October 1, 2014 | Stanley Qi joined Stanford Bioengineering & Chemical and Systems Biology

We have moved to the new home for bioengineering and chemical engineering, the Shriram Center. Our lab is housed on the third floor of the building, with our microscope room in the basement. The building offers cutting-edge facilities on imaging, biochemistry, biophysics, and animal facilities.

As a joint department in both the School of Engineering and the School of Medicine, the Department of Bioengineering focus on combining the tools of engineering with a deep understanding of complex living systems. 

Besides Bioengineering, Dr. Qi is also affiliated with the Department of Chemical and Systems Biology and ChEM-H.

Jan 28, 2015 | CRISPR Synthetic Circuits

Our recent work on using CRISPR as transcriptional regulatory tools for constructing complex genetic circuits in mammalian cells was published in Cell this week. In this story jointly work Dr. Wendell Lim at UCSF and Dr. John Dueber at UC Berkeley, we've devised CRISPR as useful parts to re-direct metabolic pathways, control cell mobility, and multplexed control of endogenous networks in mammalian systems. 

The paper is reported by Stanford News, "Stanford bioengineers develop tool for reprogramming genetic code"; and io9, "New Technique Allows Bioengineers To "Reprogram" Genetic Code".

We are excited about the possibility of using dCas9-based technologies for gene regulation to scale up our capabilities of engineering complex artificial genetic systems with applications in cell therapeutics, stem cell engineering, and large-scale genome-wide screening.

Feb 5, 2015 | Drugs for enhancing genome editing

Our recent work showed that small molecule can be used to enhance or reduce the efficacy of using CRISPR for genome editing. We have performed chemical screening and identifies several drugs as potent enhancers or mitigators of CRISPR genome editing. These small molecules first proved that small molecules are effective regulators of genome engineering, and also provides new ways to modulate in vivo applications of gene therapy and cell therapy based on genome engineering. 

The leading-authors of the papers are Chen Yu and Yanxia Liu. 

The authors have filed a related patent to the use of small molecules for genome editing. 

Aug 1, 2015 | Stanley taught at the Cold Spring Harbor Lab Synthetic Biology Course

Stanley taught as one of the instructors at the Cold Spring Harbor Laboratory Course on Synthetic Biology. Eddy also taught as the teaching assistant. 

Nov 11, 2015 | New lab in the Bioengineering Building Shriram Center

We have moved into the new custom-designed lab space located on the third floor Room 376 in the Shriram Center. 

Jan 4, 2016 | dCas9 for non-editing genome engineering

The Atlantic highlighted our work on using nuclease-free CRISPR/dCas9 technologies for non-editing based genome manipulation and disease research. The full article is available here. 

April 7, 2016 | Antonia Dominguez spotlighted by ALS Association

The ALS Association published an interview with Antonia Dominguez for her research and career. The full article is available here.

July 10, 2016 | The Qi Lab is awarded Blue Flame Award from Addgene for contribution to sharing engineered DNA materials. 

November 6, 2016 | Stanley Qi gives a speech at the Tencent WE 2016

As the only invited speaker to talk about healthcare, Stanley highlighted the potentials and risks associated with the revolutionary CRISPR genome engineering technology. 

To view the full video, click here. 

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