Small Animal Imaging Facility Stanford Center for Innovation in In-Vivo Imaging (SCI3)

The mission of the Stanford Center for Innovation in In-Vivo Imaging (SCI3) is the application and advancement of technologies for in-vivo biological assessment and imaging in animal models. The instrumentation will support the development of reagents and approaches that will reveal in-vivo changes at the molecular and cellular level such that a greater understanding can be gained in animal models.

In this manner the power of repeated measures can be applied to these models enriching the data sets and improving the statistics. This core will provide a test bed for evaluating human imaging reagents and strategies.

The flexibility and rapid analyses of the animal models will greatly accelerate the development of these molecular imaging strategies as well as novel therapeutic strategies for a variety of diseases. The Clark Building houses the SCI3 core resources and instrumentation.

The Small Animal Imaging Core Facility is partially supported by funds from the Stanford Digestive Disease Core, the Stanford Comprehensive Cancer Center, and is operated by the Departments of Pediatrics (Neonatology) and Radiology.

SCI3 Directors

Christopher Contag, PhD

Dr. Contag is a Professor, Departments of Pediatrics and of Microbiology and Immunology and, by courtesy, of Radiology, and directs the SCI3.

Sanjiv Sam Gambhir, MD, PhD

Dr. Gambhir is the Virginia & D.K. Ludwig Professor of Cancer Research Professor, Chair of the Department of Radiology, Professor by courtesy of Bioengineering and and Material Science Engineering, and co-directs the SCI3.

Craig Levin, PhD

Dr. Levin is a Professor of Radiology, and, by courtesy, of Physics, of Electrical Engineering and of Bioengineering, and co-directs the SCI3.

Michael Moseley, PhD

Dr. Moseley is a Professor of Radiology and is the Director of Experimental MRI and MRS at the Lucas MR Center. He directs the MR imaging and spectroscopy aspects of the SCI3.

Tim Doyle, PhD

Dr. Doyle is Scientific Director of the Small Animal Imaging Facility, and oversees its day-to-day running, providing training and assistance with the instruments.

SCI3 Research Staff

Tim Doyle, Ph.D.

Dr. Doyle provides training on the IVIS Imaging Systems (both bioluminescence and fluorescence imaging), MicroCT scannersMicroSPECT scanners, and the Vevo Ultrasound, and provides regular training sessions on these systems. He can also show users how to use the Leica (Mauna Kea) Cellvizio microscopecryomicrotome and cryomacrotome systems.

Laura Jean Pisani, PhD

Dr Pisani manages the 7T MRI system, providing training and assistance for all users on this system - please coordinate directly with her to arrange for this. She also provides training on the use of radionuclides in the imaging facility, as well as training on the MicroPET systems. Finally, Dr Pisani provides training on the ART Optix and CRI Maestro fluorescence imaging systems.

Frezghi Habte, PhD

Dr Habte provides image quantification assistance to all users of the imaging facility. He runs regular software training classes focusing on different software applications used within the facility, as well as providing assistance with specific problems as required.

SCI3 Quicklinks

Instrument Training