ME/CFS in the Department of Medicine
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Stanford Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Initiative

An initiative dedicated to studying infection-associated chronic diseases

Mission Statement

To become a center of excellence that improves the health of patients with chronic diseases in which infection or its immune response plays a major etiologic role.

To provide leadership, facilitate multidisciplinary collaboration, make new discoveries, and educate in the field of infection-associated chronic diseases.


Our primary aim is to study the roles that infection and the immune response play in the symptoms of patients suffering from chronic, unexplained diseases.

Recent News

Dr. Montoya and his research was recently featured in an ABC7 News feature about ME/CFS. Check out the video on the ABC7 website.

"An imaging study by Stanford University School of Medicine investigators has found distinct differences between the brains of patients with chronic fatigue syndrome and those of healthy people."

Immune System Disruption: The search for answers

Dear Patients, Researchers and Supporters of the ME/CFS Stanford Research, 

The video capture from the 2014 Stanford Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Symposium hosted on March 19, 2014 is now available to the public. Please follow this link to access the video from this event. If you find these materials helpful and would like to make a contribution to our research, please click on the link below.    

Make a Gift

Your donation will help us continue unraveling the mystery of this debilitating illness.

Kindest regards,

The Stanford ME/CFS Initiative

Dear Stanford ME/CFS Clinic patients,

Dr. Montoya's Stanford University ME/CFS Initiative is helping to support  the International Association for Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis (IACFS/ME) 11th Biennial Conference this year. The meeting will take place March 20-23, 2014 at the Parc 55 Hotel in San Francisco and will feature physicians and researchers from around the US and the world.  Dr. Montoya will be welcoming patient attendees as well as speaking on antivirals during part of the conference. If you would like to attend, please visit for more details and/or see the attached announcement. If you have any questions, please e-mail  You can register up to and even on the first day of the Conference but register before January 31 for the lowest fee. I hope to see you there!

Lily Chu, MD, MS
Board member, IACFS/ME
Advisory board member, Stanford ME/CFS Initiative

The Stanford ME/CFS Initiative is pleased to host the 2014 Stanford Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome Symposium: Advances in Clinical Care and Translational Research for health care providers. We invite all interested health care providers and allied health to attend. This CME eligible conference will take place on March 19, 2014 at the Li Ka Shing Center for Learning and Knowledge, Stanford, California. The goal is to bring awareness about ME/CFS to the Medical Community. For questions on the event, please contact Yolanda Cervantes.

ENROLLMENT COMPLETED for Synergy Trial. Thank you very much for your interest and/or participation. The Synergy Trial: A Clinical Trial investigating a Combination of a CFS Nutrient Formula plus a Currently Available Medication to treat Chronic Fatigue Syndrome

Randomized clinical trial to evaluate the efficacy and safety of valganciclovir in a subset of patients with chronic fatigue syndrome. (please note this link will direct you to a webpage unaffiliated with Stanford University)

Persistent human herpesvirus-6 infection in patients with an inherited form of the virus. (please note this link will direct you to a webpage unaffiliated with Stanford University)

Daily cytokine fluctuations, driven by leptin, are associated with fatigue severity in chronic fatigue syndrome: evidence of inflammatory pathology.(please note this link will direct you to a webpage unaffiliated with Stanford University)

Please see our 2013 Newsletter of all the progress from our ME/CFS research team!

We would like to introduce two new physician assistants, Jane Norris and Aimee Jadav, respectively, to our clincal care team. Please learn more about Jane and Aimee here!

Stanford has a ME/CFS Biobank of stored research samples

Response to valganciclovir in Chronic Fatigue Syndrome patients with human herpesvirus 6 and Epstein-Barr viru IgG antibdy titers. (please note this link will direct you to a webpage unaffiliated with Stanford University)

We have recently added a new physician assistant, Amity Hall, to our ME/CFS clinical care team. Please learn more about Amity Hall here!

A multicenter blinded analysis indicates no association between chronic fatigue syndrome/myalgic encephalomyelitis and either xenotropic murine leukemia virus-related virus of polytropic murine leukemia virus. (please note this link will direct you to a webpage unaffiliated with Stanford University)

We have recently launched a new web page specifically designed for ME/CFS patients. On this page you will find information on how to navigate our website, tips on managing your health, and clinical updates.

Dr. A. Martin Lerner has released a diagnostic and treatment resource guide for ME/CFS. In addition to this resource guide, Dr. Lerner has a video presentation available online which details his diagnostic and treatment protocol. (Please see August 20, 2011, Part 1 and Part 2 for this information)

Benefit from B-Lymphocyte Depletion Using the Anti-CD20 Antibody Rituximab in Chronic Fatigue Syndrome. A Double-Blind and Placebo-Controlled Study. (please note this link will direct you to a webpage unaffiliated with Stanford University)

Current Areas of Study
Infection-associated chronic diseases that our group studies include Chronic Fatigue Syndrome, Chronic Lyme Disease, Epilepsy, Multiple Sclerosis, and other unexplained chronic illnesses. We are interested in learning more about how infectious agents may play an etiologic role in these diseases. These infectious agents include human herpesvirus-6 (HHV-6), retroviruses such as xenotropic murine leukemia virus-related virus (XMRV), parasites such as Toxoplasma gondii, fungi such as Coccidiodes immitis, and bacteria such as Borrelia burgdorferi (the cause of Lyme disease).

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