Clinical Trials Directory

Accelerated Partial Breast Irradiation Following Lumpectomy for Breast Cancer

To determine whether an accelerated course of radiotherapy delivered to the lumpectomy cavity plus margin using IORT as a single dose, intracavitary brachytherapy with the MammoSite device over 5 days, partial breast 3-D CRT in 5 days, or stereotactic APBI over 4 days is a feasible and safe alternative to a six and a half week course of whole breast radiotherapy. The study will measure both short and long-term complications of radiation treatment, short and long-term breast cosmesis, local rates of in-breast cancer recurrence, regional recurrences, distant metastases, and overall survival.

Stanford is not currently accepting new patients for this trial. You may want to check to see if other locations are recruiting.



  • procedure : Lumpectomy
  • radiation : Stereotactic APBI
  • radiation : Intracavitary Brachytherapy
  • radiation : Accelerated External Beam 3-D Conformal Radiotherapy
  • radiation : Intra-Operative Radiotherapy (IORT)
  • radiation : Whole Breast Radiotherapy

Phase: N/A


Ages Eligible For Study:

40 Years - N/A

Inclusion Criteria

1. Women >= 40 with invasive ductal carcinoma or ductal carcinoma in situ 2. Patient chooses lumpectomy rather than mastectomy as treatment for breast cancer 3. Tumor < 2.5 cm in size, 2 mm margin of normal breast tissue between cancer and edge of specimen.

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Contact information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Sally Bobo
Not Recruiting

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