Susan Knox Publications
2014
Hiniker SM, Knox SJ. Immunotherapy and Radiation. Seminars in Oncology. Semin Oncol. 2014 Dec;41(6):702-713. PMID: 25499631
Bazan J, Chang P, Balog R, D'Andrea A, Shaler T, Lin H, Lee S, Harrison T, Shura L, Schoen L, Knox SJ, Cooper DE. Novel human radiation exposure biomarker panel applicable for population triage. International Journal of Radiation Oncology Biology Physics. 2014 Nov 1;90(3):612-619. PMID: 25084613
Oronsky B, Oronsky N, Knox S, Fanger G, Scicinski J. Episensitization: Therapeutic Tumor Resensitization by Epigenetic Agents: A Review and Reassessment. Anti-Cancer Agents in Medicinal Chemistry. 2014;14(8):1121-1127. PMID: 24893730 PMCID: PMC4262965
Oronsky B, Fanger G, Oronsky N, Knox SJ, Scicinski J. The implications of hyponitroxia in cancer. Transl Oncol April 2014, 7(2):167-173. PMID: 24731473
Ning S, Bednarski M, Oronsky B, Scicinski J, Knox SJ. Novel nitric oxide generating compound glycidyl nitrate enhances the therapeutic efficacy of chemotherapy and radiotherapy. Biochem Biophys Res Commun. 2014 Apr 13. pii: S0006-291X(14)00663-9. PMID: 24735538
Reid T, Dad S, Korn R, Oronsky G, Knox SJ, Scicinski J. Two Case Reports of Resensitization to Previous Chemotherapy with the Novel Hypoxia-Activated Hypomethylating Anticancer Agent RRx-001 in Metastatic Colorectal Cancer Patients. Case Rep Oncol. 2014 Jan 24;7:79-85; PMID: 24575021
2013
Leung, TH, Zhang, LF, Wang J, Ning S, Knox SJ, Kim SK. Topical hypochlorite ameliorates NF-kB-mediated skin diseases in mice. J Clin Invest. 2013 Dec 2;123(12):5361-70. PMID: 24231355 PMCID: PMC3859383
Tian J, Doi H, Zhao H, Nolley R, Reese SW, Young SR, Li X, Peehl DM, Knox SJ. Radioproduction and cell cycle arrest of intestional epithelial cells by darinaparsin, a tumor radiosensitizer. Int J Radiat Oncol Biol Phys. 2013 Dec 1;87(5):1179-85. PMID: 24210080
Paulmurugan R, Oronsky B, Brouse CF, Reid T, Knox SJ, Maltrey R, Scicinski J. Real time dynamic imaging and current targeted therapies in the war in cancer: a new paradigm. Theranostics. 2013 May 25;3(6):437-47. PMID: 23781290 PMCID: PMC3677414
Vaklavas C, Meredith RF, Shen S, Knox SJ, Micallef IN, Shah JJ, Lobuglio AF, Forero-Torres A. Phase I Study of a Modified Regimen of (90)Yttrium-Ibritumomab Tiuxetan for Relapsed or Refractory Follicular or Transformed CD20+ Non-Hodgkin Lymphoma. Cancer Biother Radiopharm. 2013 Jun;28(5):370-9. PMID: 23530878
Parker J, Jones JC, Strober S, Knox SJ. Characterization of direct radiation-induced immune function and signaling changes in antigen presenting cell line. Clin Immunol. 2013; 148 (1): 44-55. PMID 23649044
2012
Hiniker SM, Chen DS, Reddy S, Chang DT, Jones JC, Mollick JA, Swetter SM, Knox SJ. A systemic complete response of metastatic melanoma to local radiation and immunotherapy. Transl Oncol 2012 Dec:5(6):404-407. PMID: 23323154
Ning S, Budas GR, Churchill EN, Chen CH, Knox SJ, Mochly-Rosen D. Mitigation of radiation-induced dermatitis by activation of aldehyde dehydrogenase 2 using topical alda-l in mice. Radiat Res. 2012 Jul;178(1):69-74. PMID: 22404739
Oronsky BT, Knox SJ, Scicinski JJ. Is Nitric Oxide (NO) the Last Word in Radiosensitization? A Review. Transl Oncol. 2012 Apr;5(2):66-71. Epub 2012 Apr 1. PMID: 22496921
Tian J, Zhao H, Nolley R, Reese SW, Young SR, Li X, Peehl DM, Knox SJ. Darinaparsin: solid tumor hypoxic cytotoxin and radiosensitizer. Clin Cancer Res. 2012 Jun 15;18(12):3366-76. Epub 2012 Apr 25. PMID: 22535156
Ning S, Bednarski M, Oronsky B, Scicinski J, Saul G, Knox SJ. Dinitroazetidines are a novel class of anticancer agents and hypoxia-activated radiation sensitizers developed from highly energetic materials. Cancer Res. 2012 May 15;72(10):2600-8. PMID: 22589277
Hiniker SM, Chen DS, Knox SJ, Abscopal effect in a patient with melanoma. N Engl J Med. 2012 May 24;366(21):2035; author reply 2035-2036. PMID: 22621637
Oronsky BT, Scicinski JJ, Reid T, Knox SJ. Beyond antiangiogenesis: vascular modulation as an anticancer therapy-a review. Transl Oncol. 2012 Jun;5(3):133-140. Epub 2012 Jun 1. PMID: 22741032
Oronsky BT, Reid T, Knox SJ, Scicinski JJ. The scarlet letter of alkylation: a mini review of selective alkylating agents. Transl Oncol. 2012 Aug;5(4):226-229. Epub 2012 Aug 1. PMID: 22937173
2011
Oronsky B, Knox SJ, Scicinski J. Six degrees of separation: The oxygen effect in the development of radiosensitizers. Translational Oncology 2011, 4(4):189-198. PMID: 21804913
2010
Tian J, Ning S, Knox SJ. Sodium selenite radiosensitizes hormone-refractory prostate cancer xenograft tumors but not intestinal crypt cells in vivo. Int J Radiat Oncol Biol Phys. 2010; 78 (1): 230-236. PMID: 20615620
Tian J, Peehl DM, Knox SJ. Metalloporphyrin synergizes with ascorbic acid to inhibit cancer cell growth through fenton chemistry. Cancer Biother Radiopharm. 2010; 25 (4): 439-448. PMID: 20735206
Brody JD, Ai WZ, Czerwinski DK, Torchia JA, Levy M, Advani RH, Kim YH, Hoppe RT, Knox, SJ, Shin LK, Wapnir I, Tibshirani RJ, Levy R. In Situ Vaccination With a TLR9 Agonist Induces Systemic Lymphoma Regression: A Phase I/II Study. J Clin Oncol. 2010, Oct1,28(28):4324-4332. PMID: 20697067
Ning S, Tian J, Marshall DJ, Knox SJ. Anti-{alpha}v Integrin Monoclonal Antibody Intetumumab Enhances the Efficacy of Radiation Therapy and Reduces Metastasis of Human Cancer Xenografts in Nude Rats. Cancer Res. 2010, Oct 1;70(19):7591-7599. PMID: 20841470
Tian J, Peehl DM, Zheng W, Knox SJ. Anti-tumor and radiosensitization activities of the iron chelator HDp44mT are mediated by effects on intracellular redox status. Cancer Lett. 2010, Dec 8;298(2):231-237. PMID: 20678860
Iagaru A, Mittra ES, Ganjoo K, Knox SJ, Goris ML. 131I-Tositumomab (Bexxar(R)) vs. 90Y-Ibritumomab (Zevalin(R)) Therapy of Low-Grade Refractory/Relapsed Non-Hodgkin Lymphoma. Mol Imaging Biol 2010, 12(2):198-203. PMID 19543946
2009
Shen S, Forero A, Meredith RF, Shah J, Knox SJ, Wiseman GA, LoBuglio AF Impact of Rituximab Treatment on 90Y-Ibritumomab Dosimetry or Patients with Non-Hodgkin's Lymphnoma. J Nucl Med 2009, 51(1):150-157. PMID 20008989
Ning S, Knox SJ, Harsh GR, Culler M, Katznelson L. Lanreotide promotes apoptosis and is not radioprotective in GH3 cells. In Press in Endocr Relat Cancer. Endocrine-Related Cancer 2009, Sep;16(3):1045-1055. PMID 19528243