Current Research and Scholarly Interests
Currently working on unraveling the mechanisms of Alzheimer's disease progression and resilience utilizing mass cytometry (CyTOF) and high-dimensional imaging (multiplexed ion beam imaging - MIBI).
Previously worked on evaluating the role of immune cells in allergic pathogenesis (IgE+ B cells, regulatory B cells or Bregs, basophils, type 2 innate lymphoid cells, eosinophils).
Collaborated on research projects with a few research groups, which include:
- The Hospital for Sick Children, Division of Pediatric Emergency Medicine and Pediatric Research Academic Initiative in SickKids Emergency (PRAISE) Program
- McMaster Children's Hospital, Division of Urology and the Clinical Urology Research Enterprise (CURE) Program
- St. Joseph's Healthcare Center Hamilton, Division of Otolaryngology and Head and Neck Surgery
Research interests include:
- The immunobiology and pathophysiology of allergic diseases (allergic asthma, allergic rhinitis)
- The role and function of regulatory B cells in disease (autoimmunity, inflammation, cancer)
- The role of immune cells (B cells, T cells, eosinophils, basophils) in the pathogenesis of disease
- Single cell analyses and 'omics' technologies including: RNAseq, CyTOF, flow and imaging cytometry
- Translational immunology, clinical drug development and clinical trials, "big data", and machine learning
- Effectiveness of active learning in undergraduate and graduate level education