Medicine (Pulmonary and Critical Care Medicine) at the Stanford University Medical Center
Current Research and Scholarly Interests 1. Development and evaluation of prognostic and diagnostic integral biomarkers in PAH.
2. Prevalence and Treatment of Insulin Resistance in PAH.
3. Role of inflammation and proteomic signature in PAH
4. Development of novel therapeutics (bench to bedside) including FK506 & Elastase Inhibition in PAH.
5. Assessment of Vasoreactivity (gain and loss) in pulmonary arterial hypertension
6. Assessment of microvascular function in PAH.
Marguerite Blake Wilbur Professor in Natural Science and Professor, by courtesy, of Physics
Current Research and Scholarly Interests My research group is exploring a variety of topics that range from the basic understanding of chemical reaction dynamics to the nature of the chemical contents of single cells.
Under thermal conditions nature seems to hide the details of how elementary reactions occur through a series of averages over reagent velocity, internal energy, impact parameter, and orientation. To discover the effects of these variables on reactivity, it is necessary to carry out studies of chemical reactions far from equilibrium in which the states of the reactants are more sharply restricted and can be varied in a controlled manner. My research group is attempting to meet this tough experimental challenge through a number of laser techniques that prepare reactants in specific quantum states and probe the quantum state distributions of the resulting products. It is our belief that such state-to-state information gives the deepest insight into the forces that operate in the breaking of old bonds and the making of new ones.
Space does not permit a full description of these projects, and I earnestly invite correspondence. The following examples are representative:
The simplest of all neutral bimolecular reactions is the exchange reaction H H2 -> H2 H. We are studying this system and various isotopic cousins using a tunable UV laser pulse to photodissociate HBr (DBr) and hence create fast H (D) atoms of known translational energy in the presence of H2 and/or D2 and using a laser multiphoton ionization time-of-flight mass spectrometer to detect the nascent molecular products in a quantum-state-specific manner by means of an imaging technique. It is expected that these product state distributions will provide a key test of the adequacy of various advanced theoretical schemes for modeling this reaction.
Analytical efforts involve the use of capillary zone electrophoresis, two-step laser desorption laser multiphoton ionization mass spectrometry, cavity ring-down spectroscopy, and Hadamard transform time-of-flight mass spectrometry. We believe these methods can revolutionize trace analysis, particularly of biomolecules in cells.
Christopher K. Zarins
Walter Clifford Chidester and Elsa Rooney Chidester Professor of Surgery, Emeritus
Current Research and Scholarly Interests Hemodynamic factors in atherosclerosis, pathogenesis of, aortic aneurysms, carotid plaque localization and complication, anastomotic intimal hyperplasia, vascular biology of artery wall, computational fluid dynamics as applied to blood flow and vascular disease.
James L. Zehnder, M.D.
Professor of Pathology (Research) and of Medicine (Hematology) at the Stanford University Medical Center
Current Research and Scholarly Interests Our laboratory focuses on translational research in 2 main areas - genomic approaches to diagnosis and minimal residual disease testing for patients with cancer, and molecular basis of disorders of thrombosis and hemostasis. My clinical focus is in molecular pathology, diagnosis and treatment of disorders of hemostasis and thrombosis and general hematology.
Assistant Professor of Radiology (Neuroimaging and Neurointervention) at the Stanford University Medical Center
Bio Dr. Michael Zeineh received a B.S. in Biology at Caltech in 1995 and obtained his M.D.-Ph.D. from UCLA in 2003. After internship also at UCLA, he went on to radiology residency and neuroradiology fellowship both at Stanford. He has been an assistant professor of radiology since 2010. Combining clinical acumen in neuroradiology with advanced MRI acquisition and image processing as well as histologic validation, Dr. Zeineh hopes to advance the care of patients with neurodegenerative disorders. In particular, he is interested in Alzheimer's disease, sports-related mild traumatic brain injury, and chronic fatigue syndrome. Additionally, he is specifically interested and has over 20 years of experience studying hippocampal anatomy and pathology.
Associate Professor (Research) of Psychiatry and Behavioral Sciences (Sleep Medicine)
Current Research and Scholarly Interests Dr. Zeitzer is a circadian physiologist specializing in the understanding of the impact of light on circadian rhythms and other aspects of non-image forming light perception.
He examines the manner in which humans respond to light and ways to manipulate this responsiveness, with direct application to jet lag, shift work, and altered sleep timing in teens. Dr. Zeitzer has also pioneered the use of actigraphy in the determination of epiphenomenal markers of psychiatric disorders.
Bing Melody Zhang
Clinical Assistant Professor, Pathology
Current Research and Scholarly Interests My research interests lie in two main areas:
1) Using genetic/genomic approaches to study the genotype-phenotype correlation of inherited non-malignant hematologic disorders, especially platelet disorders.
2) Development and validation of molecular assays for clinical testing to support organ transplantation.
Clinical Assistant Professor, Neurology & Neurological Sciences
Bio Dr. Niushen Zhang specializes in the treatment of headache and facial pain. Dr. Zhang has a special interest in complementary and alternative medicine for the treatment of headaches and facial pain. She is the Director of the Headache Fellowship Program at Stanford.
Professor (Research) of Neurosurgery
Current Research and Scholarly Interests My lab is focused on developing novel therapeutic methods against stroke using rodent models. We study protective effect of postconditioning, preconditioning and mild hypothermia. The rationale for studying three means of neuroprotection is that we may discover mechanisms that these treatments have in common. Conversely, if they have differing mechanisms, we will be able to offer more than one treatment for stroke and increase a patients chance for recovery.
Instructor, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly Interests Novel and integrative interventions for pain management
Professor of Medicine (Infectious Diseases) at the Stanford University Medical Center, Emeritus
Current Research and Scholarly Interests Dr. Zolopas research applies a variety of clinical epidemiologic methods in an effort to optimize antiretroviral therapy and understand the impact of drug resistance on response to ARV. Areas of focus include the clinical application of resistance testing in optimizing antiretroviral therapy, clinical cohorts, trials of antiretroviral therapies and population-based epidemiologic evaluation of HIV resistance and efficacy of ARV therapy. More recently studies focused on premature aging in HIV.
J. Bradley Zuchero
Assistant Professor of Neurosurgery
Current Research and Scholarly Interests Glia are a frontier of neuroscience, and overwhelming evidence from the last decade shows that they are essential regulators of all aspects of the nervous system. The Zuchero Lab aims to uncover how glial cells regulate neural development and how their dysfunction contributes to diseases like multiple sclerosis (MS) and in injuries like stroke.
Although glia represent more than half of the cells in the human brain, fundamental questions remain to be answered. How do glia develop their highly specialized morphologies and interact with neurons to powerfully control form and function of the nervous system? How is this disrupted in neurodegenerative diseases and after injury? By bringing cutting-edge cell biology techniques to the study of glia, we aim to uncover how glia help sculpt and regulate the nervous system and test their potential as novel, untapped therapeutic targets for disease and injury.
We are particularly interested in myelin, the insulating sheath around neuronal axons that is lost in diseases like MS. How do oligodendrocytes- the glial cell that produces myelin in the central nervous system- form and remodel myelin, and why do they fail to regenerate myelin in disease? Our current projects aim to use cell biology and neuroscience approaches to answer these fundamental questions. Ultimately we hope our work will lead to much-needed therapies to promote remyelination in patients.
Clinical Assistant Professor, Radiology - Pediatric Radiology
Bio Dr. Zucker is a board-certified pediatric and cardiovascular radiologist with a special interest in CT and MRI for congenital heart disease.
Assistant Professor of Medicine (General Medical Disciplines)
Current Research and Scholarly Interests - Improving care and supporting self-management for patients with multiple chronic conditions
- Designing and evaluating innovative health care delivery models for complex and costly patients
- Optimizing health-related technology to personalize and improve care for complex patients and their caregivers
Assistant Professor of Neurosurgery at the Stanford University Medical Center
Current Research and Scholarly Interests My goal is to translate research into real-world action and decision-making so that my work can impact patients and the institutions in which they receive care. With a research focus on healthcare cost and quality of care, I approach neurosurgery in a unique way—one that applies business operations, economics, and healthcare delivery principles to our field. I have pursued formal LEAN business training, and believe in the importance of working together with other departments and administrators, as well as physicians and surgeons on the hospital and national level, to effect change. During my residency, I developed and led a multi-departmental prospective study at UCSF called OR SCORE (OR Surgical Cost Reduction Project) that brought together surgeons from the neurosurgery, orthopedics and ENT departments with nurses and administrators. OR SCORE successfully reduced surgical supply costs by nearly one million dollars in its first year by providing >60 surgeons with price transparency scorecards. This work led to a first-author publication in JAMA Surgery, but more importantly, set the foundation for further quality improvement and cost reduction efforts across the UCSF hospital system.
A volunteer neurosurgical mission trip to Guadalajara, Mexico, where limited resources create an OR environment that is strikingly more frugal than the U.S., inspired me to lead another project aimed at quantifying and reducing operating room waste at UCSF. I have also conducted research looking at the safety and outcomes of overlapping surgery, as well as several projects to define the factors underlying variation in cost for neurosurgical care using UCSF’s hospital data and national databases like the National Inpatient Sample, Vizient (formerly known as University Health Consortium), and Medicare.
As a clinical fellow at Johns Hopkins, I continued and expanded these research efforts. I designed and implemented an Enhanced Recovery after Surgery (ERAS) protocol at the Johns Hopkins Bayview hospital. This protocol standardized care for our spine patients, emphasizing pre-operative rehabilitation, psychiatric and nutritional assessments, and smoking cessation, as well as intra- and post-operative multi-modal pain therapy, early mobilization, and standardized antibiotic and bowel regimens. I also collaborated with engineers in the Johns Hopkins Carnegie Center for Surgical Innovation to develop better algorithms for intra-operative CT imaging, and provided assistance with operations to a basic science study looking at the role of cerebrospinal fluid drainage and duraplasty in a porcine model of spinal cord injury.
At Stanford, I am building a research group focused on: (1) perfecting paradigms for delivery of high-end technology in spinal care, including robotics and navigation, (2) implementing cost and quality strategies in large healthcare systems, and (3) computational analysis of big-data to effect real-time risk stratification and decision making in spine surgery. I'm excited to collaborate with my peers across surgical and medical departments, as well as business and engineering colleagues.